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The map label for this gene is cph1 [H]

Identifier: 39997539

GI number: 39997539

Start: 2678697

End: 2680529

Strand: Reverse

Name: cph1 [H]

Synonym: GSU2444

Alternate gene names: 39997539

Gene position: 2680529-2678697 (Counterclockwise)

Preceding gene: 39997540

Following gene: 39997538

Centisome position: 70.28

GC content: 63.88

Gene sequence:

>1833_bases
ATGGCCGGACGCGGATATGCCAGTCGCCTGTCGATTCTGTCCGCGTCCGCGCTGATTCTGGCGCTCGTTGTCATCCTCGC
AGCCACCGGAGGCTCCCGCGCCGAATCCGGCGCCGTGTCCCTGACCCCCGAGGAGCGGGCGTGGCTCAACGCCCATCCGG
TCATCAAGCTCGCCCCGGACCCCGACTTCAAACCCATCGAGTATTTTGACGAAAACGGCGTCTACCGCGGGGCAGCGGCC
GACCACATCCACGCCCTGGAAAAAAAGCTCGGCATCACCATCACCATCGTTCACCTGCGGAACTGGGACGAGGTCATGGA
TGCCTTCAAACGGCACGAGGTGGACCTGCTCGGGGCGGTGGCCGCCACACCGGACCGGGAACGGTACATGCTGTTCAGCG
ATCCCCTGGTGGTGGTCCCCGGCGGGATCTTCTCGGCCAGGGAGTTCGGCAAGCCCCTTGCCATCAAGGATCTGCAGGGG
CTGAAGGTGGCCGTGGTTTCCAACTACATGGCCCACGACTACCTGCGTAACACCTATCCGCAGATAAGCCTGGATATCGT
GCCGGACGTCTCCACGGGGCTGGCCAAGGCATCCCTGGGGATGGTGGACGTCTACGTGGAAAACATGGCCAACGCCACCT
TTTATCTCCAGGAGGCTGGGATCACCAACCTCCGGCTCGTGGGGAACACCGATTTCATGTACCGCTGGGGGATCGGCATC
CGCAAGGACTGGCCCATGATGCGGCAGATCCTCAATAAGGGGCTCGCGGCATTGAGCGAGGATGAAAAGAGTGCCCTCAT
CGGGCGCTGGATTTATGTGAAGGCCCCGCCCTGGCGGCCGAGCAGGGCATTTGTGGCGGGAATGGTTGCTTCGGTTGCGG
GCGTGCTGCTGGTGGCGGCGGTGTCGATCAACCTGACGCTCAAGAGGAAAGTGAACGCGCGGACCGCGGAACTGCAGGGT
GAACTGGCTGAGCGCCGAAGGCTGGAACAAGAGCTTACCCGCCTGAACGAGCAGCTGGAGGAGCGGGTCCGGGAGCGGAC
TGCCGAGCTGGAGCGCCAGGTGGCCGACCGCCGGCGGGCCGAGGAGGCGCTCCAGCAACTCACCGTCGGGCTGGAACAAC
GGGTGAAGGCCCGTACCGCCGAACTGGAGGCCTCCAACCGGGAGCTGGAATCGTTCACCTTCGCGGTGTCCCATGATCTG
CGGGCGCCGGTGAGGCACATCAACGGCTATGTCGAGATACTCACCGAGGAACTGGCGGCCAAGGAGTGCCTCTGCGCGGG
CGATTATCTCGCCCGGATCATGGTCTCCTGCCGGCGGATGCAGGAGATGATCGACTCGCTCCTGGACCTTTCCCGGATAA
GCCGCAAAGAGCTCCAGTGCGAACAGGTCGACCTGAGCGAAATCGCCCGGCAGATCATGGCTGAAATGCGAGAGGCCGAG
CCCCATCGCCGCGTGGAAGCGACCATCGCCGACGGGATCAGGGCCAAGGGAGACCCGGTCCTGCTCCGCAGCGTCATCGA
AAACCTGCTGCACAATGCCTGGAAATACACCGGCAGGAAAGACGTGGCCCACATCGAGTTCGGCGTCGACACCGGGGGCG
GGGAAACCGTCTACTACGTCCGCGACGACGGGGCCGGCTTTGATGCCGCATACGCAGGCAAACTGTTCACCCCCTTCCAG
AGACTCCACACCGATGCCGAGTTCACCGGCACCGGAGTCGGCCTTGCCACGGTGCAGCGGATTATCCACCGGCACCGCGG
CAGGGTCTGGGCCTTCTCCGAGCCCGGCCGGGGGGCATGTTTCTTCTTTACCCTGAATACCGAAACCGCATGA

Upstream 100 bases:

>100_bases
GCGGGAAGGAAATCGTCACCCTGCTGGACGTCTCGGACCGGCAGCGGCAGGAACTGCTGGCCGGCGGGACGTTGAACTAC
GTGAAACGGAGCGCCTGACC

Downstream 100 bases:

>100_bases
GGTGACCCATGGCAACCACGCTCCGCGCCATCCTTCCCGATTCCGAGCTGCTGAAGATGCACGAACAGATGGTCCTCTCC
CGCGAGTTCGAGGAATCGTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MAGRGYASRLSILSASALILALVVILAATGGSRAESGAVSLTPEERAWLNAHPVIKLAPDPDFKPIEYFDENGVYRGAAA
DHIHALEKKLGITITIVHLRNWDEVMDAFKRHEVDLLGAVAATPDRERYMLFSDPLVVVPGGIFSAREFGKPLAIKDLQG
LKVAVVSNYMAHDYLRNTYPQISLDIVPDVSTGLAKASLGMVDVYVENMANATFYLQEAGITNLRLVGNTDFMYRWGIGI
RKDWPMMRQILNKGLAALSEDEKSALIGRWIYVKAPPWRPSRAFVAGMVASVAGVLLVAAVSINLTLKRKVNARTAELQG
ELAERRRLEQELTRLNEQLEERVRERTAELERQVADRRRAEEALQQLTVGLEQRVKARTAELEASNRELESFTFAVSHDL
RAPVRHINGYVEILTEELAAKECLCAGDYLARIMVSCRRMQEMIDSLLDLSRISRKELQCEQVDLSEIARQIMAEMREAE
PHRRVEATIADGIRAKGDPVLLRSVIENLLHNAWKYTGRKDVAHIEFGVDTGGGETVYYVRDDGAGFDAAYAGKLFTPFQ
RLHTDAEFTGTGVGLATVQRIIHRHRGRVWAFSEPGRGACFFFTLNTETA

Sequences:

>Translated_610_residues
MAGRGYASRLSILSASALILALVVILAATGGSRAESGAVSLTPEERAWLNAHPVIKLAPDPDFKPIEYFDENGVYRGAAA
DHIHALEKKLGITITIVHLRNWDEVMDAFKRHEVDLLGAVAATPDRERYMLFSDPLVVVPGGIFSAREFGKPLAIKDLQG
LKVAVVSNYMAHDYLRNTYPQISLDIVPDVSTGLAKASLGMVDVYVENMANATFYLQEAGITNLRLVGNTDFMYRWGIGI
RKDWPMMRQILNKGLAALSEDEKSALIGRWIYVKAPPWRPSRAFVAGMVASVAGVLLVAAVSINLTLKRKVNARTAELQG
ELAERRRLEQELTRLNEQLEERVRERTAELERQVADRRRAEEALQQLTVGLEQRVKARTAELEASNRELESFTFAVSHDL
RAPVRHINGYVEILTEELAAKECLCAGDYLARIMVSCRRMQEMIDSLLDLSRISRKELQCEQVDLSEIARQIMAEMREAE
PHRRVEATIADGIRAKGDPVLLRSVIENLLHNAWKYTGRKDVAHIEFGVDTGGGETVYYVRDDGAGFDAAYAGKLFTPFQ
RLHTDAEFTGTGVGLATVQRIIHRHRGRVWAFSEPGRGACFFFTLNTETA
>Mature_609_residues
AGRGYASRLSILSASALILALVVILAATGGSRAESGAVSLTPEERAWLNAHPVIKLAPDPDFKPIEYFDENGVYRGAAAD
HIHALEKKLGITITIVHLRNWDEVMDAFKRHEVDLLGAVAATPDRERYMLFSDPLVVVPGGIFSAREFGKPLAIKDLQGL
KVAVVSNYMAHDYLRNTYPQISLDIVPDVSTGLAKASLGMVDVYVENMANATFYLQEAGITNLRLVGNTDFMYRWGIGIR
KDWPMMRQILNKGLAALSEDEKSALIGRWIYVKAPPWRPSRAFVAGMVASVAGVLLVAAVSINLTLKRKVNARTAELQGE
LAERRRLEQELTRLNEQLEERVRERTAELERQVADRRRAEEALQQLTVGLEQRVKARTAELEASNRELESFTFAVSHDLR
APVRHINGYVEILTEELAAKECLCAGDYLARIMVSCRRMQEMIDSLLDLSRISRKELQCEQVDLSEIARQIMAEMREAEP
HRRVEATIADGIRAKGDPVLLRSVIENLLHNAWKYTGRKDVAHIEFGVDTGGGETVYYVRDDGAGFDAAYAGKLFTPFQR
LHTDAEFTGTGVGLATVQRIIHRHRGRVWAFSEPGRGACFFFTLNTETA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=30.5019305019305, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=283, Percent_Identity=30.3886925795053, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=31.9327731092437, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788549, Length=214, Percent_Identity=28.9719626168224, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789149, Length=290, Percent_Identity=24.4827586206897, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=26.271186440678, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=27.3913043478261, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789808, Length=239, Percent_Identity=26.7782426778243, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=22.9838709677419, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790346, Length=207, Percent_Identity=29.951690821256, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=214, Percent_Identity=28.5046728971963, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790551, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=26.6968325791855, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790861, Length=223, Percent_Identity=26.0089686098655, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68015; Mature: 67884

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRGYASRLSILSASALILALVVILAATGGSRAESGAVSLTPEERAWLNAHPVIKLAPD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCC
PDFKPIEYFDENGVYRGAAADHIHALEKKLGITITIVHLRNWDEVMDAFKRHEVDLLGAV
CCCCCCCEECCCCEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCHHHHHHH
AATPDRERYMLFSDPLVVVPGGIFSAREFGKPLAIKDLQGLKVAVVSNYMAHDYLRNTYP
HCCCCCCCEEEEECCEEEECCCCHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHHHCCCC
QISLDIVPDVSTGLAKASLGMVDVYVENMANATFYLQEAGITNLRLVGNTDFMYRWGIGI
CEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCEEEEECCCC
RKDWPMMRQILNKGLAALSEDEKSALIGRWIYVKAPPWRPSRAFVAGMVASVAGVLLVAA
CCCCHHHHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VSINLTLKRKVNARTAELQGELAERRRLEQELTRLNEQLEERVRERTAELERQVADRRRA
HHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEALQQLTVGLEQRVKARTAELEASNRELESFTFAVSHDLRAPVRHINGYVEILTEELAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KECLCAGDYLARIMVSCRRMQEMIDSLLDLSRISRKELQCEQVDLSEIARQIMAEMREAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCC
PHRRVEATIADGIRAKGDPVLLRSVIENLLHNAWKYTGRKDVAHIEFGVDTGGGETVYYV
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEE
RDDGAGFDAAYAGKLFTPFQRLHTDAEFTGTGVGLATVQRIIHRHRGRVWAFSEPGRGAC
ECCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEE
FFFTLNTETA
EEEEECCCCC
>Mature Secondary Structure 
AGRGYASRLSILSASALILALVVILAATGGSRAESGAVSLTPEERAWLNAHPVIKLAPD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCC
PDFKPIEYFDENGVYRGAAADHIHALEKKLGITITIVHLRNWDEVMDAFKRHEVDLLGAV
CCCCCCCEECCCCEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCHHHHHHH
AATPDRERYMLFSDPLVVVPGGIFSAREFGKPLAIKDLQGLKVAVVSNYMAHDYLRNTYP
HCCCCCCCEEEEECCEEEECCCCHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHHHCCCC
QISLDIVPDVSTGLAKASLGMVDVYVENMANATFYLQEAGITNLRLVGNTDFMYRWGIGI
CEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCEEEEECCCC
RKDWPMMRQILNKGLAALSEDEKSALIGRWIYVKAPPWRPSRAFVAGMVASVAGVLLVAA
CCCCHHHHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VSINLTLKRKVNARTAELQGELAERRRLEQELTRLNEQLEERVRERTAELERQVADRRRA
HHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEALQQLTVGLEQRVKARTAELEASNRELESFTFAVSHDLRAPVRHINGYVEILTEELAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KECLCAGDYLARIMVSCRRMQEMIDSLLDLSRISRKELQCEQVDLSEIARQIMAEMREAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCC
PHRRVEATIADGIRAKGDPVLLRSVIENLLHNAWKYTGRKDVAHIEFGVDTGGGETVYYV
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEE
RDDGAGFDAAYAGKLFTPFQRLHTDAEFTGTGVGLATVQRIIHRHRGRVWAFSEPGRGAC
ECCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEE
FFFTLNTETA
EEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]