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The map label for this gene is dfrA [H]

Identifier: 39997333

GI number: 39997333

Start: 2450222

End: 2450602

Strand: Reverse

Name: dfrA [H]

Synonym: GSU2235

Alternate gene names: 39997333

Gene position: 2450602-2450222 (Counterclockwise)

Preceding gene: 39997334

Following gene: 39997331

Centisome position: 64.25

GC content: 61.68

Gene sequence:

>381_bases
ATGAAAGAGATTGTTGCGACAGAACAGGCACCCAAGGCGATCGGTCCCTATTCCCAGGCGGTGAGGGCAGGGGGATTCCT
GTTCCTGTCGGGTCAGATACCCCTTGATCCCGCCACCGGCGAAATGGTCGACGGGGACATCACGGTTCAGACGATGCGCG
TAATGGACAACATGGCCGCAGTACTGGCCGAGGCGGGGCTCGGATTTGACGCCATCGTGAAGACGACGATCTTTCTTGCG
GATCTCGCCGATTTTGCCGCCGTGAACGGGGTCTACGGCAGCCGCTTTGCTGCGGCGCCGCCGGCTCGTTCCACCGTGGA
GGTGAAAGGGCTTCCCCGGGGAGCTCTCGTGGAGATCGAGGCGATCGCGCTCTGTCAGTAA

Upstream 100 bases:

>100_bases
GACGTCACCGACCTGGATCACCTGAAGCGGGTAATGAACAACATCATGAAGCTGAGCGGTGTCATTTCGGTCGAGCGAAT
GAAAAATTGAAGGGGGGAGC

Downstream 100 bases:

>100_bases
GGGGCGGATGGTGGTTGTCTGCGGGGTCTGCCGGTGTTGGAACGACAAAAAGCCGCACGCGCTTACGCGCTGCGGCTCAG
TCATTTCGTGCCGTGGTGAA

Product: endoribonuclease L-PSP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MKEIVATEQAPKAIGPYSQAVRAGGFLFLSGQIPLDPATGEMVDGDITVQTMRVMDNMAAVLAEAGLGFDAIVKTTIFLA
DLADFAAVNGVYGSRFAAAPPARSTVEVKGLPRGALVEIEAIALCQ

Sequences:

>Translated_126_residues
MKEIVATEQAPKAIGPYSQAVRAGGFLFLSGQIPLDPATGEMVDGDITVQTMRVMDNMAAVLAEAGLGFDAIVKTTIFLA
DLADFAAVNGVYGSRFAAAPPARSTVEVKGLPRGALVEIEAIALCQ
>Mature_126_residues
MKEIVATEQAPKAIGPYSQAVRAGGFLFLSGQIPLDPATGEMVDGDITVQTMRVMDNMAAVLAEAGLGFDAIVKTTIFLA
DLADFAAVNGVYGSRFAAAPPARSTVEVKGLPRGALVEIEAIALCQ

Specific function: Unknown

COG id: COG0251

COG function: function code J; Putative translation initiation inhibitor, yjgF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RutC family [H]

Homologues:

Organism=Homo sapiens, GI5032215, Length=124, Percent_Identity=41.9354838709677, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI87082396, Length=127, Percent_Identity=49.6062992125984, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI87082213, Length=127, Percent_Identity=45.6692913385827, Blast_Score=107, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71982075, Length=124, Percent_Identity=49.1935483870968, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25148896, Length=124, Percent_Identity=49.1935483870968, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71982068, Length=124, Percent_Identity=49.1935483870968, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322138, Length=120, Percent_Identity=42.5, Blast_Score=100, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320899, Length=103, Percent_Identity=41.747572815534, Blast_Score=84, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19921376, Length=124, Percent_Identity=44.3548387096774, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013813
- InterPro:   IPR006175
- InterPro:   IPR006056
- InterPro:   IPR019897 [H]

Pfam domain/function: PF01042 Ribonuc_L-PSP [H]

EC number: NA

Molecular weight: Translated: 13069; Mature: 13069

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS01094 UPF0076

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIVATEQAPKAIGPYSQAVRAGGFLFLSGQIPLDPATGEMVDGDITVQTMRVMDNMAA
CCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHH
VLAEAGLGFDAIVKTTIFLADLADFAAVNGVYGSRFAAAPPARSTVEVKGLPRGALVEIE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEE
AIALCQ
EEEECC
>Mature Secondary Structure
MKEIVATEQAPKAIGPYSQAVRAGGFLFLSGQIPLDPATGEMVDGDITVQTMRVMDNMAA
CCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHH
VLAEAGLGFDAIVKTTIFLADLADFAAVNGVYGSRFAAAPPARSTVEVKGLPRGALVEIE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEE
AIALCQ
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA