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The map label for this gene is baeS [H]

Identifier: 39997242

GI number: 39997242

Start: 2361163

End: 2362452

Strand: Reverse

Name: baeS [H]

Synonym: GSU2144

Alternate gene names: 39997242

Gene position: 2362452-2361163 (Counterclockwise)

Preceding gene: 39997243

Following gene: 39997241

Centisome position: 61.94

GC content: 57.91

Gene sequence:

>1290_bases
GTGCGCGATTTCACTCTTCTTGCCGAAGCAGAGCAGGAGGACCGCGTCTCATGGGTCGTCACCGACCTGGAATCCGCCTT
TGCCAACCAGAAAGGGTGGGACAAGGCGATGGCGGCGGAAGACTCCATCTGGGCGCTTCAACTCGGCCTGGAAACCCGTC
TGGTGGACCTGGACGGCAAAACCGTCATGGAAACTGCCGTAGCGCTGAACTCTTTGCAGCCGGAACAGCGGGCACGTTTC
AAACATGGAACTCGCACCGACTCCGCGCCCGGCAAGGGTGACTACCACGCCTATCCTCTGTTTCACCACGGCGAGGAAGT
CGGACAACTGGAAGTCAGGTTTCTTCCAGATGAGCGCAACCGTGTCTTCATTGCGCGAACCAACCGGCTCCTCACCTATT
CGGCCATCATTCTCGGTATTGCGGCCTGCATCCTGAGCGTCATCTTTGCCCGCCGGTTGAGCCGTCCGATCATCAGGATA
TCGCAGGCAGCGCACGACATCAGCCAGGGTAATCTGACCGAACGCGTCGCTATATCCGGCAACGATGAGCTGGCTGCCCT
TGGCCAGTCGTTCAACCAGATGGCGCACACTCTCCAGGTACAGAACAAACTGCGCAAGCAGATCTGCGCCAACCTTGCCC
ATGAATTGCGTACCCCGCTGACCGTCATGCGAGGGCAGCTTGAAGGTATTCTGGACGGTGTATTGCCGAATGACACGTCA
CGCATGAGCCTGCTCCTTGAAGAGAACCAGCGGCTCACTAAGATTGTGGCTTCGATGGAGGAGTTTTTTCAGGCCCAGGC
CAGCGCCCTCAGTCTTGCCCCCGTCAATCTGAACGTCAGGCAGATATTCGATAATCTGGCAACATACTTCGAGGCTGCCG
CCCGTAACCTTGAGATAGAGTTCAGGGTAGAGACTGACGATGGTGCCACGGTCTATGCCGACCCCGAACGGCTCTCGCAG
ATTCTCATCAATCTGATCAGTAATAGTCTCAAGGCAACGGCTCCGGGAGGCGCCATAACGCTTGGTGCCAGGAGGACCCC
GGATGGTTGCTCCCTCACAGTAGCCGACACCGGTTGCGGCATCGCCGCAGAAGAACTCCCCCTGATATTCGAGCGGTTCT
ACCGGGGTAAAGACGGCGGGCTCGGGCTCGGACTCGCCATCGTCAGGGAACTGGCAGATGCGCACGGCGCATCCATCAGC
GTCACCAGTAACCAGGCGGTAGGAACAACAATTTCACTGGCGTTTCCCGACAAGGCGGAATCTCCACAATTCTCCACAAC
CGCTTCATAA

Upstream 100 bases:

>100_bases
CGCTTCGGTGGCGTACCGGATGTTTAAGAAATTCCTGATCATACTGCTGTTCATGGCCGGCCTGGGGGTGACTTCGGCGG
TTCTGCTCCGGGAATTGGTC

Downstream 100 bases:

>100_bases
TTGTCCCACACTCCTTTGTTACGATGAAACCATCGATAGCAATACTTCATCACAAAGGAGAATTATCATGAACAAGGGGA
TTATTGCAGTAGTAGCAGTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRDFTLLAEAEQEDRVSWVVTDLESAFANQKGWDKAMAAEDSIWALQLGLETRLVDLDGKTVMETAVALNSLQPEQRARF
KHGTRTDSAPGKGDYHAYPLFHHGEEVGQLEVRFLPDERNRVFIARTNRLLTYSAIILGIAACILSVIFARRLSRPIIRI
SQAAHDISQGNLTERVAISGNDELAALGQSFNQMAHTLQVQNKLRKQICANLAHELRTPLTVMRGQLEGILDGVLPNDTS
RMSLLLEENQRLTKIVASMEEFFQAQASALSLAPVNLNVRQIFDNLATYFEAAARNLEIEFRVETDDGATVYADPERLSQ
ILINLISNSLKATAPGGAITLGARRTPDGCSLTVADTGCGIAAEELPLIFERFYRGKDGGLGLGLAIVRELADAHGASIS
VTSNQAVGTTISLAFPDKAESPQFSTTAS

Sequences:

>Translated_429_residues
MRDFTLLAEAEQEDRVSWVVTDLESAFANQKGWDKAMAAEDSIWALQLGLETRLVDLDGKTVMETAVALNSLQPEQRARF
KHGTRTDSAPGKGDYHAYPLFHHGEEVGQLEVRFLPDERNRVFIARTNRLLTYSAIILGIAACILSVIFARRLSRPIIRI
SQAAHDISQGNLTERVAISGNDELAALGQSFNQMAHTLQVQNKLRKQICANLAHELRTPLTVMRGQLEGILDGVLPNDTS
RMSLLLEENQRLTKIVASMEEFFQAQASALSLAPVNLNVRQIFDNLATYFEAAARNLEIEFRVETDDGATVYADPERLSQ
ILINLISNSLKATAPGGAITLGARRTPDGCSLTVADTGCGIAAEELPLIFERFYRGKDGGLGLGLAIVRELADAHGASIS
VTSNQAVGTTISLAFPDKAESPQFSTTAS
>Mature_429_residues
MRDFTLLAEAEQEDRVSWVVTDLESAFANQKGWDKAMAAEDSIWALQLGLETRLVDLDGKTVMETAVALNSLQPEQRARF
KHGTRTDSAPGKGDYHAYPLFHHGEEVGQLEVRFLPDERNRVFIARTNRLLTYSAIILGIAACILSVIFARRLSRPIIRI
SQAAHDISQGNLTERVAISGNDELAALGQSFNQMAHTLQVQNKLRKQICANLAHELRTPLTVMRGQLEGILDGVLPNDTS
RMSLLLEENQRLTKIVASMEEFFQAQASALSLAPVNLNVRQIFDNLATYFEAAARNLEIEFRVETDDGATVYADPERLSQ
ILINLISNSLKATAPGGAITLGARRTPDGCSLTVADTGCGIAAEELPLIFERFYRGKDGGLGLGLAIVRELADAHGASIS
VTSNQAVGTTISLAFPDKAESPQFSTTAS

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=274, Percent_Identity=33.9416058394161, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790436, Length=371, Percent_Identity=25.3369272237197, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=30.8880308880309, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786783, Length=301, Percent_Identity=31.5614617940199, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=30.2040816326531, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=28.3088235294118, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790861, Length=329, Percent_Identity=29.483282674772, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082128, Length=279, Percent_Identity=27.2401433691756, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787894, Length=323, Percent_Identity=28.1733746130031, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789149, Length=345, Percent_Identity=25.7971014492754, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=27.7272727272727, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788279, Length=290, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87081816, Length=335, Percent_Identity=24.7761194029851, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=27.5555555555556, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789808, Length=306, Percent_Identity=25.1633986928105, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=25.6809338521401, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=30.0813008130081, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790551, Length=329, Percent_Identity=25.2279635258359, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790300, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46820; Mature: 46820

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFTLLAEAEQEDRVSWVVTDLESAFANQKGWDKAMAAEDSIWALQLGLETRLVDLDGK
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCEEEEEECCCH
TVMETAVALNSLQPEQRARFKHGTRTDSAPGKGDYHAYPLFHHGEEVGQLEVRFLPDERN
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEECCCHHCCCCCCCEEEEECCCCCC
RVFIARTNRLLTYSAIILGIAACILSVIFARRLSRPIIRISQAAHDISQGNLTERVAISG
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECC
NDELAALGQSFNQMAHTLQVQNKLRKQICANLAHELRTPLTVMRGQLEGILDGVLPNDTS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCH
RMSLLLEENQRLTKIVASMEEFFQAQASALSLAPVNLNVRQIFDNLATYFEAAARNLEIE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
FRVETDDGATVYADPERLSQILINLISNSLKATAPGGAITLGARRTPDGCSLTVADTGCG
EEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCC
IAAEELPLIFERFYRGKDGGLGLGLAIVRELADAHGASISVTSNQAVGTTISLAFPDKAE
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCC
SPQFSTTAS
CCCCCCCCC
>Mature Secondary Structure
MRDFTLLAEAEQEDRVSWVVTDLESAFANQKGWDKAMAAEDSIWALQLGLETRLVDLDGK
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCEEEEEECCCH
TVMETAVALNSLQPEQRARFKHGTRTDSAPGKGDYHAYPLFHHGEEVGQLEVRFLPDERN
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEECCCHHCCCCCCCEEEEECCCCCC
RVFIARTNRLLTYSAIILGIAACILSVIFARRLSRPIIRISQAAHDISQGNLTERVAISG
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECC
NDELAALGQSFNQMAHTLQVQNKLRKQICANLAHELRTPLTVMRGQLEGILDGVLPNDTS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCH
RMSLLLEENQRLTKIVASMEEFFQAQASALSLAPVNLNVRQIFDNLATYFEAAARNLEIE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
FRVETDDGATVYADPERLSQILINLISNSLKATAPGGAITLGARRTPDGCSLTVADTGCG
EEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCC
IAAEELPLIFERFYRGKDGGLGLGLAIVRELADAHGASISVTSNQAVGTTISLAFPDKAE
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCC
SPQFSTTAS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]