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The map label for this gene is baeR [H]

Identifier: 39997243

GI number: 39997243

Start: 2362526

End: 2363224

Strand: Reverse

Name: baeR [H]

Synonym: GSU2145

Alternate gene names: 39997243

Gene position: 2363224-2362526 (Counterclockwise)

Preceding gene: 39997244

Following gene: 39997242

Centisome position: 61.96

GC content: 55.65

Gene sequence:

>699_bases
ATGAATAATTACATTCTCCTTGTGGAGGACGATGCCGGAATTGCAGAAGTTGCTCTGGCCTATCTTGAGAACGCCGGGCT
CAAGGTCGTGCACGTGACAACAGGCAGGGATGCGCTGGATAACTCCAGAGCGGAATCTCCACTTTTGGTCGTTCTCGATC
TCATGCTCCCGGACCTCAGTGGCGAAGCAGTGTGCCGCGAACTGAAGGAGACTGCCGATATTCCGGTGGTCATCATCACC
GCCAAGGCTTCAGAGGAGGAACGTCTGGCCGGGTTCGCCCTGGGAGCCGATGACTATGTCGTCAAGCCGTTTAGTCCACG
TGAACTTGTGGCACGCGTACAGGCGGTGCTGAAGCGGGCGGGAAAGAATGCGGATGGAGGAAAGCGGCTCAGTTTCAACA
GGGGAGAATTGGTTGTCGATGACCGCAACTATACCGTGACCTGCCGGGGGACTTCCGTAAAATTGACGGCAGTGGAATTC
AAGGTGCTCCACACCCTCGCGGCCAGACCGCAGAAAACCTTTACCCGTGAGGAACTGGTAGACAGGGCGATGGGGTATCA
GTTCGAAGGCTATGAACGGAATATCGATTCCCACATCAAGAACATCCGGCATAAGCTGAGTGACAGCCCGAAGGCGCCGA
CATATGTCATAACGGTGTACGGCCTGGGCTACCGCTTCGGTGGCGTACCGGATGTTTAA

Upstream 100 bases:

>100_bases
ATTGTGCTTGATATCATCAATCTCGCGAAGTGAGAAGAAAGCTGTCATTGGCAAGGCCCGATTCCCCTCTGTCGGAGCTC
ATGCACAAGGGATGATCGAC

Downstream 100 bases:

>100_bases
GAAATTCCTGATCATACTGCTGTTCATGGCCGGCCTGGGGGTGACTTCGGCGGTTCTGCTCCGGGAATTGGTCGTGCGCG
ATTTCACTCTTCTTGCCGAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNNYILLVEDDAGIAEVALAYLENAGLKVVHVTTGRDALDNSRAESPLLVVLDLMLPDLSGEAVCRELKETADIPVVIIT
AKASEEERLAGFALGADDYVVKPFSPRELVARVQAVLKRAGKNADGGKRLSFNRGELVVDDRNYTVTCRGTSVKLTAVEF
KVLHTLAARPQKTFTREELVDRAMGYQFEGYERNIDSHIKNIRHKLSDSPKAPTYVITVYGLGYRFGGVPDV

Sequences:

>Translated_232_residues
MNNYILLVEDDAGIAEVALAYLENAGLKVVHVTTGRDALDNSRAESPLLVVLDLMLPDLSGEAVCRELKETADIPVVIIT
AKASEEERLAGFALGADDYVVKPFSPRELVARVQAVLKRAGKNADGGKRLSFNRGELVVDDRNYTVTCRGTSVKLTAVEF
KVLHTLAARPQKTFTREELVDRAMGYQFEGYERNIDSHIKNIRHKLSDSPKAPTYVITVYGLGYRFGGVPDV
>Mature_232_residues
MNNYILLVEDDAGIAEVALAYLENAGLKVVHVTTGRDALDNSRAESPLLVVLDLMLPDLSGEAVCRELKETADIPVVIIT
AKASEEERLAGFALGADDYVVKPFSPRELVARVQAVLKRAGKNADGGKRLSFNRGELVVDDRNYTVTCRGTSVKLTAVEF
KVLHTLAARPQKTFTREELVDRAMGYQFEGYERNIDSHIKNIRHKLSDSPKAPTYVITVYGLGYRFGGVPDV

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=38.0530973451327, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=36.0169491525424, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.3982300884956, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.5217391304348, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=35.2422907488987, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.8701298701299, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=31.7180616740088, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=32.3008849557522, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=29.6137339055794, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=32.0175438596491, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=29.9107142857143, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=28.0701754385965, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.0316742081448, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=27.9475982532751, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25523; Mature: 25523

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYILLVEDDAGIAEVALAYLENAGLKVVHVTTGRDALDNSRAESPLLVVLDLMLPDLS
CCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCCCCCEEEEEHHCCCCC
GEAVCRELKETADIPVVIITAKASEEERLAGFALGADDYVVKPFSPRELVARVQAVLKRA
HHHHHHHHHHHCCCCEEEEEECCCCCHHHEEEEECCCCEEECCCCHHHHHHHHHHHHHHC
GKNADGGKRLSFNRGELVVDDRNYTVTCRGTSVKLTAVEFKVLHTLAARPQKTFTREELV
CCCCCCCCEEECCCCCEEEECCCEEEEEECCEEEEEEHHHHHHHHHHCCCCHHHHHHHHH
DRAMGYQFEGYERNIDSHIKNIRHKLSDSPKAPTYVITVYGLGYRFGGVPDV
HHHHCCEECCHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEECCCCCCC
>Mature Secondary Structure
MNNYILLVEDDAGIAEVALAYLENAGLKVVHVTTGRDALDNSRAESPLLVVLDLMLPDLS
CCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCCCCCEEEEEHHCCCCC
GEAVCRELKETADIPVVIITAKASEEERLAGFALGADDYVVKPFSPRELVARVQAVLKRA
HHHHHHHHHHHCCCCEEEEEECCCCCHHHEEEEECCCCEEECCCCHHHHHHHHHHHHHHC
GKNADGGKRLSFNRGELVVDDRNYTVTCRGTSVKLTAVEFKVLHTLAARPQKTFTREELV
CCCCCCCCEEECCCCCEEEECCCEEEEEECCEEEEEEHHHHHHHHHHCCCCHHHHHHHHH
DRAMGYQFEGYERNIDSHIKNIRHKLSDSPKAPTYVITVYGLGYRFGGVPDV
HHHHCCEECCHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]