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The map label for this gene is czcC [H]

Identifier: 39997235

GI number: 39997235

Start: 2354577

End: 2355890

Strand: Reverse

Name: czcC [H]

Synonym: GSU2137

Alternate gene names: 39997235

Gene position: 2355890-2354577 (Counterclockwise)

Preceding gene: 39997236

Following gene: 39997234

Centisome position: 61.77

GC content: 57.15

Gene sequence:

>1314_bases
ATGGAGGTTATTTCATTGGGAACAACAGTATTCGCACGGGGAGCCTTGCTCCTAGTGCCAGGAATTGCCGTTTTATTGTC
GTCCACCCTGGTTCGGGCTGACGAGCCGTCCCTGTCATTGCCCAAGGTTATCGAGTACTCGCTGCAAAATAATGGCGAAC
TCAAAGCACTGCGGGAGGAAAAAGGTGTCCGCGATGCCAGCAAGTTCAGGGCCGGTCTCCTGCCCAACCCGACTCTCGAT
CTGGAAGCCGGCACCGGTGCCCTGACCGGCAGCAGCGACGAAAACAACCTGACGATTGGGGTCTCCCAGGAATTTCTGCT
GGCGGGCAAGCGTGACAAGCGCCTGACCGTTGCTGAACGCGAACTGGAAGCCTATCGCTGGCAGTTGGCTGATCGCGAAC
GAACATTACGGGAAGAAGTAAAGGCCGTATTCTATGACGTCATGCTTGCCGAACAGCGGCTCAAGCTGACGGACCGCTCC
ATTGATCTTAACCGGCAACTTCTTGAGGTCACCAAGGATCGTCTGGCCGCCGGTGACATTCCCGAACTGGAGATGAATCT
GGCCAAGGTTGAGTTGACCCGTAGCGAAGGTGCCCGGATCGAGGTCGAGCGGGCGCTTCTGCAAACAAGATCCAGACTCT
TTGCCTTCATGGGGCTGCCTGCCGGTGAAGCACCGGCGATTGCCGGGACCCTGGATAACGGCTTTTCCCTCAACAAGAAT
CTGGCTGACCTGAAGCAGCTGGCGCTTGGCCTACGCCCCGATCTGAAGGCGCTGGAGGCCGAAAAAGGGCGGGGTGACGC
GGACATCACCCTTGCCGAGGCTGAGAAAGTTCCCAACCTCACGGCAGGCCTTTTCTATACCCATGACCGCAGAACAGACG
CAACCGGCACAGGGGAAGAAAAAGTCCGCGACAACCTGCTTGGCATCCGGCTTTCAATGCCGATCCCAGTGTTCGACAAG
AATCAGGCCGGCCTTCAGGAAGCCCGGGCCAAACGGAGCAGCAGTGAAAGCCGTTTGACTGCTGCTACCAGGATCGTGGA
GCGGGACGTAGAGACCGCCTATATCAGCGCTCTGAATGCCGAGAAGGTGCTGTCGCTCTATAAGTCAAACATCATTCCCC
AACTTGAGGAAAACCTGAAACTGACCCAGGAGGCGTACCGGCTGGGTGAGGTCGGGATTCTCTCAGTCATCCAGGAACAG
AAGAAATTCTTCGAGGTCAGCGACGGCTATCTGACGGCGCTCCATGACCGGCAGCTGGCACTCGTAAAACTCGAATCAGC
AGTGGCGACAGACATCAACGGAGGTGTGCAGTGA

Upstream 100 bases:

>100_bases
TGTCGGGAGTAGTTTGTCCTGATTCCAAGGGACAACTGCATCCGCGTTGTCCGTCGTGGTACGTCCGCACCTATTATTAA
TCGTTGTAACAAAACTGAAT

Downstream 100 bases:

>100_bases
ACAAGAAAGCAATCATCATCGGACTTATCCTGGCCCTGGCCCTGGGGGGCGGCGTCGCTTACCGGCTGACCCATTCCACC
ACCGGGGGCGGAGAAAAAGC

Product: metal ion efflux outer membrane protein family protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MEVISLGTTVFARGALLLVPGIAVLLSSTLVRADEPSLSLPKVIEYSLQNNGELKALREEKGVRDASKFRAGLLPNPTLD
LEAGTGALTGSSDENNLTIGVSQEFLLAGKRDKRLTVAERELEAYRWQLADRERTLREEVKAVFYDVMLAEQRLKLTDRS
IDLNRQLLEVTKDRLAAGDIPELEMNLAKVELTRSEGARIEVERALLQTRSRLFAFMGLPAGEAPAIAGTLDNGFSLNKN
LADLKQLALGLRPDLKALEAEKGRGDADITLAEAEKVPNLTAGLFYTHDRRTDATGTGEEKVRDNLLGIRLSMPIPVFDK
NQAGLQEARAKRSSSESRLTAATRIVERDVETAYISALNAEKVLSLYKSNIIPQLEENLKLTQEAYRLGEVGILSVIQEQ
KKFFEVSDGYLTALHDRQLALVKLESAVATDINGGVQ

Sequences:

>Translated_437_residues
MEVISLGTTVFARGALLLVPGIAVLLSSTLVRADEPSLSLPKVIEYSLQNNGELKALREEKGVRDASKFRAGLLPNPTLD
LEAGTGALTGSSDENNLTIGVSQEFLLAGKRDKRLTVAERELEAYRWQLADRERTLREEVKAVFYDVMLAEQRLKLTDRS
IDLNRQLLEVTKDRLAAGDIPELEMNLAKVELTRSEGARIEVERALLQTRSRLFAFMGLPAGEAPAIAGTLDNGFSLNKN
LADLKQLALGLRPDLKALEAEKGRGDADITLAEAEKVPNLTAGLFYTHDRRTDATGTGEEKVRDNLLGIRLSMPIPVFDK
NQAGLQEARAKRSSSESRLTAATRIVERDVETAYISALNAEKVLSLYKSNIIPQLEENLKLTQEAYRLGEVGILSVIQEQ
KKFFEVSDGYLTALHDRQLALVKLESAVATDINGGVQ
>Mature_437_residues
MEVISLGTTVFARGALLLVPGIAVLLSSTLVRADEPSLSLPKVIEYSLQNNGELKALREEKGVRDASKFRAGLLPNPTLD
LEAGTGALTGSSDENNLTIGVSQEFLLAGKRDKRLTVAERELEAYRWQLADRERTLREEVKAVFYDVMLAEQRLKLTDRS
IDLNRQLLEVTKDRLAAGDIPELEMNLAKVELTRSEGARIEVERALLQTRSRLFAFMGLPAGEAPAIAGTLDNGFSLNKN
LADLKQLALGLRPDLKALEAEKGRGDADITLAEAEKVPNLTAGLFYTHDRRTDATGTGEEKVRDNLLGIRLSMPIPVFDK
NQAGLQEARAKRSSSESRLTAATRIVERDVETAYISALNAEKVLSLYKSNIIPQLEENLKLTQEAYRLGEVGILSVIQEQ
KKFFEVSDGYLTALHDRQLALVKLESAVATDINGGVQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48021; Mature: 48021

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVISLGTTVFARGALLLVPGIAVLLSSTLVRADEPSLSLPKVIEYSLQNNGELKALREE
CCEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEHHHHH
KGVRDASKFRAGLLPNPTLDLEAGTGALTGSSDENNLTIGVSQEFLLAGKRDKRLTVAER
CCCCCHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCHHHHHCCCCCCEEHHHHH
ELEAYRWQLADRERTLREEVKAVFYDVMLAEQRLKLTDRSIDLNRQLLEVTKDRLAAGDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
PELEMNLAKVELTRSEGARIEVERALLQTRSRLFAFMGLPAGEAPAIAGTLDNGFSLNKN
CHHHHHHEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCC
LADLKQLALGLRPDLKALEAEKGRGDADITLAEAEKVPNLTAGLFYTHDRRTDATGTGEE
HHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEHHHCCCCCEEEEEEEECCCCCCCCCCHH
KVRDNLLGIRLSMPIPVFDKNQAGLQEARAKRSSSESRLTAATRIVERDVETAYISALNA
HHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCH
EKVLSLYKSNIIPQLEENLKLTQEAYRLGEVGILSVIQEQKKFFEVSDGYLTALHDRQLA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCEEEEECCCCEE
LVKLESAVATDINGGVQ
EEEEHHHHHHCCCCCCC
>Mature Secondary Structure
MEVISLGTTVFARGALLLVPGIAVLLSSTLVRADEPSLSLPKVIEYSLQNNGELKALREE
CCEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEHHHHH
KGVRDASKFRAGLLPNPTLDLEAGTGALTGSSDENNLTIGVSQEFLLAGKRDKRLTVAER
CCCCCHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCHHHHHCCCCCCEEHHHHH
ELEAYRWQLADRERTLREEVKAVFYDVMLAEQRLKLTDRSIDLNRQLLEVTKDRLAAGDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
PELEMNLAKVELTRSEGARIEVERALLQTRSRLFAFMGLPAGEAPAIAGTLDNGFSLNKN
CHHHHHHEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCC
LADLKQLALGLRPDLKALEAEKGRGDADITLAEAEKVPNLTAGLFYTHDRRTDATGTGEE
HHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEHHHCCCCCEEEEEEEECCCCCCCCCCHH
KVRDNLLGIRLSMPIPVFDKNQAGLQEARAKRSSSESRLTAATRIVERDVETAYISALNA
HHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCH
EKVLSLYKSNIIPQLEENLKLTQEAYRLGEVGILSVIQEQKKFFEVSDGYLTALHDRQLA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCEEEEECCCCEE
LVKLESAVATDINGGVQ
EEEEHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]