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The map label for this gene is tig

Identifier: 39996892

GI number: 39996892

Start: 1958330

End: 1959625

Strand: Reverse

Name: tig

Synonym: GSU1793

Alternate gene names: 39996892

Gene position: 1959625-1958330 (Counterclockwise)

Preceding gene: 39996893

Following gene: 39996891

Centisome position: 51.38

GC content: 51.47

Gene sequence:

>1296_bases
ATGACCAGCACTGTCGAGTCGCTCAGCAGCGTCAAAAAGAAAATTTCCTTTGAGATTCCGGCGGACCGCGTTACGTCCGA
GATAGACAAGGTTTTTGAAAAGATCCGCAAGCGCGCGGCCATTAAGGGCTTCCGTAAAGGCAAAGCCCCCCAGTCACTCA
TTGAAAAGCATTATGCAGACGTCATGGAAGGTGACGTGCTGAAGAATCTGTTCGAGGAGACGTATTTCAAGGCGCTTGCC
GAGCACAAAATCTTTCCCGTTTCCCATCCAGTAATTGACAGCGACGAAATAAAGCGCGGAACTCCGTTTACCTACTCCGC
TACGGTCGAAGTTCTCCCCGAAATCGACGTAAAGGACTACAACGGACTTGAGGTTGCCAAGGAAACCTTCACGCCCGATG
AGTCGATTGTTGAGAAGAGACTGCAGGAAATGCGTGAGAACATGTCTCACCTGAGGTCTCTGGAAGAGGGATCAGTGGCT
GAAGATGGGCACTTCGCCGTCATTGACTTTACCGGTTACGTCGACGGTGTTCCGTTTGAAGGCGGCTCTGCCGAGAGTTA
CCAGCTTGAACTCGGTTCCGGCCGATTTATTCCCGGTTTTGAAGAACAGATCGTGGGTATGAAGACCGGCGAGTCGAAAT
CAATGTCGCTGAACTTTCCTGAGGACTACTGGAACAAAGATCTTGCCGGCAAAGAGGCCCGATTTGACGTGATCCTGAGT
GAGATCAAGGTCAAAGAGCTCCCTGAGCTGAATGATGAGTTTGCCGCTCAGATGGGAGAGTTCGATACCATCACCCAACT
GAGGGACAAGATTGCTGAACTGTACGAGAAGCAGGAAAACGACCGGATTAAAGCAGACCTTCAGGATCGGGTCGTGCAGG
CGCTCATTGAGAAAAACGAAATAGAGGTTCCTTCGACGCTTGTGGACCGGCAACTGCAGACCATGCTGGCCAACGCACAG
AACAGGCTTGCCCAGCAGCGGCTTACCTTCGAAATGATGGGAATGAACGAGGAGTCGTTCAAGGCCCAGTACCGTACCGT
TGCTGAGAACCAGGTCAAGGGTTCGCTTCTTCTTGAAGCCGTTGCCAAAAAAGAAGGAATTTCGGTCGAAGAGGCTGACA
TCGAGAAAAAACTGCTGGAAATTGCAGGAGGCAACGAGGAGGAGCTCGGCCGCGTAAAGAGCTTTTACGAGCAGAATCGT
GCGGCACGGGAAAATCTTGTAGCGCACTTGGCCGAGGAGAAGGTCATGTCGTTTCTTCTGGGTAGCGCAGTAATCAGCGA
GAAGACGAAAGAGTAA

Upstream 100 bases:

>100_bases
GCTTTCTTAATTACCCGCCCGGAGATTGTTGTTTTCTTGCCCACTATCCCGTCCGATTAATAATCATATTAACACTACCC
CAATGGAGAGAGGTTGAACG

Downstream 100 bases:

>100_bases
CCTGTGGAGCGAGGAGGCAACATGCTTGTACCGATAGTGGTCGAACAAACGGGTAGGGGTGAACGTTCCTACGATATTTA
TTCGAGGCTCCTGAAGGATC

Product: trigger factor

Products: peptidylproline (omega=0)

Alternate protein names: TF

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTSTVESLSSVKKKISFEIPADRVTSEIDKVFEKIRKRAAIKGFRKGKAPQSLIEKHYADVMEGDVLKNLFEETYFKALA
EHKIFPVSHPVIDSDEIKRGTPFTYSATVEVLPEIDVKDYNGLEVAKETFTPDESIVEKRLQEMRENMSHLRSLEEGSVA
EDGHFAVIDFTGYVDGVPFEGGSAESYQLELGSGRFIPGFEEQIVGMKTGESKSMSLNFPEDYWNKDLAGKEARFDVILS
EIKVKELPELNDEFAAQMGEFDTITQLRDKIAELYEKQENDRIKADLQDRVVQALIEKNEIEVPSTLVDRQLQTMLANAQ
NRLAQQRLTFEMMGMNEESFKAQYRTVAENQVKGSLLLEAVAKKEGISVEEADIEKKLLEIAGGNEEELGRVKSFYEQNR
AARENLVAHLAEEKVMSFLLGSAVISEKTKE

Sequences:

>Translated_431_residues
MTSTVESLSSVKKKISFEIPADRVTSEIDKVFEKIRKRAAIKGFRKGKAPQSLIEKHYADVMEGDVLKNLFEETYFKALA
EHKIFPVSHPVIDSDEIKRGTPFTYSATVEVLPEIDVKDYNGLEVAKETFTPDESIVEKRLQEMRENMSHLRSLEEGSVA
EDGHFAVIDFTGYVDGVPFEGGSAESYQLELGSGRFIPGFEEQIVGMKTGESKSMSLNFPEDYWNKDLAGKEARFDVILS
EIKVKELPELNDEFAAQMGEFDTITQLRDKIAELYEKQENDRIKADLQDRVVQALIEKNEIEVPSTLVDRQLQTMLANAQ
NRLAQQRLTFEMMGMNEESFKAQYRTVAENQVKGSLLLEAVAKKEGISVEEADIEKKLLEIAGGNEEELGRVKSFYEQNR
AARENLVAHLAEEKVMSFLLGSAVISEKTKE
>Mature_430_residues
TSTVESLSSVKKKISFEIPADRVTSEIDKVFEKIRKRAAIKGFRKGKAPQSLIEKHYADVMEGDVLKNLFEETYFKALAE
HKIFPVSHPVIDSDEIKRGTPFTYSATVEVLPEIDVKDYNGLEVAKETFTPDESIVEKRLQEMRENMSHLRSLEEGSVAE
DGHFAVIDFTGYVDGVPFEGGSAESYQLELGSGRFIPGFEEQIVGMKTGESKSMSLNFPEDYWNKDLAGKEARFDVILSE
IKVKELPELNDEFAAQMGEFDTITQLRDKIAELYEKQENDRIKADLQDRVVQALIEKNEIEVPSTLVDRQLQTMLANAQN
RLAQQRLTFEMMGMNEESFKAQYRTVAENQVKGSLLLEAVAKKEGISVEEADIEKKLLEIAGGNEEELGRVKSFYEQNRA
ARENLVAHLAEEKVMSFLLGSAVISEKTKE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=433, Percent_Identity=30.715935334873, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_GEOSL (Q74C81)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952843.1
- ProteinModelPortal:   Q74C81
- GeneID:   2685787
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1793
- NMPDR:   fig|243231.1.peg.1781
- TIGR:   GSU1793
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   CLSK828562
- BioCyc:   GSUL243231:GSU_1793-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: 5.2.1.8

Molecular weight: Translated: 48703; Mature: 48571

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTVESLSSVKKKISFEIPADRVTSEIDKVFEKIRKRAAIKGFRKGKAPQSLIEKHYAD
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VMEGDVLKNLFEETYFKALAEHKIFPVSHPVIDSDEIKRGTPFTYSATVEVLPEIDVKDY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCCCCCCC
NGLEVAKETFTPDESIVEKRLQEMRENMSHLRSLEEGSVAEDGHFAVIDFTGYVDGVPFE
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
GGSAESYQLELGSGRFIPGFEEQIVGMKTGESKSMSLNFPEDYWNKDLAGKEARFDVILS
CCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCEECCCCHHHCCCCCCCCHHHHHHHHH
EIKVKELPELNDEFAAQMGEFDTITQLRDKIAELYEKQENDRIKADLQDRVVQALIEKNE
HHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
IEVPSTLVDRQLQTMLANAQNRLAQQRLTFEMMGMNEESFKAQYRTVAENQVKGSLLLEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAKKEGISVEEADIEKKLLEIAGGNEEELGRVKSFYEQNRAARENLVAHLAEEKVMSFLL
HHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSAVISEKTKE
HHHHHHHCCCC
>Mature Secondary Structure 
TSTVESLSSVKKKISFEIPADRVTSEIDKVFEKIRKRAAIKGFRKGKAPQSLIEKHYAD
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VMEGDVLKNLFEETYFKALAEHKIFPVSHPVIDSDEIKRGTPFTYSATVEVLPEIDVKDY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCCCCCCC
NGLEVAKETFTPDESIVEKRLQEMRENMSHLRSLEEGSVAEDGHFAVIDFTGYVDGVPFE
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
GGSAESYQLELGSGRFIPGFEEQIVGMKTGESKSMSLNFPEDYWNKDLAGKEARFDVILS
CCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCEECCCCHHHCCCCCCCCHHHHHHHHH
EIKVKELPELNDEFAAQMGEFDTITQLRDKIAELYEKQENDRIKADLQDRVVQALIEKNE
HHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
IEVPSTLVDRQLQTMLANAQNRLAQQRLTFEMMGMNEESFKAQYRTVAENQVKGSLLLEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAKKEGISVEEADIEKKLLEIAGGNEEELGRVKSFYEQNRAARENLVAHLAEEKVMSFLL
HHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSAVISEKTKE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (omega=180)

Specific reaction: peptidylproline (omega=180) = peptidylproline (omega=0)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA