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The map label for this gene is yggV [C]

Identifier: 39996893

GI number: 39996893

Start: 1960195

End: 1960794

Strand: Reverse

Name: yggV [C]

Synonym: GSU1794

Alternate gene names: 39996893

Gene position: 1960794-1960195 (Counterclockwise)

Preceding gene: 39996894

Following gene: 39996892

Centisome position: 51.41

GC content: 55.17

Gene sequence:

>600_bases
GTGACCCGGCTGGTGGTAGCAACCCGCAACAAGGGTAAACTGCGAGAGATTGCTGCGATTCTGGACGGGTTGCCTTTCAC
GTTGTTGTCGCTCGAGGATTTCCCGGATTTCCCCGAAGTGGAAGAGGACGGCAAGACATTTGAAGAGAACGCCTTGAAAA
AGGCTTCAGTTGCCGCCAATATTACAGGACTTCCTGCGCTCGCCGATGACTCGGGGCTCGTCGTTGACGCACTTGATGGA
AAGCCGGGTGTTTACTCTGCCCGCTACTCGGGTGAGAACGCCAGCGACGAAGCAAATAATGCGAAGCTGTTGAGTGAGTT
GGAATCAGTGCCTTACGAAGAACGCACGGCCGCTTTCCGGTGCACCATCGCCCTGTGTTCGCCCGGAGGAAAGAGATACA
CCTTCAGCGGGGAACTGCATGGGGTAATCCTTGATTCGCCGCGCGGTACCGGAGGGTTCGGCTATGATCCTCTCTTTTTC
GTTTCCGAAAAAGGTGCAACCATGGCAGAACTCCCTCTTGAGGCCAAAAATGCCGTGAGTCACCGCGGCAGAGCCCTGGC
TCTTCTGAAAGATCATCTTGGCTGGCAGGGGATTGAATAA

Upstream 100 bases:

>100_bases
AGGCTGAACCTTTTACCTGCGCCCAGATGGATGATATGCGCTCCCTTGCCATGATCGGCATCGAACGTCTCATGGCCATT
CAACAAGAGGTGCTTGAGCA

Downstream 100 bases:

>100_bases
AAATACTTGCATGTCAGTACGGCATGTGTTAGTTATACAAATTCCAACGGGGTGTAGCGCAGCCTGGCTAGCGCACCTGC
CTTGGGAGCAGGGGGTCGGA

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTRLVVATRNKGKLREIAAILDGLPFTLLSLEDFPDFPEVEEDGKTFEENALKKASVAANITGLPALADDSGLVVDALDG
KPGVYSARYSGENASDEANNAKLLSELESVPYEERTAAFRCTIALCSPGGKRYTFSGELHGVILDSPRGTGGFGYDPLFF
VSEKGATMAELPLEAKNAVSHRGRALALLKDHLGWQGIE

Sequences:

>Translated_199_residues
MTRLVVATRNKGKLREIAAILDGLPFTLLSLEDFPDFPEVEEDGKTFEENALKKASVAANITGLPALADDSGLVVDALDG
KPGVYSARYSGENASDEANNAKLLSELESVPYEERTAAFRCTIALCSPGGKRYTFSGELHGVILDSPRGTGGFGYDPLFF
VSEKGATMAELPLEAKNAVSHRGRALALLKDHLGWQGIE
>Mature_198_residues
TRLVVATRNKGKLREIAAILDGLPFTLLSLEDFPDFPEVEEDGKTFEENALKKASVAANITGLPALADDSGLVVDALDGK
PGVYSARYSGENASDEANNAKLLSELESVPYEERTAAFRCTIALCSPGGKRYTFSGELHGVILDSPRGTGGFGYDPLFFV
SEKGATMAELPLEAKNAVSHRGRALALLKDHLGWQGIE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=195, Percent_Identity=33.8461538461538, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI31657144, Length=175, Percent_Identity=33.1428571428571, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=48.7179487179487, Blast_Score=173, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322529, Length=196, Percent_Identity=32.6530612244898, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920712, Length=192, Percent_Identity=36.4583333333333, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_GEOSL (Q74C80)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952844.1
- ProteinModelPortal:   Q74C80
- SMR:   Q74C80
- GeneID:   2686352
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1794
- NMPDR:   fig|243231.1.peg.1782
- TIGR:   GSU1794
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- ProtClustDB:   PRK14822
- BioCyc:   GSUL243231:GSU_1794-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21317; Mature: 21186

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLVVATRNKGKLREIAAILDGLPFTLLSLEDFPDFPEVEEDGKTFEENALKKASVAAN
CCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEC
ITGLPALADDSGLVVDALDGKPGVYSARYSGENASDEANNAKLLSELESVPYEERTAAFR
CCCCCEEECCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEE
CTIALCSPGGKRYTFSGELHGVILDSPRGTGGFGYDPLFFVSEKGATMAELPLEAKNAVS
EEEEEECCCCCEEEECCCEEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHH
HRGRALALLKDHLGWQGIE
HCCCEEEEEHHHCCCCCCC
>Mature Secondary Structure 
TRLVVATRNKGKLREIAAILDGLPFTLLSLEDFPDFPEVEEDGKTFEENALKKASVAAN
CEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEC
ITGLPALADDSGLVVDALDGKPGVYSARYSGENASDEANNAKLLSELESVPYEERTAAFR
CCCCCEEECCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEE
CTIALCSPGGKRYTFSGELHGVILDSPRGTGGFGYDPLFFVSEKGATMAELPLEAKNAVS
EEEEEECCCCCEEEECCCEEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHH
HRGRALALLKDHLGWQGIE
HCCCEEEEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA