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The map label for this gene is clpX [H]

Identifier: 39996890

GI number: 39996890

Start: 1956459

End: 1957712

Strand: Reverse

Name: clpX [H]

Synonym: GSU1791

Alternate gene names: 39996890

Gene position: 1957712-1956459 (Counterclockwise)

Preceding gene: 39996891

Following gene: 39996889

Centisome position: 51.33

GC content: 51.36

Gene sequence:

>1254_bases
GTGAGTAGGAGAAACGACGGCAGCGACAATCTCACCTGCTCCTTTTGTGGTAAGAGCCAGGATGAAGTAAAAAAGCTCAT
TGCCGGACCAACGGTATATATTTGCGACGAGTGCATCGAACTCTGTAATGATATTATTGCCGAGGAGTCGAAGCTTGAAG
AGGCCATGGGGCCCGATGTCAAGAAGCTTCCCAAACCCCGTGAAATCAAGGATGTTCTCGACGAATACGTGATTGGCCAG
GACCAAGCGAAAAAAGTCCTCGCCGTCGCTGTTTACAATCACTACAAGCGCATAGAGTCCATGGGCAAGCCGAGCGATGT
AGAGATGCAGAAGAGCAACATTCTTCTGCTTGGACCTACTGGCTCCGGCAAGACCCTGTTGGCTCAGACCCTGGCCCGGA
TACTGAAAGTTCCGTTCGCCATGGCGGATGCTACAAACCTCACTGAAGCCGGCTATGTGGGGGAAGATGTCGAGAATATC
ATTCTCAATCTTCTTCAGGCTGCCGACTATGATGTAGAACGGGCCCAGAAGGGTATCATCTATATCGACGAAATTGACAA
GATAGCCCGTAAATCCGATTCTCCATCCATCACCCGGGATGTGTCGGGGGAAGGGGTGCAGCAGGCGCTGTTGAAAATTA
TTGAAGGAACCGTCGCCAGCGTTCCTCCCAAGGGAGGACGCAAGCACCCGCAGCAAGAGTTTTTGAAGGTCGATACCACG
AATATTCTGTTTATCTGCGGCGGCGCGTTCGCGGGGCTCGACAGCATTATTCAGCAGCGTATCGGTGTGAAAAAGCTCGG
TTTCGGTGCTGACGTAAAGAGCAAAGTCGAGAAGAGAGCAGGAGAGCTTCTCACGGAAGTTACCCCTGAAGACCTTCTCA
AGTTCGGTTTCATCCCAGAATTCATCGGTCGTCTGCCCGTCCTCGCTACCCTGCGCGAACTGGATGAAACCGCTATGGTC
CAGATCCTGAAGGAGCCGAAAAACGCGCTTATCAAGCAATACCAGAAGCTGTTCGAAATGGAGCATGTGAAGCTCAAGTT
TACCGACGGTTCTCTGGTCGCCATATCCCGGGAAGCGCTCAAGCGTAAGACGGGCGCCCGCGGACTCCGGTCGATCCTTG
AGAACGCCATGCTTGACATCATGTATGAAATTCCATCGCAAACCATGGTTAAAGAAGTGGTCATCAACGAAGATGTCATC
TACAACAAGGAAAAGCCGATCATTGTTTATGAAAATGTGGCTGAGTCAGCCTGA

Upstream 100 bases:

>100_bases
CCGATACCGAGCGCGACTATTTTATGTCTGGAGCGGAGGCGAAGGACTATGGTATCATTGATAACATAATTGAGCGCAAT
ACTCCCAGCGGAGGTACTCG

Downstream 100 bases:

>100_bases
CTGCAAAGGACCCAATGAGCGTCGACCATAGTATAGAAAGCCTGGAAAGAGGGGATCTGCAAAGATTCCCTCTTTTACCG
TTAAGGGACATTGTTGTTTT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSRRNDGSDNLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDVKKLPKPREIKDVLDEYVIGQ
DQAKKVLAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPTGSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENI
ILNLLQAADYDVERAQKGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTT
NILFICGGAFAGLDSIIQQRIGVKKLGFGADVKSKVEKRAGELLTEVTPEDLLKFGFIPEFIGRLPVLATLRELDETAMV
QILKEPKNALIKQYQKLFEMEHVKLKFTDGSLVAISREALKRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVINEDVI
YNKEKPIIVYENVAESA

Sequences:

>Translated_417_residues
MSRRNDGSDNLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDVKKLPKPREIKDVLDEYVIGQ
DQAKKVLAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPTGSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENI
ILNLLQAADYDVERAQKGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTT
NILFICGGAFAGLDSIIQQRIGVKKLGFGADVKSKVEKRAGELLTEVTPEDLLKFGFIPEFIGRLPVLATLRELDETAMV
QILKEPKNALIKQYQKLFEMEHVKLKFTDGSLVAISREALKRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVINEDVI
YNKEKPIIVYENVAESA
>Mature_416_residues
SRRNDGSDNLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDVKKLPKPREIKDVLDEYVIGQD
QAKKVLAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPTGSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENII
LNLLQAADYDVERAQKGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTTN
ILFICGGAFAGLDSIIQQRIGVKKLGFGADVKSKVEKRAGELLTEVTPEDLLKFGFIPEFIGRLPVLATLRELDETAMVQ
ILKEPKNALIKQYQKLFEMEHVKLKFTDGSLVAISREALKRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVINEDVIY
NKEKPIIVYENVAESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=336, Percent_Identity=50.8928571428571, Blast_Score=315, Evalue=4e-86,
Organism=Escherichia coli, GI1786642, Length=411, Percent_Identity=69.0997566909976, Blast_Score=571, Evalue=1e-164,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=44.6601941747573, Blast_Score=95, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=328, Percent_Identity=45.4268292682927, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=328, Percent_Identity=45.4268292682927, Blast_Score=277, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=428, Percent_Identity=37.8504672897196, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=39.5348837209302, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=424, Percent_Identity=41.2735849056604, Blast_Score=272, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24648291, Length=319, Percent_Identity=47.0219435736677, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24648289, Length=319, Percent_Identity=47.0219435736677, Blast_Score=294, Evalue=6e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46130; Mature: 45999

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRNDGSDNLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDV
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KKLPKPREIKDVLDEYVIGQDQAKKVLAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPT
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECCC
GSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENIILNLLQAADYDVERAQKGII
CCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTT
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCC
NILFICGGAFAGLDSIIQQRIGVKKLGFGADVKSKVEKRAGELLTEVTPEDLLKFGFIPE
CEEEEECCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHH
FIGRLPVLATLRELDETAMVQILKEPKNALIKQYQKLFEMEHVKLKFTDGSLVAISREAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEHHHHHH
KRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVINEDVIYNKEKPIIVYENVAESA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCCCCCC
>Mature Secondary Structure 
SRRNDGSDNLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDV
CCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KKLPKPREIKDVLDEYVIGQDQAKKVLAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPT
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECCC
GSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENIILNLLQAADYDVERAQKGII
CCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTT
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCC
NILFICGGAFAGLDSIIQQRIGVKKLGFGADVKSKVEKRAGELLTEVTPEDLLKFGFIPE
CEEEEECCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHH
FIGRLPVLATLRELDETAMVQILKEPKNALIKQYQKLFEMEHVKLKFTDGSLVAISREAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEHHHHHH
KRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVINEDVIYNKEKPIIVYENVAESA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA