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The map label for this gene is ftsX [H]

Identifier: 39996873

GI number: 39996873

Start: 1938190

End: 1939140

Strand: Reverse

Name: ftsX [H]

Synonym: GSU1774

Alternate gene names: 39996873

Gene position: 1939140-1938190 (Counterclockwise)

Preceding gene: 39996874

Following gene: 39996872

Centisome position: 50.84

GC content: 53.31

Gene sequence:

>951_bases
ATGTCCCGAAACAAGAACTCTAAGCGGCCCACCCTTTCCGGCGATGCTCCCGGGGGGCGGCTCGGCTATTTTCTCGGCAG
GGCGATCCTCAATCTTCGTCAGAATGTCATGGTGAACGTGTTGACAATCGGCACCATATCGCTGGCTCTGCTTATCGTCT
CACTGTTTCTGCTGGTGTTCGTAAACCTCGAGTCAACTGCCGAGGAGTGGAGCGGCAAGATCCAGGTTACCGCCTATTTC
GACCAGGAACTGCCCCCCCAGGAGCTAAACCAGCTCATGAATCGCATCAAAGCGATTGAAGGGACTTCACGCGTTTCCTA
CGTGAATAAGAACGAGGCGATGAAGCGGTTCAGATCCAGACTGAAGGGGCAGGAAACCCTCCTGGACGGCGTACCTGCCG
ACGTGTTGCCTGCTTCGGTGGAGATTGCCCTTAAACGGTCCAGCCGCCAGGAAGGTGCAATTGAACACTACGTTGCCCAG
CTTAAAAAGGTCCCCGGAATCAATGAGGTGCAATATGGGGAAGAATGGGTCCGCCGTTTCAATGCCTTTATGAATTTTCT
CCGTTTTCTCGGAGCGCTTTTAGGGGCGTTCCTTGTGCTGGCGGTACTGTTCATCGTTTCCAATACGATCAGACTTACCA
TCTACGCCCGGAAGGATGAACTGGAGGTTATGGAACTGGTAGGTGCCACGCGGTTTTTTATCAAGGCGCCGTTTCTCGTG
GAAGGGATGATTCAGGGCGCTGCCGGTTCAATTTGCACACTTATCATTCTTGTTGCCGCCTACTTTGGCTTCTTGCACGG
TGTACCTAACTTTATCCCCATATCAGGTACCTTTACCGGGTTCTCTTTCCTGCCCCCGGTACATATTGCCGGTATTTTCA
TCGGCGGCATCGTGCTCGGGCTTCTTGGCAGTCTCACCTCGCTCAGGCGTTTCAGCGACAATCAGTCATGA

Upstream 100 bases:

>100_bases
GGTACGACCGTCATGGTTGCGACTCACGACCGGCGAGTGATCGAAAACAGCCACAAGCGGGTGATCATCCTGGATAAGGG
GCGCCTGGTGGAGGATAACG

Downstream 100 bases:

>100_bases
TGCGAAGTTTTTGGGTACCCATAGTATTTCTGACGATCTGCGTTTCCGTAGCGCTTGCCGCTGATGTGCACGATCAACTC
AAGGGCGTGAAGAAGGAAAT

Product: cell division ABC transporter permease FtsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSRNKNSKRPTLSGDAPGGRLGYFLGRAILNLRQNVMVNVLTIGTISLALLIVSLFLLVFVNLESTAEEWSGKIQVTAYF
DQELPPQELNQLMNRIKAIEGTSRVSYVNKNEAMKRFRSRLKGQETLLDGVPADVLPASVEIALKRSSRQEGAIEHYVAQ
LKKVPGINEVQYGEEWVRRFNAFMNFLRFLGALLGAFLVLAVLFIVSNTIRLTIYARKDELEVMELVGATRFFIKAPFLV
EGMIQGAAGSICTLIILVAAYFGFLHGVPNFIPISGTFTGFSFLPPVHIAGIFIGGIVLGLLGSLTSLRRFSDNQS

Sequences:

>Translated_316_residues
MSRNKNSKRPTLSGDAPGGRLGYFLGRAILNLRQNVMVNVLTIGTISLALLIVSLFLLVFVNLESTAEEWSGKIQVTAYF
DQELPPQELNQLMNRIKAIEGTSRVSYVNKNEAMKRFRSRLKGQETLLDGVPADVLPASVEIALKRSSRQEGAIEHYVAQ
LKKVPGINEVQYGEEWVRRFNAFMNFLRFLGALLGAFLVLAVLFIVSNTIRLTIYARKDELEVMELVGATRFFIKAPFLV
EGMIQGAAGSICTLIILVAAYFGFLHGVPNFIPISGTFTGFSFLPPVHIAGIFIGGIVLGLLGSLTSLRRFSDNQS
>Mature_315_residues
SRNKNSKRPTLSGDAPGGRLGYFLGRAILNLRQNVMVNVLTIGTISLALLIVSLFLLVFVNLESTAEEWSGKIQVTAYFD
QELPPQELNQLMNRIKAIEGTSRVSYVNKNEAMKRFRSRLKGQETLLDGVPADVLPASVEIALKRSSRQEGAIEHYVAQL
KKVPGINEVQYGEEWVRRFNAFMNFLRFLGALLGAFLVLAVLFIVSNTIRLTIYARKDELEVMELVGATRFFIKAPFLVE
GMIQGAAGSICTLIILVAAYFGFLHGVPNFIPISGTFTGFSFLPPVHIAGIFIGGIVLGLLGSLTSLRRFSDNQS

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=228, Percent_Identity=26.7543859649123, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 34874; Mature: 34743

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNKNSKRPTLSGDAPGGRLGYFLGRAILNLRQNVMVNVLTIGTISLALLIVSLFLLVF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNLESTAEEWSGKIQVTAYFDQELPPQELNQLMNRIKAIEGTSRVSYVNKNEAMKRFRSR
HCCHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHH
LKGQETLLDGVPADVLPASVEIALKRSSRQEGAIEHYVAQLKKVPGINEVQYGEEWVRRF
HCCHHHHHCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
NAFMNFLRFLGALLGAFLVLAVLFIVSNTIRLTIYARKDELEVMELVGATRFFIKAPFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHH
EGMIQGAAGSICTLIILVAAYFGFLHGVPNFIPISGTFTGFSFLPPVHIAGIFIGGIVLG
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
LLGSLTSLRRFSDNQS
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRNKNSKRPTLSGDAPGGRLGYFLGRAILNLRQNVMVNVLTIGTISLALLIVSLFLLVF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNLESTAEEWSGKIQVTAYFDQELPPQELNQLMNRIKAIEGTSRVSYVNKNEAMKRFRSR
HCCHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHH
LKGQETLLDGVPADVLPASVEIALKRSSRQEGAIEHYVAQLKKVPGINEVQYGEEWVRRF
HCCHHHHHCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
NAFMNFLRFLGALLGAFLVLAVLFIVSNTIRLTIYARKDELEVMELVGATRFFIKAPFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHH
EGMIQGAAGSICTLIILVAAYFGFLHGVPNFIPISGTFTGFSFLPPVHIAGIFIGGIVLG
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
LLGSLTSLRRFSDNQS
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]