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The map label for this gene is aroB [H]

Identifier: 39996840

GI number: 39996840

Start: 1905995

End: 1906918

Strand: Reverse

Name: aroB [H]

Synonym: GSU1741

Alternate gene names: 39996840

Gene position: 1906918-1905995 (Counterclockwise)

Preceding gene: 39996841

Following gene: 39996838

Centisome position: 50.0

GC content: 63.31

Gene sequence:

>924_bases
ATGTCGTTCCCTGCAGCCTCCATCGATCTTGGCACCAATACGGCCCGGCTTCTGATCGGATCAGTAGAGGCGGGCCGGAT
CGAGCACCTGCTCGTAAAGCGCCACATCACCCGGTTGGGTGGAGGGTTTACAAAGGAACGGGGGATTTCGCCGGAGGCGT
GGAGCCGCTCACTGGCCGCTCTTGTCGACTTTGCGGATGAAATGAACCGCGCGGGAGTCGTCCGTGTGCGGGCCGTAGCG
ACCAGCGCGGTTCGGGACGCCGTGAACGGCGGGGATTTTTGCGCCGACGTGGCCGAGCGGACCGGCATCAGTCTGGAAGT
GATCGACGGCGAAGAGGAGGCTCTTCTGACTCTGGCGGGGGTCCTGTCGGGCCTTGACCGGAAGGAGGGCCGCTTCTTCG
TTTTTGACGTGGGGGGAGGGAGCACTGAATACACCCTTGCCAGCGGGAACGCTCCTCTGTACACCGAGAGTCTTCCCCTG
GGGGTGGTGAGATTGACGGAAGGCAAGTCCGACCTGCCGGCCATGGAGGAGAAAGTCGGGCGCGAACTCGCCGGGCTCAG
GGAACGGCTGGCCGGCAGGGCACTCGATGGACAGCTTGCGGGAGCGACGCTCGTGGGCACCGCCGGCACGGCAACGACCC
TGGCAGCCATCAGTCTGGGAATGACCGATTACGATTATCGGCGAGTCAACAACCACCTGTTGTCCCGTGATGAAATCGCG
CGTATTCTGGCCCTGCTTCTTCCCCTTTCCCCGGCCGAACGCCTGGCGGTGCCCGGCCTGGAAAAGGGGAGGGAGGATCT
GATCGTGGCCGGAACGCTCATAACACTCGCCACGATGGACCTGTTCGGCTTCGAATCCATGACCGTCAGCGACTTCGGCT
TGCTGGAAGGTGCCCTGATCGGCCTTGCCCGCACGGATGAATAG

Upstream 100 bases:

>100_bases
CCGTTCGTGCAGGAATCATCTACGCTGATATGATTACGGCCTTTGTCAAAATCGCCGATTCAAGTGTCACCATCATTGAA
ACCAGGAAGGAGTTCACCTG

Downstream 100 bases:

>100_bases
ATTAGCCCCCGGGATTCCCAAAGCTCCTGATGTGCTGCATAAGGGCCTTCATGTCTTCTCCGCCCGGGTCGAGCGGTTTC
CCCTTGAGGGCCTTTTCGAT

Product: Ppx/GppA family phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSFPAASIDLGTNTARLLIGSVEAGRIEHLLVKRHITRLGGGFTKERGISPEAWSRSLAALVDFADEMNRAGVVRVRAVA
TSAVRDAVNGGDFCADVAERTGISLEVIDGEEEALLTLAGVLSGLDRKEGRFFVFDVGGGSTEYTLASGNAPLYTESLPL
GVVRLTEGKSDLPAMEEKVGRELAGLRERLAGRALDGQLAGATLVGTAGTATTLAAISLGMTDYDYRRVNNHLLSRDEIA
RILALLLPLSPAERLAVPGLEKGREDLIVAGTLITLATMDLFGFESMTVSDFGLLEGALIGLARTDE

Sequences:

>Translated_307_residues
MSFPAASIDLGTNTARLLIGSVEAGRIEHLLVKRHITRLGGGFTKERGISPEAWSRSLAALVDFADEMNRAGVVRVRAVA
TSAVRDAVNGGDFCADVAERTGISLEVIDGEEEALLTLAGVLSGLDRKEGRFFVFDVGGGSTEYTLASGNAPLYTESLPL
GVVRLTEGKSDLPAMEEKVGRELAGLRERLAGRALDGQLAGATLVGTAGTATTLAAISLGMTDYDYRRVNNHLLSRDEIA
RILALLLPLSPAERLAVPGLEKGREDLIVAGTLITLATMDLFGFESMTVSDFGLLEGALIGLARTDE
>Mature_306_residues
SFPAASIDLGTNTARLLIGSVEAGRIEHLLVKRHITRLGGGFTKERGISPEAWSRSLAALVDFADEMNRAGVVRVRAVAT
SAVRDAVNGGDFCADVAERTGISLEVIDGEEEALLTLAGVLSGLDRKEGRFFVFDVGGGSTEYTLASGNAPLYTESLPLG
VVRLTEGKSDLPAMEEKVGRELAGLRERLAGRALDGQLAGATLVGTAGTATTLAAISLGMTDYDYRRVNNHLLSRDEIAR
ILALLLPLSPAERLAVPGLEKGREDLIVAGTLITLATMDLFGFESMTVSDFGLLEGALIGLARTDE

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=308, Percent_Identity=29.8701298701299, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788848, Length=298, Percent_Identity=25.8389261744966, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32413; Mature: 32282

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPAASIDLGTNTARLLIGSVEAGRIEHLLVKRHITRLGGGFTKERGISPEAWSRSLAA
CCCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LVDFADEMNRAGVVRVRAVATSAVRDAVNGGDFCADVAERTGISLEVIDGEEEALLTLAG
HHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHH
VLSGLDRKEGRFFVFDVGGGSTEYTLASGNAPLYTESLPLGVVRLTEGKSDLPAMEEKVG
HHHCCCCCCCCEEEEECCCCCEEEEEECCCCCEEECCCCCEEEEECCCCCCCCHHHHHHH
RELAGLRERLAGRALDGQLAGATLVGTAGTATTLAAISLGMTDYDYRRVNNHLLSRDEIA
HHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
RILALLLPLSPAERLAVPGLEKGREDLIVAGTLITLATMDLFGFESMTVSDFGLLEGALI
HHHHHHHCCCCHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHE
GLARTDE
EEEECCC
>Mature Secondary Structure 
SFPAASIDLGTNTARLLIGSVEAGRIEHLLVKRHITRLGGGFTKERGISPEAWSRSLAA
CCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LVDFADEMNRAGVVRVRAVATSAVRDAVNGGDFCADVAERTGISLEVIDGEEEALLTLAG
HHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHH
VLSGLDRKEGRFFVFDVGGGSTEYTLASGNAPLYTESLPLGVVRLTEGKSDLPAMEEKVG
HHHCCCCCCCCEEEEECCCCCEEEEEECCCCCEEECCCCCEEEEECCCCCCCCHHHHHHH
RELAGLRERLAGRALDGQLAGATLVGTAGTATTLAAISLGMTDYDYRRVNNHLLSRDEIA
HHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
RILALLLPLSPAERLAVPGLEKGREDLIVAGTLITLATMDLFGFESMTVSDFGLLEGALI
HHHHHHHCCCCHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHE
GLARTDE
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]