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The map label for this gene is nrdR

Identifier: 39996787

GI number: 39996787

Start: 1846792

End: 1847244

Strand: Direct

Name: nrdR

Synonym: GSU1687

Alternate gene names: 39996787

Gene position: 1846792-1847244 (Clockwise)

Preceding gene: 39996786

Following gene: 39996788

Centisome position: 48.42

GC content: 58.5

Gene sequence:

>453_bases
ATGAAATGTCCGTTCTGCGGTCAACTCGACAGCAAGGTGGTGGACTCGCGCCCCGATAAGGGTGGGGCGGCTATCCGCCG
CCGGCGCGAATGCGAGTCGTGCGGCAAGCGGTTCACAACCCACGAACGGATCGAGGAAGTCTTGCCCCTGGTACTCAAGA
AAGACGGACGCCGCGAGCCATTCGACCGGCTCAAGCTTATCGCAGGCATTCAGAAGGCCTGTGAAAAGCGACAGGTGTCC
CGGGAAACCATCGAACGGCTCGTGGACCGGCTGGAGGCCCGCCTGCCGGAACTCGGAGAAAAGGAAGTGCCGAGTACCAC
CATCGGTGAATGGGTCATGACCGAGCTCCATGACATAGATGAGGTGGCGTACGTCCGCTTTGCTTCGGTCTATCGTTCCT
TCAAGGATGTCAACGAGTTTATGTCCGAGCTCCAGGATCTTCTCAAGAAGTAG

Upstream 100 bases:

>100_bases
TCGTGTACGAAGAGGGATACTCGGATGACCTTGCCCGCGAGATGATCGGCGAATCCGGCGTAGCAGTGGAGCGTTTCTCG
GACTTGAAAGGAAGAGCGTC

Downstream 100 bases:

>100_bases
CAGTCTCACTCCCAATCCCATGACATCTTTTCATGAAAACATGATGCGGCGTGCCCTTTCTCTCGCCCGGAAAGGCATTG
GCAAGACATCCCCCAACCCT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKCPFCGQLDSKVVDSRPDKGGAAIRRRRECESCGKRFTTHERIEEVLPLVLKKDGRREPFDRLKLIAGIQKACEKRQVS
RETIERLVDRLEARLPELGEKEVPSTTIGEWVMTELHDIDEVAYVRFASVYRSFKDVNEFMSELQDLLKK

Sequences:

>Translated_150_residues
MKCPFCGQLDSKVVDSRPDKGGAAIRRRRECESCGKRFTTHERIEEVLPLVLKKDGRREPFDRLKLIAGIQKACEKRQVS
RETIERLVDRLEARLPELGEKEVPSTTIGEWVMTELHDIDEVAYVRFASVYRSFKDVNEFMSELQDLLKK
>Mature_150_residues
MKCPFCGQLDSKVVDSRPDKGGAAIRRRRECESCGKRFTTHERIEEVLPLVLKKDGRREPFDRLKLIAGIQKACEKRQVS
RETIERLVDRLEARLPELGEKEVPSTTIGEWVMTELHDIDEVAYVRFASVYRSFKDVNEFMSELQDLLKK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=48.9795918367347, Blast_Score=147, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_GEOSL (Q74CI6)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952738.1
- GeneID:   2685213
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1687
- NMPDR:   fig|243231.1.peg.1676
- TIGR:   GSU1687
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   GSUL243231:GSU_1687-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17426; Mature: 17426

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCGQLDSKVVDSRPDKGGAAIRRRRECESCGKRFTTHERIEEVLPLVLKKDGRREP
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCH
FDRLKLIAGIQKACEKRQVSRETIERLVDRLEARLPELGEKEVPSTTIGEWVMTELHDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EVAYVRFASVYRSFKDVNEFMSELQDLLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKCPFCGQLDSKVVDSRPDKGGAAIRRRRECESCGKRFTTHERIEEVLPLVLKKDGRREP
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCH
FDRLKLIAGIQKACEKRQVSRETIERLVDRLEARLPELGEKEVPSTTIGEWVMTELHDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EVAYVRFASVYRSFKDVNEFMSELQDLLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA