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The map label for this gene is yegE [H]

Identifier: 39996756

GI number: 39996756

Start: 1815737

End: 1816999

Strand: Reverse

Name: yegE [H]

Synonym: GSU1656

Alternate gene names: 39996756

Gene position: 1816999-1815737 (Counterclockwise)

Preceding gene: 39996761

Following gene: 39996755

Centisome position: 47.64

GC content: 53.44

Gene sequence:

>1263_bases
TTGCCCCCTCCGCTTCGTGTACTCATACTTGAAGACTCGGAAGATGATTACTTCCTCCTCGTGAGAGCTCTCAAGCGCGA
GTTCGATATCGTCCCCGAGCGGGTTGATTCGGAAGAGTCGCTCCGCGCCAATCTCTGCGAAAAGAGATGGGATATCGTAT
TGTCGGATTATTTCATGCCACAATTCGATGCCTTGGCTGCCTTAACCCTCATCCAGAGCATGAACCTGGATATCCCCTTC
ATCATCGTTTCGGGCAAAATCGGGGAATTTGAAGCGGTTAAAGCGATGAAAGCCGGCGCTCATGACTATATCATGAAGGG
CGATTATACCCGCCTGATCCCCGCTATCCGCCGAGAACTCCGCGAAGCCGTGATCCGGCAGGAACAACGTCGGACCGACC
ACGAACTCCGCGAACAACTCCACTTCCGACAGGCGCTGATTGACGCCATTCCCGCCCCTATCTACTTCATGGATACCACG
GGAATTTTCCTTGGCTGCAACAAGGCGTTCGAGGCATTTTCGGGCCACACTCAGGATGAAATCGTCGGGAAGACAATCTA
TGACCTGATGCCCCCCTCGCTCGCAAAGCACACTGACAGTGCGGACAGGGAGCTGTTCGAGCACGGTGGCATCCAGATCT
ACGAGAGTGTCATATCCTTTGCCGACGGTGCACTCCATGACGTGATCTTTTATAAAGCCACGTTCACCACAACAGAAAAA
AACATCGGCGGCCTTGTAGGGACCATCCTCGACATTACCGAAAGGAAGCAGACTGAGGAAAGACTTCGTTACATGAGCAC
CCACGACACACTGACGGGACTTTACAACCGAGCCTATTTTCAGGAAGAAATGGAGCGACTTGAGCAGGGAAGGCAATTCC
CGGTCAGCGTAGTCGTATTTGACGTGGACCGGCTGAAATACGTCAATGACAGCCAGGGACACGCTGCGGGGGACGAATTG
CTGATTCGAGCTGCCTTGGTGCTCAAAGGCGCCTTCCGTGCCGAAGACGTGGTGGCGAGAATAGGAGGAGACGAATTCGC
CGTTCTCCTTCCCTCAGCAGACGCCGATGTAGTGCAGGAAGCCCTGCGAAGAGTGATTGGCAAAATAGAGCAGAGCCAGA
CGGAAGACCATCCTGTTCCCCTCAGTATCTCTTTCGGCGCTGCAACGGCCAGCAAGGGCGACCGCCTCGAAGAGGTACTC
AAGCTTGCCGACCGTAGAATGTACGAGAATAAGTTTAAAAAATGCTGCGTATTACCTGCATAA

Upstream 100 bases:

>100_bases
TTGGAATGTTATTACTATATACATAAAGAAAATGCGTGGGATATCAGAAGTCATTTGCAGCGTGTCGCCAGTGCCGGACT
CAGGCACCATGGAGTCTTTT

Downstream 100 bases:

>100_bases
ATTGCACTCATGCTGTCTCCTTCCCCGTTAAATAGACAGCTGTTGGGCCATACAAATGGATCGACAGTGCTAAACGTATC
CTGATTTTTGCCGATGAGAC

Product: sensory box/response regulator

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MPPPLRVLILEDSEDDYFLLVRALKREFDIVPERVDSEESLRANLCEKRWDIVLSDYFMPQFDALAALTLIQSMNLDIPF
IIVSGKIGEFEAVKAMKAGAHDYIMKGDYTRLIPAIRRELREAVIRQEQRRTDHELREQLHFRQALIDAIPAPIYFMDTT
GIFLGCNKAFEAFSGHTQDEIVGKTIYDLMPPSLAKHTDSADRELFEHGGIQIYESVISFADGALHDVIFYKATFTTTEK
NIGGLVGTILDITERKQTEERLRYMSTHDTLTGLYNRAYFQEEMERLEQGRQFPVSVVVFDVDRLKYVNDSQGHAAGDEL
LIRAALVLKGAFRAEDVVARIGGDEFAVLLPSADADVVQEALRRVIGKIEQSQTEDHPVPLSISFGAATASKGDRLEEVL
KLADRRMYENKFKKCCVLPA

Sequences:

>Translated_420_residues
MPPPLRVLILEDSEDDYFLLVRALKREFDIVPERVDSEESLRANLCEKRWDIVLSDYFMPQFDALAALTLIQSMNLDIPF
IIVSGKIGEFEAVKAMKAGAHDYIMKGDYTRLIPAIRRELREAVIRQEQRRTDHELREQLHFRQALIDAIPAPIYFMDTT
GIFLGCNKAFEAFSGHTQDEIVGKTIYDLMPPSLAKHTDSADRELFEHGGIQIYESVISFADGALHDVIFYKATFTTTEK
NIGGLVGTILDITERKQTEERLRYMSTHDTLTGLYNRAYFQEEMERLEQGRQFPVSVVVFDVDRLKYVNDSQGHAAGDEL
LIRAALVLKGAFRAEDVVARIGGDEFAVLLPSADADVVQEALRRVIGKIEQSQTEDHPVPLSISFGAATASKGDRLEEVL
KLADRRMYENKFKKCCVLPA
>Mature_419_residues
PPPLRVLILEDSEDDYFLLVRALKREFDIVPERVDSEESLRANLCEKRWDIVLSDYFMPQFDALAALTLIQSMNLDIPFI
IVSGKIGEFEAVKAMKAGAHDYIMKGDYTRLIPAIRRELREAVIRQEQRRTDHELREQLHFRQALIDAIPAPIYFMDTTG
IFLGCNKAFEAFSGHTQDEIVGKTIYDLMPPSLAKHTDSADRELFEHGGIQIYESVISFADGALHDVIFYKATFTTTEKN
IGGLVGTILDITERKQTEERLRYMSTHDTLTGLYNRAYFQEEMERLEQGRQFPVSVVVFDVDRLKYVNDSQGHAAGDELL
IRAALVLKGAFRAEDVVARIGGDEFAVLLPSADADVVQEALRRVIGKIEQSQTEDHPVPLSISFGAATASKGDRLEEVLK
LADRRMYENKFKKCCVLPA

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=264, Percent_Identity=30.3030303030303, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=37.9746835443038, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787541, Length=289, Percent_Identity=27.681660899654, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87081881, Length=272, Percent_Identity=28.3088235294118, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=33.9393939393939, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787262, Length=150, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=31.055900621118, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=152, Percent_Identity=32.2368421052632, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=172, Percent_Identity=29.6511627906977, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788956, Length=156, Percent_Identity=33.974358974359, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=150, Percent_Identity=30.6666666666667, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787056, Length=144, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994928, Length=144, Percent_Identity=27.0833333333333, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 47584; Mature: 47453

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPPLRVLILEDSEDDYFLLVRALKREFDIVPERVDSEESLRANLCEKRWDIVLSDYFMP
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QFDALAALTLIQSMNLDIPFIIVSGKIGEFEAVKAMKAGAHDYIMKGDYTRLIPAIRREL
HHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCHHEECCCHHHHHHHHHHHH
REAVIRQEQRRTDHELREQLHFRQALIDAIPAPIYFMDTTGIFLGCNKAFEAFSGHTQDE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCHHHHHHCCCCHHH
IVGKTIYDLMPPSLAKHTDSADRELFEHGGIQIYESVISFADGALHDVIFYKATFTTTEK
HHHHHHHHHCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHEEEEEEEECCH
NIGGLVGTILDITERKQTEERLRYMSTHDTLTGLYNRAYFQEEMERLEQGRQFPVSVVVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
DVDRLKYVNDSQGHAAGDELLIRAALVLKGAFRAEDVVARIGGDEFAVLLPSADADVVQE
EHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
ALRRVIGKIEQSQTEDHPVPLSISFGAATASKGDRLEEVLKLADRRMYENKFKKCCVLPA
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PPPLRVLILEDSEDDYFLLVRALKREFDIVPERVDSEESLRANLCEKRWDIVLSDYFMP
CCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QFDALAALTLIQSMNLDIPFIIVSGKIGEFEAVKAMKAGAHDYIMKGDYTRLIPAIRREL
HHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCHHEECCCHHHHHHHHHHHH
REAVIRQEQRRTDHELREQLHFRQALIDAIPAPIYFMDTTGIFLGCNKAFEAFSGHTQDE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCHHHHHHCCCCHHH
IVGKTIYDLMPPSLAKHTDSADRELFEHGGIQIYESVISFADGALHDVIFYKATFTTTEK
HHHHHHHHHCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHEEEEEEEECCH
NIGGLVGTILDITERKQTEERLRYMSTHDTLTGLYNRAYFQEEMERLEQGRQFPVSVVVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
DVDRLKYVNDSQGHAAGDELLIRAALVLKGAFRAEDVVARIGGDEFAVLLPSADADVVQE
EHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
ALRRVIGKIEQSQTEDHPVPLSISFGAATASKGDRLEEVLKLADRRMYENKFKKCCVLPA
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]