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The map label for this gene is bioD [H]

Identifier: 39996683

GI number: 39996683

Start: 1736253

End: 1736975

Strand: Reverse

Name: bioD [H]

Synonym: GSU1583

Alternate gene names: 39996683

Gene position: 1736975-1736253 (Counterclockwise)

Preceding gene: 39996684

Following gene: 39996682

Centisome position: 45.54

GC content: 61.96

Gene sequence:

>723_bases
ATGGCTGAGAAAGGAATTTTCATTACCGGAACTGATACCGGAGTGGGCAAAACAATCGTAGCGGCGACCATCGCCCGCCT
GCTGCGAGACCGGGGCGTAAATGTGGGCGTGATGAAGCCGGTCACCAGCGGCTGCATTGAACGCGACGGCACCCTGATTT
CCGAAGATGCCGAATTGCTCACCTGGGCCGCCGGGGTTCCCCTTGATGAAGCCTGCGCCCCCTACCGCCTTCGCACCCCG
ATCGCTCCGTCCGTGGCCGCCAGCCGCGAAGGGGTCAAGATCGATTTCAATCACCTGAAGGATGCCTATGAAACACTGCG
GCAGCGGCATGACTTCGTCATCGTCGAAGGTGCCGGAGGGCTCATGGTCCCCCTGTCGGGCGGCATGCTGGTGGCGGATC
TGATGAGCCTCCTTAAACTGTCGCTTCTCGTGGTGGCCCGTCCGAATCTGGGAACCATCAACCACACGGTTCTCACCTGT
TATGCCGCGCGCCAGCTCGGACTGGATGTGCGCGGCGTCATCGTCAACAGCTATCCCGAGTCGCCGGACATGGCCGAAGA
ATACGCGCCGCACCTGATCGACTCGCTCTCCGGCGCACCGCTGCTCGGCGTCTTTCCCCGCATCGAGGGAGCTGAAGGAC
GTGCCATGGTGGAACAGCTCGCGGCGCGCCTGGCAACCGAACCAACCACCAGGATACTGGTAAGGGAGATTGGCTGTGCC
TGA

Upstream 100 bases:

>100_bases
AGCGGCACCATGATCGGCAACTATCTTACCACCACCGGTCGTCCGCCCGAGCAGGACTGGCAGATGCTGGCCGACCTGGG
GCTTACTGTGAGGCAATGCA

Downstream 100 bases:

>100_bases
CTATGATACTCAGACCCTGAGAGACTGGGACCGTCGCCACATCTGGCACCCCTTCACCCAGATGAAGGAGTGGGAGGAAA
GCGAACCAGTGGTGATCGTT

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MAEKGIFITGTDTGVGKTIVAATIARLLRDRGVNVGVMKPVTSGCIERDGTLISEDAELLTWAAGVPLDEACAPYRLRTP
IAPSVAASREGVKIDFNHLKDAYETLRQRHDFVIVEGAGGLMVPLSGGMLVADLMSLLKLSLLVVARPNLGTINHTVLTC
YAARQLGLDVRGVIVNSYPESPDMAEEYAPHLIDSLSGAPLLGVFPRIEGAEGRAMVEQLAARLATEPTTRILVREIGCA

Sequences:

>Translated_240_residues
MAEKGIFITGTDTGVGKTIVAATIARLLRDRGVNVGVMKPVTSGCIERDGTLISEDAELLTWAAGVPLDEACAPYRLRTP
IAPSVAASREGVKIDFNHLKDAYETLRQRHDFVIVEGAGGLMVPLSGGMLVADLMSLLKLSLLVVARPNLGTINHTVLTC
YAARQLGLDVRGVIVNSYPESPDMAEEYAPHLIDSLSGAPLLGVFPRIEGAEGRAMVEQLAARLATEPTTRILVREIGCA
>Mature_239_residues
AEKGIFITGTDTGVGKTIVAATIARLLRDRGVNVGVMKPVTSGCIERDGTLISEDAELLTWAAGVPLDEACAPYRLRTPI
APSVAASREGVKIDFNHLKDAYETLRQRHDFVIVEGAGGLMVPLSGGMLVADLMSLLKLSLLVVARPNLGTINHTVLTCY
AARQLGLDVRGVIVNSYPESPDMAEEYAPHLIDSLSGAPLLGVFPRIEGAEGRAMVEQLAARLATEPTTRILVREIGCA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=206, Percent_Identity=33.0097087378641, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87081944, Length=218, Percent_Identity=32.5688073394495, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324385, Length=187, Percent_Identity=32.0855614973262, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25544; Mature: 25413

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKGIFITGTDTGVGKTIVAATIARLLRDRGVNVGVMKPVTSGCIERDGTLISEDAELL
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCEECCCHHHH
TWAAGVPLDEACAPYRLRTPIAPSVAASREGVKIDFNHLKDAYETLRQRHDFVIVEGAGG
EEECCCCHHHCCCCEEECCCCCCCHHCCCCCCEEEHHHHHHHHHHHHHHCCEEEEECCCC
LMVPLSGGMLVADLMSLLKLSLLVVARPNLGTINHTVLTCYAARQLGLDVRGVIVNSYPE
EEEEECCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
SPDMAEEYAPHLIDSLSGAPLLGVFPRIEGAEGRAMVEQLAARLATEPTTRILVREIGCA
CCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AEKGIFITGTDTGVGKTIVAATIARLLRDRGVNVGVMKPVTSGCIERDGTLISEDAELL
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCEECCCHHHH
TWAAGVPLDEACAPYRLRTPIAPSVAASREGVKIDFNHLKDAYETLRQRHDFVIVEGAGG
EEECCCCHHHCCCCEEECCCCCCCHHCCCCCCEEEHHHHHHHHHHHHHHCCEEEEECCCC
LMVPLSGGMLVADLMSLLKLSLLVVARPNLGTINHTVLTCYAARQLGLDVRGVIVNSYPE
EEEEECCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
SPDMAEEYAPHLIDSLSGAPLLGVFPRIEGAEGRAMVEQLAARLATEPTTRILVREIGCA
CCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA