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The map label for this gene is infC

Identifier: 39996616

GI number: 39996616

Start: 1664075

End: 1664593

Strand: Direct

Name: infC

Synonym: GSU1516

Alternate gene names: 39996616

Gene position: 1664075-1664593 (Clockwise)

Preceding gene: 39996615

Following gene: 39996617

Centisome position: 43.63

GC content: 54.72

Gene sequence:

>519_bases
ATAGCGAAGCCTACGGTAAATATCAATCAGGCCATACGGGCGCGCGAGGTGCGCGTTGTCGGCGCAGACAGCGAACAGCT
GGGGATCATGTCTCTCCAGGAGGCTCTTGCGCTGGCTGAAGCACGGCAACTCGACCTGGTGGAGGTTTCACCCACAGCGG
TGCCGCCGGTTTGCCGGATCATGGATTACGGCAAGTTCAAGTACCAGCAAAGCAAAAAACTTCAGGAAGCACGGAAAAAG
CAGTCCCACGTGCAGGTCAAGGAAGTAAAGCTCAGGCCCAAGACCGATGAGCATGACCTGATGACCAAGATCAAGCATGT
GAGGCGCTTTATCGAGGAGGGAAACAAGGCGAAGGTAACCCTTGTGTTCCGGGGGCGTGAGATAACGCACCTGGAATTCG
GTTCCCGGGCCCTCGACCGTGTTGCCGCCGAATTGGAAGATATCGCAGTTGTCGAATTCAAACCGAAGATGGAAGGGCGT
AGCATGTTCATGATCGTTGCGCCCAAAGTCAAAAAATAG

Upstream 100 bases:

>100_bases
CCCGGTTCCGCGACGGGTCAAACCTCGCGGCCATGAAGCCGGAGGAGTTTGTTGCGTTTGTAAACGACGAAGTGAAACGC
TTCAATTAGGAGGTGGTGCC

Downstream 100 bases:

>100_bases
AGAAGCTACCGAGAACGCAGCAAAGGAGAATAGAGCAATGCCCAAGATCAAGACCAATCGCGGTGCCGCAAAGCGCTTCA
AGAAGACCGGTACCGGCAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAKPTVNINQAIRAREVRVVGADSEQLGIMSLQEALALAEARQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEARKK
QSHVQVKEVKLRPKTDEHDLMTKIKHVRRFIEEGNKAKVTLVFRGREITHLEFGSRALDRVAAELEDIAVVEFKPKMEGR
SMFMIVAPKVKK

Sequences:

>Translated_172_residues
MAKPTVNINQAIRAREVRVVGADSEQLGIMSLQEALALAEARQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEARKK
QSHVQVKEVKLRPKTDEHDLMTKIKHVRRFIEEGNKAKVTLVFRGREITHLEFGSRALDRVAAELEDIAVVEFKPKMEGR
SMFMIVAPKVKK
>Mature_171_residues
AKPTVNINQAIRAREVRVVGADSEQLGIMSLQEALALAEARQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEARKKQ
SHVQVKEVKLRPKTDEHDLMTKIKHVRRFIEEGNKAKVTLVFRGREITHLEFGSRALDRVAAELEDIAVVEFKPKMEGRS
MFMIVAPKVKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=56.3953488372093, Blast_Score=177, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_GEOSL (Q74D03)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952567.1
- HSSP:   P03000
- ProteinModelPortal:   Q74D03
- SMR:   Q74D03
- GeneID:   2687717
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1516
- NMPDR:   fig|243231.1.peg.1505
- TIGR:   GSU1516
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   GSUL243231:GSU_1516-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 19592; Mature: 19461

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPTVNINQAIRAREVRVVGADSEQLGIMSLQEALALAEARQLDLVEVSPTAVPPVCRI
CCCCCCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHH
MDYGKFKYQQSKKLQEARKKQSHVQVKEVKLRPKTDEHDLMTKIKHVRRFIEEGNKAKVT
HHCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEE
LVFRGREITHLEFGSRALDRVAAELEDIAVVEFKPKMEGRSMFMIVAPKVKK
EEECCCEEEEEECCHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
AKPTVNINQAIRAREVRVVGADSEQLGIMSLQEALALAEARQLDLVEVSPTAVPPVCRI
CCCCCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHH
MDYGKFKYQQSKKLQEARKKQSHVQVKEVKLRPKTDEHDLMTKIKHVRRFIEEGNKAKVT
HHCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEE
LVFRGREITHLEFGSRALDRVAAELEDIAVVEFKPKMEGRSMFMIVAPKVKK
EEECCCEEEEEECCHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA