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The map label for this gene is tolC [H]

Identifier: 39996582

GI number: 39996582

Start: 1622483

End: 1623763

Strand: Reverse

Name: tolC [H]

Synonym: GSU1482

Alternate gene names: 39996582

Gene position: 1623763-1622483 (Counterclockwise)

Preceding gene: 39996583

Following gene: 39996581

Centisome position: 42.57

GC content: 61.9

Gene sequence:

>1281_bases
ATGAAACCACTACCAATCCGTAGCATCCCCTTCCTGATCCTTGCGCTCTGTGCAGCGACGCCGGCCATGGCCAGCGCGCT
TTCACTCAAAGAATGCCTGAGTCTGGCCGCGGCCGGCAACTACTCGCTGGCCGTAACAGCTTCCGACCGCCTTATCGCGC
AAGAGGCGATCACCCAGGCCCGAAGCGGCTTTCTCCCGCGCGTGGACTTCCAGGGCGGGTACACCCTCCAGGCAAAGCCC
CAGGCGGTGAATTTCGGCGAACGGGGCAGCATTGAGACCCAGGACGGCACCTATGGATTCTTCAACCTCTCCGTGACCCA
GACCATCTATGATTTCGGCCGCACCTCCTCGCGCCGGCAGCGGGCGTCCCTCCTCCACGAGGCGACTGCCCAGCAATACG
CAGCGGCCGAGAAAGACGTATTCCTCCAGGTTGTCGAGGCCTATTTCGGCATCCTCGAAGCACGGCGCCTCCTCGGCACC
GCCGAGGAGGAAGTGGCCCAGCGAACCGACCATCTGCGGATCGCCACCAATCTCTTCGAACAGGGGGTGGTCACCCGCAA
CGACCTGCTCCAGGCCCAGGTCAGACTGGCGGAAAGCTCCCAGAAGCGCCTGGTGGCGGCAAATCGTCTCGAAAACCGCT
GGATGTACCTGAATCACCTGACCGGAAGACCTCTCGATCAGCGTGACGAGCTTGAAGAGGGAACTGAATCCGCCATGCCC
GATACCGCCGGGGCCGAAGAACGCGCCTTTGCCAATCGTCCCGAACTGACTGCCCTTGCGCGAAGCGCAGACGCCGCCGA
TGCAGAAGTTTCCGAGGCCAGGAGCGGTTACTACCCCGAACTCTATGCCAAGGCCGGTGTCGACTACGTGGAGAACAGCA
AGGTGCGCGAGCAGGCAATCTATGCCGCAACGGTGGGGCTGAAGATCAATCTCTTCGAAGGCTTCGCCACGGAATCCAGG
CACCGGCAGTCAGTCGAGCGCCTCACCAGGAGCCGCGATGCGTTGCGACTGGCGCGGGAACAGGTCCGGCTCGAGCTTGC
CACTGCCCTGAACGATGCCCGGGTGGCGGAACAGCGGATCAAGAGCGTCGAAACGGCAATCCGCCAGGGAGAAGAAAACC
TGAGGATCAATAGGGACCGCTACCAGGCTCAGGTCGGCACGGCCACTGATGTGCTCGATGCCCAGACACTGCTTACCCAG
ATAAAGACCGATTATCACCGGGCCGTTTTCGACTTCCAGGTCGCAAAGGCCCGTGTCAGCAAAGCCATGGGAGAACTGTA
G

Upstream 100 bases:

>100_bases
GCGGAGGTGCTTGCCCGCTTTCTCGCTCCCCTATCAGAAGACGAACAGAACAGTCTGCATCATCTCCTGGAAAAAATCAG
GACCGCCCCGGAGAATCGCC

Downstream 100 bases:

>100_bases
GAATGACAACGGAACAGGAACTACCGGACCGGGGAGAAAACCGGGAAGCCCCTTCGGCCCAGACGGCGCCACAGGGCAAG
GGGAGCGGCGGCAAACGGAG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKPLPIRSIPFLILALCAATPAMASALSLKECLSLAAAGNYSLAVTASDRLIAQEAITQARSGFLPRVDFQGGYTLQAKP
QAVNFGERGSIETQDGTYGFFNLSVTQTIYDFGRTSSRRQRASLLHEATAQQYAAAEKDVFLQVVEAYFGILEARRLLGT
AEEEVAQRTDHLRIATNLFEQGVVTRNDLLQAQVRLAESSQKRLVAANRLENRWMYLNHLTGRPLDQRDELEEGTESAMP
DTAGAEERAFANRPELTALARSADAADAEVSEARSGYYPELYAKAGVDYVENSKVREQAIYAATVGLKINLFEGFATESR
HRQSVERLTRSRDALRLAREQVRLELATALNDARVAEQRIKSVETAIRQGEENLRINRDRYQAQVGTATDVLDAQTLLTQ
IKTDYHRAVFDFQVAKARVSKAMGEL

Sequences:

>Translated_426_residues
MKPLPIRSIPFLILALCAATPAMASALSLKECLSLAAAGNYSLAVTASDRLIAQEAITQARSGFLPRVDFQGGYTLQAKP
QAVNFGERGSIETQDGTYGFFNLSVTQTIYDFGRTSSRRQRASLLHEATAQQYAAAEKDVFLQVVEAYFGILEARRLLGT
AEEEVAQRTDHLRIATNLFEQGVVTRNDLLQAQVRLAESSQKRLVAANRLENRWMYLNHLTGRPLDQRDELEEGTESAMP
DTAGAEERAFANRPELTALARSADAADAEVSEARSGYYPELYAKAGVDYVENSKVREQAIYAATVGLKINLFEGFATESR
HRQSVERLTRSRDALRLAREQVRLELATALNDARVAEQRIKSVETAIRQGEENLRINRDRYQAQVGTATDVLDAQTLLTQ
IKTDYHRAVFDFQVAKARVSKAMGEL
>Mature_426_residues
MKPLPIRSIPFLILALCAATPAMASALSLKECLSLAAAGNYSLAVTASDRLIAQEAITQARSGFLPRVDFQGGYTLQAKP
QAVNFGERGSIETQDGTYGFFNLSVTQTIYDFGRTSSRRQRASLLHEATAQQYAAAEKDVFLQVVEAYFGILEARRLLGT
AEEEVAQRTDHLRIATNLFEQGVVTRNDLLQAQVRLAESSQKRLVAANRLENRWMYLNHLTGRPLDQRDELEEGTESAMP
DTAGAEERAFANRPELTALARSADAADAEVSEARSGYYPELYAKAGVDYVENSKVREQAIYAATVGLKINLFEGFATESR
HRQSVERLTRSRDALRLAREQVRLELATALNDARVAEQRIKSVETAIRQGEENLRINRDRYQAQVGTATDVLDAQTLLTQ
IKTDYHRAVFDFQVAKARVSKAMGEL

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=438, Percent_Identity=23.2876712328767, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47299; Mature: 47299

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLPIRSIPFLILALCAATPAMASALSLKECLSLAAAGNYSLAVTASDRLIAQEAITQA
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
RSGFLPRVDFQGGYTLQAKPQAVNFGERGSIETQDGTYGFFNLSVTQTIYDFGRTSSRRQ
HHCCCCCEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCHHHH
RASLLHEATAQQYAAAEKDVFLQVVEAYFGILEARRLLGTAEEEVAQRTDHLRIATNLFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QGVVTRNDLLQAQVRLAESSQKRLVAANRLENRWMYLNHLTGRPLDQRDELEEGTESAMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCC
DTAGAEERAFANRPELTALARSADAADAEVSEARSGYYPELYAKAGVDYVENSKVREQAI
CCCCCHHHHHCCCCCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHCCCCHHHCCHHHHHHH
YAATVGLKINLFEGFATESRHRQSVERLTRSRDALRLAREQVRLELATALNDARVAEQRI
HHEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSVETAIRQGEENLRINRDRYQAQVGTATDVLDAQTLLTQIKTDYHRAVFDFQVAKARVS
HHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAMGEL
HHHCCC
>Mature Secondary Structure
MKPLPIRSIPFLILALCAATPAMASALSLKECLSLAAAGNYSLAVTASDRLIAQEAITQA
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
RSGFLPRVDFQGGYTLQAKPQAVNFGERGSIETQDGTYGFFNLSVTQTIYDFGRTSSRRQ
HHCCCCCEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCHHHH
RASLLHEATAQQYAAAEKDVFLQVVEAYFGILEARRLLGTAEEEVAQRTDHLRIATNLFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QGVVTRNDLLQAQVRLAESSQKRLVAANRLENRWMYLNHLTGRPLDQRDELEEGTESAMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCC
DTAGAEERAFANRPELTALARSADAADAEVSEARSGYYPELYAKAGVDYVENSKVREQAI
CCCCCHHHHHCCCCCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHCCCCHHHCCHHHHHHH
YAATVGLKINLFEGFATESRHRQSVERLTRSRDALRLAREQVRLELATALNDARVAEQRI
HHEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSVETAIRQGEENLRINRDRYQAQVGTATDVLDAQTLLTQIKTDYHRAVFDFQVAKARVS
HHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAMGEL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]