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The map label for this gene is tsr [C]

Identifier: 39996400

GI number: 39996400

Start: 1418548

End: 1420254

Strand: Direct

Name: tsr [C]

Synonym: GSU1298

Alternate gene names: 39996400

Gene position: 1418548-1420254 (Clockwise)

Preceding gene: 39996399

Following gene: 39996401

Centisome position: 37.19

GC content: 57.35

Gene sequence:

>1707_bases
ATGACGTGGTTCCACAATTTAAAAATTGCATCTAAGCTGATAGTTGGTTTTGCTCTTGTTACCCTGATAGCTTGTGTTAT
AGGAGCTATTGGGATAACAAAAATAATGCAGATAGAAAAAGCCGATACAGAGATGTATGAGCTAAATGCAAAGCCAATGG
GACCTATCCTGACTACAGCTGTGGCTTTTCAGAGGATCAGGGTCAACTATCGTGAGATAGCACTGGAACAGACTAATGAA
GGCAAGGTAAAGTTTTCCAACAGAATTAAAGAGTTGCAAAAGACAATAGATGACAATTTGCCCGAAATAGAAAAGTCTCT
GAAGTCGGAAGAGACTAAGAAAGCCTACGCAGATATAAAGGCAGAGTTGGCTAAGTTTGCCCCTCATCTTGACAAGATTG
TGGCCCTGGCCATGGATGGGAAGAATGACCAGGCAGTGGCCTATATGAGGAGTGACTCCGTGGCCGGGATCGCCCGGTCC
GTGGACGACTCGATTCAGAAACTCGCTGACCTGAAAATTGATCTGGCCAAGAAGAAATCCGACGCCAATACCGCCGCCGC
CAAGGCTGCGGTGGCGATGACGGGCATCATCCTCGTGCTCGGTGTTGCCCTGGCGGTCGGACTCGGCATATTCCTTTCCC
GCATCATCAGCCGCCCGCTCAGATCGGCCGTGGACGTTTCGAACCGCCTGTCGGAAGGAGACCTGACCGTAACGATCGAA
GCGACGAGCAAGGACGAGACGGGTCAGCTGCTTGCGGCGATGCACAACATGGTAGAGAAGCTGAAGGGCGTGGTAGCTGA
CGTGAAGAGCGCGGCAGACAACGTTGCCGCTGGCAGCCAGGAGCTCTCCTCCAGCTCCGAGGAGATGAGCCAGGGAGCCA
CCGAGCAGGCGGCCGCGGCCGAAGAGGCCTCCAGCTCCATGGAGCAGATGAGCTCCAACATCCGGCAGAACGCTGACAAC
GCCACCCAGACCGAGAAGATCGCCCTGAAGAGCGCCGCCGATGCCAAGCAGGGCGGCACGGCCGTGGCAGAAACCGTCGT
GGCCATGAAGGAAATCGCCTCCAAGATCTCGATCATCGAAGAGATAGCCCGCCAGACGAACCTGCTGGCGTTGAACGCAG
CCATCGAAGCGGCGCGTGCCGGTGAGCACGGCAAAGGGTTCGCGGTGGTAGCGGCCGAGGTCAGAAAGCTTGCCGAGCGG
AGCCAGAAGGCGGCGGGCGAGATCAGCGAGCTGTCTGCCTCCAGCGTTCAGGTAGCGGAAGAAGCCGGCGAGATGCTGAC
GCGGATCGTGCCGGACATCCAGCGTACCGCGGAATTGGTGCAGGAGATCAGCGCCGCGTGCAAGGAGCAGGACACGGGAG
CGGAGCAGATCAACAAAGCTATCCAGCAGCTTGACCAGGTGATCCAGCAGAACGCCAGCGCCAGCGAAGAGATGGCGTCC
ACCAGCGAAGAGCTGGCCAGCCAGGCCGAACAGCTGCAGGAAACAATCGCCTTCTTCAAAACCGGCGAACAGGTGGGTTT
GGTGCGCAAAGCGGCAGCAGTGCGCCAGTTCGCGGCCAAGAAAAAGGCAGCGATCCCTCATCTGGGTCACGGCACGTCCA
ACGGCTACCACGCCGAACCCGCGACGTCGCGGAAAGTGGCGGTGGGCGGCGGGGTAGACCTGAACCTGGACAGCGATCAC
CTTGACGACCAGTTCGAGAAATTCTAG

Upstream 100 bases:

>100_bases
GGGATTTCCCTATATTCCTGTAAACGGTTTTCCCGATAGGTATACACAGAGCAGGCAAAGTTCATGTGCTGATAAGTTAC
GCCAAGCAAAGGAGGATAAT

Downstream 100 bases:

>100_bases
GAGGGAGCGATGGCACACGCAGACACAACGGAAACGCGGCAGTACCTGACCTTCACTCTTGCCGGGGAAGTCTTTGGGGT
GGACGTGGCCAAGGTCCGTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTWFHNLKIASKLIVGFALVTLIACVIGAIGITKIMQIEKADTEMYELNAKPMGPILTTAVAFQRIRVNYREIALEQTNE
GKVKFSNRIKELQKTIDDNLPEIEKSLKSEETKKAYADIKAELAKFAPHLDKIVALAMDGKNDQAVAYMRSDSVAGIARS
VDDSIQKLADLKIDLAKKKSDANTAAAKAAVAMTGIILVLGVALAVGLGIFLSRIISRPLRSAVDVSNRLSEGDLTVTIE
ATSKDETGQLLAAMHNMVEKLKGVVADVKSAADNVAAGSQELSSSSEEMSQGATEQAAAAEEASSSMEQMSSNIRQNADN
ATQTEKIALKSAADAKQGGTAVAETVVAMKEIASKISIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAER
SQKAAGEISELSASSVQVAEEAGEMLTRIVPDIQRTAELVQEISAACKEQDTGAEQINKAIQQLDQVIQQNASASEEMAS
TSEELASQAEQLQETIAFFKTGEQVGLVRKAAAVRQFAAKKKAAIPHLGHGTSNGYHAEPATSRKVAVGGGVDLNLDSDH
LDDQFEKF

Sequences:

>Translated_568_residues
MTWFHNLKIASKLIVGFALVTLIACVIGAIGITKIMQIEKADTEMYELNAKPMGPILTTAVAFQRIRVNYREIALEQTNE
GKVKFSNRIKELQKTIDDNLPEIEKSLKSEETKKAYADIKAELAKFAPHLDKIVALAMDGKNDQAVAYMRSDSVAGIARS
VDDSIQKLADLKIDLAKKKSDANTAAAKAAVAMTGIILVLGVALAVGLGIFLSRIISRPLRSAVDVSNRLSEGDLTVTIE
ATSKDETGQLLAAMHNMVEKLKGVVADVKSAADNVAAGSQELSSSSEEMSQGATEQAAAAEEASSSMEQMSSNIRQNADN
ATQTEKIALKSAADAKQGGTAVAETVVAMKEIASKISIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAER
SQKAAGEISELSASSVQVAEEAGEMLTRIVPDIQRTAELVQEISAACKEQDTGAEQINKAIQQLDQVIQQNASASEEMAS
TSEELASQAEQLQETIAFFKTGEQVGLVRKAAAVRQFAAKKKAAIPHLGHGTSNGYHAEPATSRKVAVGGGVDLNLDSDH
LDDQFEKF
>Mature_567_residues
TWFHNLKIASKLIVGFALVTLIACVIGAIGITKIMQIEKADTEMYELNAKPMGPILTTAVAFQRIRVNYREIALEQTNEG
KVKFSNRIKELQKTIDDNLPEIEKSLKSEETKKAYADIKAELAKFAPHLDKIVALAMDGKNDQAVAYMRSDSVAGIARSV
DDSIQKLADLKIDLAKKKSDANTAAAKAAVAMTGIILVLGVALAVGLGIFLSRIISRPLRSAVDVSNRLSEGDLTVTIEA
TSKDETGQLLAAMHNMVEKLKGVVADVKSAADNVAAGSQELSSSSEEMSQGATEQAAAAEEASSSMEQMSSNIRQNADNA
TQTEKIALKSAADAKQGGTAVAETVVAMKEIASKISIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERS
QKAAGEISELSASSVQVAEEAGEMLTRIVPDIQRTAELVQEISAACKEQDTGAEQINKAIQQLDQVIQQNASASEEMAST
SEELASQAEQLQETIAFFKTGEQVGLVRKAAAVRQFAAKKKAAIPHLGHGTSNGYHAEPATSRKVAVGGGVDLNLDSDHL
DDQFEKF

Specific function: May bind attractants or detect changes in the extracellular concentration of soluble sugars [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=410, Percent_Identity=35.8536585365854, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1787690, Length=524, Percent_Identity=30.3435114503817, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1788194, Length=328, Percent_Identity=36.5853658536585, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1788195, Length=331, Percent_Identity=36.5558912386707, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1789453, Length=325, Percent_Identity=32.3076923076923, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60456; Mature: 60325

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWFHNLKIASKLIVGFALVTLIACVIGAIGITKIMQIEKADTEMYELNAKPMGPILTTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHH
VAFQRIRVNYREIALEQTNEGKVKFSNRIKELQKTIDDNLPEIEKSLKSEETKKAYADIK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AELAKFAPHLDKIVALAMDGKNDQAVAYMRSDSVAGIARSVDDSIQKLADLKIDLAKKKS
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DANTAAAKAAVAMTGIILVLGVALAVGLGIFLSRIISRPLRSAVDVSNRLSEGDLTVTIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
ATSKDETGQLLAAMHNMVEKLKGVVADVKSAADNVAAGSQELSSSSEEMSQGATEQAAAA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCHHHHHHH
EEASSSMEQMSSNIRQNADNATQTEKIALKSAADAKQGGTAVAETVVAMKEIASKISIIE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERSQKAAGEISELSASSVQVAE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGEMLTRIVPDIQRTAELVQEISAACKEQDTGAEQINKAIQQLDQVIQQNASASEEMAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TSEELASQAEQLQETIAFFKTGEQVGLVRKAAAVRQFAAKKKAAIPHLGHGTSNGYHAEP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ATSRKVAVGGGVDLNLDSDHLDDQFEKF
CCCCEEEECCCEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
TWFHNLKIASKLIVGFALVTLIACVIGAIGITKIMQIEKADTEMYELNAKPMGPILTTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHH
VAFQRIRVNYREIALEQTNEGKVKFSNRIKELQKTIDDNLPEIEKSLKSEETKKAYADIK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AELAKFAPHLDKIVALAMDGKNDQAVAYMRSDSVAGIARSVDDSIQKLADLKIDLAKKKS
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DANTAAAKAAVAMTGIILVLGVALAVGLGIFLSRIISRPLRSAVDVSNRLSEGDLTVTIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
ATSKDETGQLLAAMHNMVEKLKGVVADVKSAADNVAAGSQELSSSSEEMSQGATEQAAAA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCHHHHHHH
EEASSSMEQMSSNIRQNADNATQTEKIALKSAADAKQGGTAVAETVVAMKEIASKISIIE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERSQKAAGEISELSASSVQVAE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGEMLTRIVPDIQRTAELVQEISAACKEQDTGAEQINKAIQQLDQVIQQNASASEEMAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TSEELASQAEQLQETIAFFKTGEQVGLVRKAAAVRQFAAKKKAAIPHLGHGTSNGYHAEP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ATSRKVAVGGGVDLNLDSDHLDDQFEKF
CCCCEEEECCCEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8436949 [H]