Click here to switch to the map view.

The map label for this gene is ygfA [C]

Identifier: 39996238

GI number: 39996238

Start: 1219665

End: 1220228

Strand: Direct

Name: ygfA [C]

Synonym: GSU1136

Alternate gene names: 39996238

Gene position: 1219665-1220228 (Clockwise)

Preceding gene: 39996237

Following gene: 39996239

Centisome position: 31.98

GC content: 60.11

Gene sequence:

>564_bases
ATGCCCAAGCGCGTTCTGAGACAGTCAATGCTTGCGCTGCGGAAGTCCCTGGCCCCTGTCGAGGCCCGGTGGGCATCCGA
GGCCATTCAGCGCTCGTTTGTGGAAAGCGAGGGCTTCCGGAATGCCCGGGTCATTGCTCTCTACGCCCCCATCAGGGGGG
AGGTCGATACGAGTGACGTGCTGCGGCTTGCCCTCGACCAAGGAAAGACGGTTCTTCTGCCTGCCGTGTGCGGCGACGAG
CTCCGTTTCATCGAAGTGACTGACCCGGCAGGACTCCGCTCAGGCTCATTCGGTATTCCTGAGCCCTGTCTGACGGGAAA
GGCCGTTGCTCCCGACTGCGCGGACATCATTGTTGTGCCGGGGGTGGCCTTTGACTTGGCAGGCCACCGGATCGGCTATG
GGAAGGGGTTCTACGACCGGGCACTCCATCATTTGGAGGGAACAGGCCGGCTTGTCGGTTTTTGTTACGATTTCCAGCTC
GTCGATGAAATACGGGGAGAGCCTCACGATGTGGCACTCGACCTGATCGTTACCGAGAAGAGGATCATTCATCCTCTCGG
TTAG

Upstream 100 bases:

>100_bases
CATATCTTCTCCAATTACCCTCCAGGAATCCTCCCCTCCTCGGACCCGTCCCCGTGTACCGTTATTGACCGATGACTCTG
TGTCACGGTCACGCGATTCA

Downstream 100 bases:

>100_bases
AAATATACCTGAGGAGGTACCGGAACATTGAAGATAGAACTGGCAATTATTTTCATCGTCCTCGCGGCAGGAGCGGGATT
TCTGATTGGAAACCTGCTGC

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPKRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDVLRLALDQGKTVLLPAVCGDE
LRFIEVTDPAGLRSGSFGIPEPCLTGKAVAPDCADIIVVPGVAFDLAGHRIGYGKGFYDRALHHLEGTGRLVGFCYDFQL
VDEIRGEPHDVALDLIVTEKRIIHPLG

Sequences:

>Translated_187_residues
MPKRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDVLRLALDQGKTVLLPAVCGDE
LRFIEVTDPAGLRSGSFGIPEPCLTGKAVAPDCADIIVVPGVAFDLAGHRIGYGKGFYDRALHHLEGTGRLVGFCYDFQL
VDEIRGEPHDVALDLIVTEKRIIHPLG
>Mature_186_residues
PKRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDVLRLALDQGKTVLLPAVCGDEL
RFIEVTDPAGLRSGSFGIPEPCLTGKAVAPDCADIIVVPGVAFDLAGHRIGYGKGFYDRALHHLEGTGRLVGFCYDFQLV
DEIRGEPHDVALDLIVTEKRIIHPLG

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=174, Percent_Identity=28.735632183908, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17510857, Length=194, Percent_Identity=30.9278350515464, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI161077430, Length=171, Percent_Identity=28.6549707602339, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 20433; Mature: 20302

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHH
LRLALDQGKTVLLPAVCGDELRFIEVTDPAGLRSGSFGIPEPCLTGKAVAPDCADIIVVP
HHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
GVAFDLAGHRIGYGKGFYDRALHHLEGTGRLVGFCYDFQLVDEIRGEPHDVALDLIVTEK
CEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEHHHHCCCCCCEEEEEEEECH
RIIHPLG
HHCCCCC
>Mature Secondary Structure 
PKRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHH
LRLALDQGKTVLLPAVCGDELRFIEVTDPAGLRSGSFGIPEPCLTGKAVAPDCADIIVVP
HHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
GVAFDLAGHRIGYGKGFYDRALHHLEGTGRLVGFCYDFQLVDEIRGEPHDVALDLIVTEK
CEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEHHHHCCCCCCEEEEEEEECH
RIIHPLG
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]