Click here to switch to the map view.

The map label for this gene is 39996239

Identifier: 39996239

GI number: 39996239

Start: 1220256

End: 1221818

Strand: Direct

Name: 39996239

Synonym: GSU1137

Alternate gene names: NA

Gene position: 1220256-1221818 (Clockwise)

Preceding gene: 39996238

Following gene: 39996240

Centisome position: 31.99

GC content: 56.24

Gene sequence:

>1563_bases
TTGAAGATAGAACTGGCAATTATTTTCATCGTCCTCGCGGCAGGAGCGGGATTTCTGATTGGAAACCTGCTGCGCAAGAA
ACTCTCTGATTCTCTGGTAAGCAAGGCCGAAGAACTCGCCTCCCGCATCGTAGAGGATGCCAAGCGCGAAGCTGAAACGA
TCAGCAAGGAAGCCGCCCTTCAGGCCAAGGATGTCGTCTATCAGGCAAAAGCCGATTTCGAGCGGGAAGCAAAGGAAAAG
CACAAGGATCTTCAGACTCTGGAAAAGCGCCTTCAGCAGAAGGAAGAGAACCTCGATAAAAAGATGAACCTTTTCGATCA
GCGCGATGCCGACCTGACGAAGAAGGAGCAGGGTATCCTTGCGCGGGAGCAGTCTCTCAACCGGAAAGAGGAATCCCTTG
ATGCGCTCGTGGCCGAGCAACGGGCGAAGCTTGAACAGATTTCCGGCATGAGCTCGGCCGAAGCCAAGAAGATCCTCATG
GACGCCATGGAGAGCGAGGCGAAACTTGATGCAGCCAAGCGGATCAAGGCCATCGAAGAGGAGGCCCGCGAGACTGCGGA
CAAGAAATCCAAGGAAATCATTTCTCTTGCCGTTCAGCGGTATGCGGGCGAGTACGTTGCCGAAAAGACCGTATCGGTGG
TAGCCCTCCCCTCCGACGAAATGAAGGGGCGAATCATCGGTCGTGAAGGCCGCAATATCCGGGCCCTTGAGGCGGCCACC
GGCATCGACCTCATCATCGACGATACCCCCGAGGCGGTTATTCTTTCAGGCTTCAATCCGGTTCGCCGAGAAGTGGCAAA
GATCGCCCTTGAGAAACTCATCACTGACGGGCGGATTCACCCCGGCCGCATCGAAGAAGTGGTGGCCAAGGCAGAGGAGG
AAGTGGAACAAGCCGTCAAGGAAGCTGGTGATCAGGCGGCCTTTGACCTCGGAGTACACGGCATCCATCCTGAAATCCTC
AAGCTCATCGGCCGGTTGAAATACCGCACGTCTTACAGCCAGAATGTTTACCAGCATTCTCTTGAGGTCGCCTTCCTCTG
CGGCATCATGGCCTCGGAGTTGGGCATCAACGTCAAGCAGGCAAAGCGCGCCGGTCTGCTCCATGACCTGGGCAAGGCGG
TGGACCATGAGGTTGAAGGATCCCACGCGGTCATCGGCGCTGAACTTGCGCGTAAATATGGTGAGTCACCCAAAATTGTC
CACGCCATCATGGCTCACCACGAGGATGAAAAGCCGAATTCGATCCTCGCCGTCCTCGTTCAGGCCGCTGACGCCCTCTC
AGGCGCACGGCCGGGGGCGCGCCGGGAAATGATGGAAACATACGTGAAGCGGCTTGAGGACCTTGAACGGATATCCTGTT
CCTTTGGCGGTGTGAACAACTCCTTTGCCATTCAGGCCGGCAGAGAAATCCGCGTCATGGTATCGAGCGAAGAGGTCTCT
GACGAGCGGGCTGTTCTGCTGGCCAAGGACATCGCCAAGAAGATCGAGGCCGAGATGACCTATCCCGGTCAGATCAAGGT
GAATGTTATCCGGGAAACCCGCGCCATAGAGTATGCCCGTTAA

Upstream 100 bases:

>100_bases
ACGGGGAGAGCCTCACGATGTGGCACTCGACCTGATCGTTACCGAGAAGAGGATCATTCATCCTCTCGGTTAGAAATATA
CCTGAGGAGGTACCGGAACA

Downstream 100 bases:

>100_bases
TATCCTCTTTATTGGCGATATTGTCGGGAGCCCGGGGCGACAGGCGCTTGTCCGTGAACTTCACCGGCTCGTGGATCATC
ACCGGGTGGATCTTGTTGTA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKIELAIIFIVLAAGAGFLIGNLLRKKLSDSLVSKAEELASRIVEDAKREAETISKEAALQAKDVVYQAKADFEREAKEK
HKDLQTLEKRLQQKEENLDKKMNLFDQRDADLTKKEQGILAREQSLNRKEESLDALVAEQRAKLEQISGMSSAEAKKILM
DAMESEAKLDAAKRIKAIEEEARETADKKSKEIISLAVQRYAGEYVAEKTVSVVALPSDEMKGRIIGREGRNIRALEAAT
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQAVKEAGDQAAFDLGVHGIHPEIL
KLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIV
HAIMAHHEDEKPNSILAVLVQAADALSGARPGARREMMETYVKRLEDLERISCSFGGVNNSFAIQAGREIRVMVSSEEVS
DERAVLLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR

Sequences:

>Translated_520_residues
MKIELAIIFIVLAAGAGFLIGNLLRKKLSDSLVSKAEELASRIVEDAKREAETISKEAALQAKDVVYQAKADFEREAKEK
HKDLQTLEKRLQQKEENLDKKMNLFDQRDADLTKKEQGILAREQSLNRKEESLDALVAEQRAKLEQISGMSSAEAKKILM
DAMESEAKLDAAKRIKAIEEEARETADKKSKEIISLAVQRYAGEYVAEKTVSVVALPSDEMKGRIIGREGRNIRALEAAT
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQAVKEAGDQAAFDLGVHGIHPEIL
KLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIV
HAIMAHHEDEKPNSILAVLVQAADALSGARPGARREMMETYVKRLEDLERISCSFGGVNNSFAIQAGREIRVMVSSEEVS
DERAVLLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
>Mature_520_residues
MKIELAIIFIVLAAGAGFLIGNLLRKKLSDSLVSKAEELASRIVEDAKREAETISKEAALQAKDVVYQAKADFEREAKEK
HKDLQTLEKRLQQKEENLDKKMNLFDQRDADLTKKEQGILAREQSLNRKEESLDALVAEQRAKLEQISGMSSAEAKKILM
DAMESEAKLDAAKRIKAIEEEARETADKKSKEIISLAVQRYAGEYVAEKTVSVVALPSDEMKGRIIGREGRNIRALEAAT
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQAVKEAGDQAAFDLGVHGIHPEIL
KLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIV
HAIMAHHEDEKPNSILAVLVQAADALSGARPGARREMMETYVKRLEDLERISCSFGGVNNSFAIQAGREIRVMVSSEEVS
DERAVLLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_GEOSL (Q74E27)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952190.1
- ProteinModelPortal:   Q74E27
- SMR:   Q74E27
- GeneID:   2685899
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1137
- NMPDR:   fig|243231.1.peg.1128
- TIGR:   GSU1137
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   GSUL243231:GSU_1137-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 57557; Mature: 57557

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc406a24)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIELAIIFIVLAAGAGFLIGNLLRKKLSDSLVSKAEELASRIVEDAKREAETISKEAAL
CEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKDVVYQAKADFEREAKEKHKDLQTLEKRLQQKEENLDKKMNLFDQRDADLTKKEQGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AREQSLNRKEESLDALVAEQRAKLEQISGMSSAEAKKILMDAMESEAKLDAAKRIKAIEE
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARETADKKSKEIISLAVQRYAGEYVAEKTVSVVALPSDEMKGRIIGREGRNIRALEAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEECCCCCCEEEEHHCC
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQAVK
CCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EAGDQAAFDLGVHGIHPEILKLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQ
HCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIVHAIMAHHEDEKPNSILAVLV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
QAADALSGARPGARREMMETYVKRLEDLERISCSFGGVNNSFAIQAGREIRVMVSSEEVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCCCC
DERAVLLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCH
>Mature Secondary Structure
MKIELAIIFIVLAAGAGFLIGNLLRKKLSDSLVSKAEELASRIVEDAKREAETISKEAAL
CEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKDVVYQAKADFEREAKEKHKDLQTLEKRLQQKEENLDKKMNLFDQRDADLTKKEQGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AREQSLNRKEESLDALVAEQRAKLEQISGMSSAEAKKILMDAMESEAKLDAAKRIKAIEE
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARETADKKSKEIISLAVQRYAGEYVAEKTVSVVALPSDEMKGRIIGREGRNIRALEAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEECCCCCCEEEEHHCC
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQAVK
CCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EAGDQAAFDLGVHGIHPEILKLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQ
HCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIVHAIMAHHEDEKPNSILAVLV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
QAADALSGARPGARREMMETYVKRLEDLERISCSFGGVNNSFAIQAGREIRVMVSSEEVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCCCC
DERAVLLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA