Click here to switch to the map view.

The map label for this gene is pepQ-1 [H]

Identifier: 39996207

GI number: 39996207

Start: 1190621

End: 1191814

Strand: Direct

Name: pepQ-1 [H]

Synonym: GSU1105

Alternate gene names: 39996207

Gene position: 1190621-1191814 (Clockwise)

Preceding gene: 39996206

Following gene: 39996208

Centisome position: 31.22

GC content: 57.96

Gene sequence:

>1194_bases
ATGCGCATCACACCAAGGGAAGAGTTGGACTACCGCATCTCCCGGCTTCAGACATACATGGCCGGGGCAGGGCTCGATGC
GGTCATCATCGTTCAGAATGCCGACTTGTTTTATTTCACCGGCACCATCCAGAGCGGCAACCTCTATGTGCCCGTTGAGG
GCGACCCCATCTACATGGTCCGCAAAGAGCATTCCCGGGCGCGGATGGAGTCGGGGCTCAAGTTGGTCGTACCGTTTTCC
TCCATGAAGAACATCCCCGGTATTCTGGCAGACCACGGTTATTCTCTGCCCGCCCGGATCGGCATGGAGCTCGACGTCGT
GCCGGTAGCCTTCTTTGAGCGCTACCGCGCCGTATTTCCCAACGCCGACTTCAGCGATGCAACGCCTCTCATCCGGCGGG
TCAGGATGATCAAGAGCAAGTACGAGATTCATCTCCTCCAGGATGCCGCAGTCCAGGTCGACAAGGTCCATCGTCGCGCC
ATGGAGGTCATCCGTGAGGGGATGACCGATCTGGAACTTGCGGCGGAACTGGAGTTCACTGCCCGGAAAGAAGGTCACCA
GGGGCTCGTCCGGATGCGCTCTTTCAATTCTGAGCTGTTTTACGCTCATATTTTTTCAGGGACCGATACAGCGGTCCCTG
CCTATGTGGATACCCCCCTCGGAGGACTTGGGCTCAATCCCTCGTTCGGTCAGGGGGCCGGGCTCAAGCGGATCGAACGC
AATGAGCCGATCATCGTCGATTTCGCCGGTTGCGTTGACGGCTACCTGGTGGACCAGACACGCGTCCTGGCCATCGGAGG
GATTTCCGATCGGTTGCGTCGTGCATACGATGACATGATCAGGGTTCAGGAGCGGATGATCACGCTGGCTCTCCCCGGCA
CGCCGTGGGGCGATGTCTATGAGGGGTGTCGCACTCTGGCTGAGGAGCTGGGGTATGCCGACAGCTTCATGGGCTCCCGT
GGCGCCCAGGTTTCCTTTATCGGTCACGGCATCGGCATCGAGATAGACGAATATCCGTTCATTGCGCGTGGCTTCTCCGA
AATGGTCCTTGAGCCGGGCATGGTTTTCGCTTTCGAGCCGAAGGTCGTTTTCCCGGGCGAAGGAGCCATCGGGATCGAAA
ATACCTTTTATATCTCAAACTATGAAGGGCTCAAGCAGCTGACATTCTCGGACCAGGAACTGGTCATTCTCTGA

Upstream 100 bases:

>100_bases
CCTGGGCGGACGCAAGCGGCGGCGCCTGGAGAAGGAGGCGCGACGTCGCCGTCAGTCGGACGGGGAATGACGCCAAGGTA
ACGCACACAGCGAGGTTTTC

Downstream 100 bases:

>100_bases
CAGCAGTCACTCACCCCTCCGGTGGGACGTCACCTTGACCGAGGTGAAACGTCCCGCCCCACCCCCCCTGATTAGCGCCG
GCCGTCGCGCCCCTTGTTGC

Product: xaa-pro dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRITPREELDYRISRLQTYMAGAGLDAVIIVQNADLFYFTGTIQSGNLYVPVEGDPIYMVRKEHSRARMESGLKLVVPFS
SMKNIPGILADHGYSLPARIGMELDVVPVAFFERYRAVFPNADFSDATPLIRRVRMIKSKYEIHLLQDAAVQVDKVHRRA
MEVIREGMTDLELAAELEFTARKEGHQGLVRMRSFNSELFYAHIFSGTDTAVPAYVDTPLGGLGLNPSFGQGAGLKRIER
NEPIIVDFAGCVDGYLVDQTRVLAIGGISDRLRRAYDDMIRVQERMITLALPGTPWGDVYEGCRTLAEELGYADSFMGSR
GAQVSFIGHGIGIEIDEYPFIARGFSEMVLEPGMVFAFEPKVVFPGEGAIGIENTFYISNYEGLKQLTFSDQELVIL

Sequences:

>Translated_397_residues
MRITPREELDYRISRLQTYMAGAGLDAVIIVQNADLFYFTGTIQSGNLYVPVEGDPIYMVRKEHSRARMESGLKLVVPFS
SMKNIPGILADHGYSLPARIGMELDVVPVAFFERYRAVFPNADFSDATPLIRRVRMIKSKYEIHLLQDAAVQVDKVHRRA
MEVIREGMTDLELAAELEFTARKEGHQGLVRMRSFNSELFYAHIFSGTDTAVPAYVDTPLGGLGLNPSFGQGAGLKRIER
NEPIIVDFAGCVDGYLVDQTRVLAIGGISDRLRRAYDDMIRVQERMITLALPGTPWGDVYEGCRTLAEELGYADSFMGSR
GAQVSFIGHGIGIEIDEYPFIARGFSEMVLEPGMVFAFEPKVVFPGEGAIGIENTFYISNYEGLKQLTFSDQELVIL
>Mature_397_residues
MRITPREELDYRISRLQTYMAGAGLDAVIIVQNADLFYFTGTIQSGNLYVPVEGDPIYMVRKEHSRARMESGLKLVVPFS
SMKNIPGILADHGYSLPARIGMELDVVPVAFFERYRAVFPNADFSDATPLIRRVRMIKSKYEIHLLQDAAVQVDKVHRRA
MEVIREGMTDLELAAELEFTARKEGHQGLVRMRSFNSELFYAHIFSGTDTAVPAYVDTPLGGLGLNPSFGQGAGLKRIER
NEPIIVDFAGCVDGYLVDQTRVLAIGGISDRLRRAYDDMIRVQERMITLALPGTPWGDVYEGCRTLAEELGYADSFMGSR
GAQVSFIGHGIGIEIDEYPFIARGFSEMVLEPGMVFAFEPKVVFPGEGAIGIENTFYISNYEGLKQLTFSDQELVIL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=379, Percent_Identity=25.5936675461741, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44294; Mature: 44294

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITPREELDYRISRLQTYMAGAGLDAVIIVQNADLFYFTGTIQSGNLYVPVEGDPIYMV
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCEEEEECCCEEEEE
RKEHSRARMESGLKLVVPFSSMKNIPGILADHGYSLPARIGMELDVVPVAFFERYRAVFP
ECHHHHHHHHCCCEEEEEHHHHCCCCCEECCCCCCCHHHCCCEEEEEHHHHHHHHHHHCC
NADFSDATPLIRRVRMIKSKYEIHLLQDAAVQVDKVHRRAMEVIREGMTDLELAAELEFT
CCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEHH
ARKEGHQGLVRMRSFNSELFYAHIFSGTDTAVPAYVDTPLGGLGLNPSFGQGAGLKRIER
HHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHCC
NEPIIVDFAGCVDGYLVDQTRVLAIGGISDRLRRAYDDMIRVQERMITLALPGTPWGDVY
CCCEEEEECCCCCCEEECCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
EGCRTLAEELGYADSFMGSRGAQVSFIGHGIGIEIDEYPFIARGFSEMVLEPGMVFAFEP
HHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCEEECCCCHHHCCHHHHHCCCCEEEEECC
KVVFPGEGAIGIENTFYISNYEGLKQLTFSDQELVIL
EEEECCCCCCCCCCEEEEECCCCHHHHCCCCCCEEEC
>Mature Secondary Structure
MRITPREELDYRISRLQTYMAGAGLDAVIIVQNADLFYFTGTIQSGNLYVPVEGDPIYMV
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCEEEEECCCEEEEE
RKEHSRARMESGLKLVVPFSSMKNIPGILADHGYSLPARIGMELDVVPVAFFERYRAVFP
ECHHHHHHHHCCCEEEEEHHHHCCCCCEECCCCCCCHHHCCCEEEEEHHHHHHHHHHHCC
NADFSDATPLIRRVRMIKSKYEIHLLQDAAVQVDKVHRRAMEVIREGMTDLELAAELEFT
CCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEHH
ARKEGHQGLVRMRSFNSELFYAHIFSGTDTAVPAYVDTPLGGLGLNPSFGQGAGLKRIER
HHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHCC
NEPIIVDFAGCVDGYLVDQTRVLAIGGISDRLRRAYDDMIRVQERMITLALPGTPWGDVY
CCCEEEEECCCCCCEEECCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
EGCRTLAEELGYADSFMGSRGAQVSFIGHGIGIEIDEYPFIARGFSEMVLEPGMVFAFEP
HHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCEEECCCCHHHCCHHHHHCCCCEEEEECC
KVVFPGEGAIGIENTFYISNYEGLKQLTFSDQELVIL
EEEECCCCCCCCCCEEEEECCCCHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]