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The map label for this gene is ruvA [H]

Identifier: 39996178

GI number: 39996178

Start: 1164434

End: 1165033

Strand: Direct

Name: ruvA [H]

Synonym: GSU1076

Alternate gene names: 39996178

Gene position: 1164434-1165033 (Clockwise)

Preceding gene: 39996177

Following gene: 39996179

Centisome position: 30.53

GC content: 60.0

Gene sequence:

>600_bases
ATGATCGCCCTTCTCACCGGCAGGCTCGCCCATAAATCCCCCGATGCCATCATTATCGATGTGAACGGTGTCGGCTACCG
GGTCCAGATTCCTTTCTCAACCTACTACGAGCTTCCCGAGGAGGGGAAGACAGTTTCCCTTTCGATACATACCCATGTGA
AGGAAGACTCCATTAGCCTCTTCGGCTTCCGAACCCTTGCCGAGAAGGAGTTCTTTCAGCTGCTCATCTCGGTTTCCGGC
ATCGGCCCCAAGATGGCCCGCGACATCCTGTCCAACATCCAGCCGGAGGAACTGGCCGCCGCCATTGTGCAGGGGAATCT
CGTGAGGCTCTCATCCATACCCGGCATCGGCAAAAAGACCGCCGAGCGGCTGGTGCTGGAACTCAAGGAAAAGGTCCGGA
AAATGGATGTGGCGCCGTCGGCCCAGGAGGCGCCCTCCAGCGAAGCCCCCGCCGAGGTGGCTGACGACGTGGCCTCGGCC
CTTGTGAACCTCGGCTATAAGGAGGCGGTGGTCCGGAAGGTGTTGGCCGAGATGAGCATCGAGCCCGATGCCTCCACGGA
GGCGGTGCTTCGGCAGGCCCTCAAGGTGTTGATGAAATAG

Upstream 100 bases:

>100_bases
ATCTCCCCGAGATCGCCCAGGCCGATGCCTCCGATGCCTTGGCCGTAGCGGTCTGCCACGCCAATTCAGCAGTGATGAAA
TCCGTGCTCCGGAGCATCCG

Downstream 100 bases:

>100_bases
CCCATGACGACTCGAACGATAAGCCCTGAGAAGACCGACGACGACTACGTCGAATCATCCCTGCGCCCCCGCGCCCTGGA
AGATTACATTGGCCAGGAGA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIALLTGRLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPEEGKTVSLSIHTHVKEDSISLFGFRTLAEKEFFQLLISVSG
IGPKMARDILSNIQPEELAAAIVQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSAQEAPSSEAPAEVADDVASA
LVNLGYKEAVVRKVLAEMSIEPDASTEAVLRQALKVLMK

Sequences:

>Translated_199_residues
MIALLTGRLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPEEGKTVSLSIHTHVKEDSISLFGFRTLAEKEFFQLLISVSG
IGPKMARDILSNIQPEELAAAIVQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSAQEAPSSEAPAEVADDVASA
LVNLGYKEAVVRKVLAEMSIEPDASTEAVLRQALKVLMK
>Mature_199_residues
MIALLTGRLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPEEGKTVSLSIHTHVKEDSISLFGFRTLAEKEFFQLLISVSG
IGPKMARDILSNIQPEELAAAIVQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSAQEAPSSEAPAEVADDVASA
LVNLGYKEAVVRKVLAEMSIEPDASTEAVLRQALKVLMK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=36.81592039801, Blast_Score=138, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21565; Mature: 21565

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLTGRLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPEEGKTVSLSIHTHVKEDSISL
CEEEEECHHHCCCCCEEEEEECCCCEEEEECHHHHHCCCCCCCEEEEEEEEECCCCCCHH
FGFRTLAEKEFFQLLISVSGIGPKMARDILSNIQPEELAAAIVQGNLVRLSSIPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCCCHHH
AERLVLELKEKVRKMDVAPSAQEAPSSEAPAEVADDVASALVNLGYKEAVVRKVLAEMSI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EPDASTEAVLRQALKVLMK
CCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIALLTGRLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPEEGKTVSLSIHTHVKEDSISL
CEEEEECHHHCCCCCEEEEEECCCCEEEEECHHHHHCCCCCCCEEEEEEEEECCCCCCHH
FGFRTLAEKEFFQLLISVSGIGPKMARDILSNIQPEELAAAIVQGNLVRLSSIPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCCCHHH
AERLVLELKEKVRKMDVAPSAQEAPSSEAPAEVADDVASALVNLGYKEAVVRKVLAEMSI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EPDASTEAVLRQALKVLMK
CCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA