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The map label for this gene is ruvB [H]

Identifier: 39996179

GI number: 39996179

Start: 1165037

End: 1166053

Strand: Direct

Name: ruvB [H]

Synonym: GSU1077

Alternate gene names: 39996179

Gene position: 1165037-1166053 (Clockwise)

Preceding gene: 39996178

Following gene: 39996180

Centisome position: 30.55

GC content: 63.13

Gene sequence:

>1017_bases
ATGACGACTCGAACGATAAGCCCTGAGAAGACCGACGACGACTACGTCGAATCATCCCTGCGCCCCCGCGCCCTGGAAGA
TTACATTGGCCAGGAGAAGGCCAAGGGGAACCTGCGGGTCTTCATCGACGCGGCCCGAAAGCGCGGCGAGGCCCTGGATC
ACGTGCTGCTCTATGGTCCGCCGGGACTGGGGAAGACCACGCTTGCCAACATCATTGCCTGCGAGATGGGGGTAAACATC
AAGTCCACGTCGGGTCCAGTCATCGAGCGTCCGGGCGATCTGGCGGCAATCCTCACCAACCTGGAGCCCCACGACGTCCT
CTTCATCGATGAGATCCACCGCCTCTCCCATGTGGTGGAGGAGATACTCTATCCGGCCATGGAGGATTTCCAGCTCGACA
TCATCATCGGTCAAGGCCCAAGTGCCCGCACCATCAAGCTGGATCTTCCCCGGTTCACCCTCGTGGGGGCCACCACCCGC
GCCGGCCTTCTCTCGTCGCCACTGCGGGATCGCTTTGGAGTCATCTCGCGCCTGGAGTTCTACACCGATGCAGAGCTTTC
CACCATCGTCACCAGGTCGGCGCATATCCTCGATATCCAGATCGAGCCTGACGGTGCCCGGGAGCTGGCACGCCGCAGCC
GGGGAACACCCCGGATCGCCAACCGTCTCCTGCGTCGGGTCAGGGACTTTGCCCAGGTCCGGGCCGATGGCGTCATCTCC
GCTCAGGTGGTGGACGAATCCCTCAAGCTCCTGGAGATCGACGAAAAGGGGTTCGATCAGATGGACCGCACCATCATGCT
GACGATCATCGACAAGTTCGGCGGCGGGCCCGTGGGGCTCGACACCATAGCCGCGGCCATCGGCGAGGAACGCGATACCA
TCGAGGATGTCTACGAGCCGTTCCTGATCCAGCACGGTTTCATTAACCGCACCCCCCGGGGCCGCGTGGCCACGAAGTCC
GCCTATGAGCACTTCGGCCGCATTGCGCCCGCGCCCGGGCAAGGCGCGCTCTTCTAG

Upstream 100 bases:

>100_bases
GGCGGTGGTCCGGAAGGTGTTGGCCGAGATGAGCATCGAGCCCGATGCCTCCACGGAGGCGGTGCTTCGGCAGGCCCTCA
AGGTGTTGATGAAATAGCCC

Downstream 100 bases:

>100_bases
GCCGTTTCCCGCCATGCAACTCGTCTTCGACTTTCCCGTCACCCCCAAATACTCGTTCGACAATTTCGTGATCTGTGCCG
GCAACGAGACTGCCTGCCGT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTTRTISPEKTDDDYVESSLRPRALEDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPPGLGKTTLANIIACEMGVNI
KSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPRFTLVGATTR
AGLLSSPLRDRFGVISRLEFYTDAELSTIVTRSAHILDIQIEPDGARELARRSRGTPRIANRLLRRVRDFAQVRADGVIS
AQVVDESLKLLEIDEKGFDQMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPFLIQHGFINRTPRGRVATKS
AYEHFGRIAPAPGQGALF

Sequences:

>Translated_338_residues
MTTRTISPEKTDDDYVESSLRPRALEDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPPGLGKTTLANIIACEMGVNI
KSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPRFTLVGATTR
AGLLSSPLRDRFGVISRLEFYTDAELSTIVTRSAHILDIQIEPDGARELARRSRGTPRIANRLLRRVRDFAQVRADGVIS
AQVVDESLKLLEIDEKGFDQMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPFLIQHGFINRTPRGRVATKS
AYEHFGRIAPAPGQGALF
>Mature_337_residues
TTRTISPEKTDDDYVESSLRPRALEDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPPGLGKTTLANIIACEMGVNIK
STSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPRFTLVGATTRA
GLLSSPLRDRFGVISRLEFYTDAELSTIVTRSAHILDIQIEPDGARELARRSRGTPRIANRLLRRVRDFAQVRADGVISA
QVVDESLKLLEIDEKGFDQMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPFLIQHGFINRTPRGRVATKSA
YEHFGRIAPAPGQGALF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=318, Percent_Identity=65.7232704402516, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37350; Mature: 37219

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRTISPEKTDDDYVESSLRPRALEDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGP
CCCCCCCCCCCCHHHHHHCCCCHHHHHHHCHHCCCCCEEEEEEEHHHCCHHHCEEEEECC
PGLGKTTLANIIACEMGVNIKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVE
CCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDIIIGQGPSARTIKLDLPRFTLVGATTRAGLLSSPLRDRFGVISRLEF
HHHHHCCCCEEEEEEEECCCCCEEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHHH
YTDAELSTIVTRSAHILDIQIEPDGARELARRSRGTPRIANRLLRRVRDFAQVRADGVIS
HCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEE
AQVVDESLKLLEIDEKGFDQMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEP
HHHHHCCHHEEEECCCCHHHHHHEEEEEEHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FLIQHGFINRTPRGRVATKSAYEHFGRIAPAPGQGALF
HHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTRTISPEKTDDDYVESSLRPRALEDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGP
CCCCCCCCCCCHHHHHHCCCCHHHHHHHCHHCCCCCEEEEEEEHHHCCHHHCEEEEECC
PGLGKTTLANIIACEMGVNIKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVE
CCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDIIIGQGPSARTIKLDLPRFTLVGATTRAGLLSSPLRDRFGVISRLEF
HHHHHCCCCEEEEEEEECCCCCEEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHHH
YTDAELSTIVTRSAHILDIQIEPDGARELARRSRGTPRIANRLLRRVRDFAQVRADGVIS
HCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEE
AQVVDESLKLLEIDEKGFDQMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEP
HHHHHCCHHEEEECCCCHHHHHHEEEEEEHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FLIQHGFINRTPRGRVATKSAYEHFGRIAPAPGQGALF
HHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA