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The map label for this gene is tsr [C]

Identifier: 39996143

GI number: 39996143

Start: 1127555

End: 1129180

Strand: Direct

Name: tsr [C]

Synonym: GSU1041

Alternate gene names: 39996143

Gene position: 1127555-1129180 (Clockwise)

Preceding gene: 39996141

Following gene: 39996144

Centisome position: 29.56

GC content: 62.05

Gene sequence:

>1626_bases
ATGTTCATGAGAAACTGGAAAATCGGGACGAAACTGGCAACCGGGTTCGGAGGACTTCTTCTGCTGCTGGTGATCTTCAC
CACAGTAACCATCATTTCCATCCGGTTCGTGAAGACGAGCACGAGCCAGATCAGGACCGAGAGCCTTCCCTATGCCTTGC
TCGCCGAGGAAATGGCGTTCGAGGTGGTTCAGGTCCAGCAGTTCCTGACCGACGTGGGGGCGACGCGGGAGCCCGATGCT
TATGCCGAGGCGGACGCGGCCGCGGCAAATTTCCGCAAGTCTCTGAAGCAGTTCGAAGACATGTACCGCCGCGAGAATGA
TACCGCTGCCCTCCAATCCGTTGAAAAGATGGAGAAGGACTTTGAGTCCTTTTATCAGCTGGGTCGACGGATGGCCGAGG
CTTATATGGCCGAGGGGACGGAAGCGGGTAACCGTTTGATGGGCGATTTCGACAAGGTGTCAACGGTTCTTGCCGAAGAC
ATGAGAACATTCAAGGAGGGGCAGGTCAGAGAAGCCAACCACATGACCGCGTCTGTGGACGAAACGCTCGGCGGGCTGGA
AAAGGTCATTATCGCCCTTGCCGCTGCCGGGATCATTGTGGGGCTTTTCGCCTCCTGGTTCATCGGGAAAGCCATTTCCG
CCCCCCTCGGCAAGGCGGTGTCCGCCATCGACCGGATCGCTTCGGGCGATCTCACCATCAGGATTCCGGTCACGGGAAGC
GATGAAACCGGGGCGCTCGCCGTATCCGTCAACCGCATGGCGGACGATATGGGTACGGCCATGGCAGCCCTGGCCAATGC
ATCGTCACATCTGGCCTCGGCCTCGGTGGAGCTTGCGGTGCAGGCGGACCAGATGGCCAAGGGGGCCGAGGAAGTGGCGG
CCCAGACGGGAACCGTTGCCGCGGCGAGCGAGGAAATGGCCGCAACGTCCCACGAGATTGCCATGAACTGTTCCCATGCC
GCCGAAAGCTCCCGGAGGGCCAACGACCGTGCATCGGCAGGCTCCGATGTCATCCGTCGCACTGTCGAGGGGATGCATCG
CATTGCCGAAAAGGTTCAGCGCTCCTCCGAGAGCGTTGCCGGACTGGGGGCCCGCAGCGACCAGATCGGCCAGATTGTTT
CGGTTATCGAAGACATCGCGGACCAGACGAACCTGCTGGCCCTCAACGCCGCCATCGAGGCGGCCCGGGCCGGGGAGCAG
GGGCGGGGGTTCGCCGTGGTGGCCGACGAGGTACGTGCGCTGGCAGAGCGAACCGGCAAGGCGACGCGTGAGATCGCCCA
GATGATCCGCTCCATCCAGCAGGAAACCGAGGGTGCGGTCAAGGCCATGGAAGAAGGGGTGGCGGAAGTCTCTGCCGGCA
AGGAGGACGCCCAGCAATCCGCCGGTGCTCTCCGGGAGATCGTCGAGCAGATCGAGGCCATGACGACACAGATCAATCAG
ATCGCCGTCGCCTCCGAGCAGCAGAACGCCACCACCGATCAGATCACCATGAACCTCCAGCAGGTTTCGAGCGTTATCGA
GGCGTCCTCCCGCGGTTCCGAGGAAACCGCCAACGCGGCCCATACCCTCTCGGCGCTCTCCGAAGAACTCCAGAGCATTG
TGGGGCGGTTTCGCACGGCGGCTTAG

Upstream 100 bases:

>100_bases
GTGAAGTCCGCTCTTCATGTGCATTGTTTTATGCATGATTACGTCGGCTTTATTTGTGATGATGATTAATTTTTTCTGTT
TATTGGAAGGAGATCGCCGC

Downstream 100 bases:

>100_bases
CGGACAGGGTCGGCAGGAGGCGCCGACCTTTGCGGGATAGATCACGAAGGGAGAACGTGATGGTTGTATGGAAGGATGAG
TATCTGATCGGGGTCGAGCA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MFMRNWKIGTKLATGFGGLLLLLVIFTTVTIISIRFVKTSTSQIRTESLPYALLAEEMAFEVVQVQQFLTDVGATREPDA
YAEADAAAANFRKSLKQFEDMYRRENDTAALQSVEKMEKDFESFYQLGRRMAEAYMAEGTEAGNRLMGDFDKVSTVLAED
MRTFKEGQVREANHMTASVDETLGGLEKVIIALAAAGIIVGLFASWFIGKAISAPLGKAVSAIDRIASGDLTIRIPVTGS
DETGALAVSVNRMADDMGTAMAALANASSHLASASVELAVQADQMAKGAEEVAAQTGTVAAASEEMAATSHEIAMNCSHA
AESSRRANDRASAGSDVIRRTVEGMHRIAEKVQRSSESVAGLGARSDQIGQIVSVIEDIADQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAERTGKATREIAQMIRSIQQETEGAVKAMEEGVAEVSAGKEDAQQSAGALREIVEQIEAMTTQINQ
IAVASEQQNATTDQITMNLQQVSSVIEASSRGSEETANAAHTLSALSEELQSIVGRFRTAA

Sequences:

>Translated_541_residues
MFMRNWKIGTKLATGFGGLLLLLVIFTTVTIISIRFVKTSTSQIRTESLPYALLAEEMAFEVVQVQQFLTDVGATREPDA
YAEADAAAANFRKSLKQFEDMYRRENDTAALQSVEKMEKDFESFYQLGRRMAEAYMAEGTEAGNRLMGDFDKVSTVLAED
MRTFKEGQVREANHMTASVDETLGGLEKVIIALAAAGIIVGLFASWFIGKAISAPLGKAVSAIDRIASGDLTIRIPVTGS
DETGALAVSVNRMADDMGTAMAALANASSHLASASVELAVQADQMAKGAEEVAAQTGTVAAASEEMAATSHEIAMNCSHA
AESSRRANDRASAGSDVIRRTVEGMHRIAEKVQRSSESVAGLGARSDQIGQIVSVIEDIADQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAERTGKATREIAQMIRSIQQETEGAVKAMEEGVAEVSAGKEDAQQSAGALREIVEQIEAMTTQINQ
IAVASEQQNATTDQITMNLQQVSSVIEASSRGSEETANAAHTLSALSEELQSIVGRFRTAA
>Mature_541_residues
MFMRNWKIGTKLATGFGGLLLLLVIFTTVTIISIRFVKTSTSQIRTESLPYALLAEEMAFEVVQVQQFLTDVGATREPDA
YAEADAAAANFRKSLKQFEDMYRRENDTAALQSVEKMEKDFESFYQLGRRMAEAYMAEGTEAGNRLMGDFDKVSTVLAED
MRTFKEGQVREANHMTASVDETLGGLEKVIIALAAAGIIVGLFASWFIGKAISAPLGKAVSAIDRIASGDLTIRIPVTGS
DETGALAVSVNRMADDMGTAMAALANASSHLASASVELAVQADQMAKGAEEVAAQTGTVAAASEEMAATSHEIAMNCSHA
AESSRRANDRASAGSDVIRRTVEGMHRIAEKVQRSSESVAGLGARSDQIGQIVSVIEDIADQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAERTGKATREIAQMIRSIQQETEGAVKAMEEGVAEVSAGKEDAQQSAGALREIVEQIEAMTTQINQ
IAVASEQQNATTDQITMNLQQVSSVIEASSRGSEETANAAHTLSALSEELQSIVGRFRTAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=422, Percent_Identity=30.0947867298578, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788195, Length=303, Percent_Identity=32.6732673267327, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787690, Length=378, Percent_Identity=29.1005291005291, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1788194, Length=343, Percent_Identity=32.3615160349854, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789453, Length=326, Percent_Identity=28.2208588957055, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57575; Mature: 57575

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMRNWKIGTKLATGFGGLLLLLVIFTTVTIISIRFVKTSTSQIRTESLPYALLAEEMAF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHCCCHHHHHHHHHH
EVVQVQQFLTDVGATREPDAYAEADAAAANFRKSLKQFEDMYRRENDTAALQSVEKMEKD
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FESFYQLGRRMAEAYMAEGTEAGNRLMGDFDKVSTVLAEDMRTFKEGQVREANHMTASVD
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
ETLGGLEKVIIALAAAGIIVGLFASWFIGKAISAPLGKAVSAIDRIASGDLTIRIPVTGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
DETGALAVSVNRMADDMGTAMAALANASSHLASASVELAVQADQMAKGAEEVAAQTGTVA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHCCCHH
AASEEMAATSHEIAMNCSHAAESSRRANDRASAGSDVIRRTVEGMHRIAEKVQRSSESVA
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGARSDQIGQIVSVIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTGK
CCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCH
ATREIAQMIRSIQQETEGAVKAMEEGVAEVSAGKEDAQQSAGALREIVEQIEAMTTQINQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVASEQQNATTDQITMNLQQVSSVIEASSRGSEETANAAHTLSALSEELQSIVGRFRTA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure
MFMRNWKIGTKLATGFGGLLLLLVIFTTVTIISIRFVKTSTSQIRTESLPYALLAEEMAF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHCCCHHHHHHHHHH
EVVQVQQFLTDVGATREPDAYAEADAAAANFRKSLKQFEDMYRRENDTAALQSVEKMEKD
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FESFYQLGRRMAEAYMAEGTEAGNRLMGDFDKVSTVLAEDMRTFKEGQVREANHMTASVD
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
ETLGGLEKVIIALAAAGIIVGLFASWFIGKAISAPLGKAVSAIDRIASGDLTIRIPVTGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
DETGALAVSVNRMADDMGTAMAALANASSHLASASVELAVQADQMAKGAEEVAAQTGTVA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHCCCHH
AASEEMAATSHEIAMNCSHAAESSRRANDRASAGSDVIRRTVEGMHRIAEKVQRSSESVA
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGARSDQIGQIVSVIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTGK
CCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCH
ATREIAQMIRSIQQETEGAVKAMEEGVAEVSAGKEDAQQSAGALREIVEQIEAMTTQINQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVASEQQNATTDQITMNLQQVSSVIEASSRGSEETANAAHTLSALSEELQSIVGRFRTA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA