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The map label for this gene is yciR [C]

Identifier: 39996139

GI number: 39996139

Start: 1121523

End: 1123922

Strand: Direct

Name: yciR [C]

Synonym: GSU1037

Alternate gene names: 39996139

Gene position: 1121523-1123922 (Clockwise)

Preceding gene: 39996137

Following gene: 39996140

Centisome position: 29.4

GC content: 61.5

Gene sequence:

>2400_bases
ATGGGCAGGGAGGGCAGAGGTACACGACAAAGGAATATAATGCGGTTGGTCAGCCAGCCGGGCTTGGATCCCAAAGCGTC
GGTCCCTTCATTCGACCATGACGCCCGCCCGGTGCCTGCCACCTCGGCCGGCGTCTCCCGGCCGGCGATAGATCCCCCGG
CCGAATGGACCGTTCGCCAGTACATACGTGAGAAAAAGGATCAGCGGTTTCCCTCTCCCAGGGGCCAGCACCGCTGTTTT
TCAGGGCTTGACGCCCTGTGCGGCATGAAGAGCGAGGTGCCGGAACGGCCGACGGTCGTTCTGATCATCGAGGATGACCG
GCAGGTTCGCCTCCTTGCCAGGGATGTGCTTGAGGAAGCAGGGTTTGTGGTGGAAGAGGCATGTGACGGCCGGGAAGGCG
TGGTCAAGTTCGGTCGGGTACGGCCCGACGTGGTGCTGCTCGACGTGATCCTCCCCTACATGAACGGCATGACCGTGTGC
AGGGTCTTGCGGGAGATGCCCGGCGGCGAGCGGGTCCCCGTCGTCATGATGACGGCTCTGGGCGATTCGGATGCGGTTCG
GGAGGCGTTCGACGCGGGAGCCACCTTTTTTGTCCCGAAACCGATCAACCTATCGACCCTCCCCGAACACCTCACCTACC
TTGTCAGATCAAGCCGTGTCCTCCAGGAACTCCATGAAAGCGAAGCGCAAAACCGGGCATTGCTGAACGCCATTCCGGAC
ATGATGCTCCATGTCTGCCGCGAGGGAACCATTCTCGACTTCCGTGCCGGCAACGGTTGTGCCTATGCGGCGTTCGGGGG
AAACCTCCGCGGCAGGACCATTGCCGATCTTCTTCCCCCCGGCGCGGCGGCCCAGTTCATGGCTCAAGTCGGACACGCGC
TTGCCACGGGAACCATGATGGTCTGCGAGTATGAGCTGGAGGGCCCCGGCGGTCTCAACACCCACGAGGCCAGGATCGTT
GCCAACGGTACCGGCACGGTGCTCGCCATCGTGCGCGACGTGACGGAGCGGCGGCAGTCGGAGGAGATGATCCGCTACCT
GGCGCATCACGACAGCCTCACGGGACTCCCCAACCGGATATTTTTCGGCGAAATGCTGGAGCTCGTTCTTTCCCGCGCCC
GGCGCGACGGCAAGCAGGTTGCCATTCTTTTCGTGGACCTGGACGACTTCAAGCTCATCAACGACACCCTCGGCCACGCC
GCCGGTGACCACCTGCTGCGGGAAGCTGCCCAGCGCCTCAAGGGATGCGTCCGGAGCAGCGACTACGTGGCCAGCGGGGC
GGAGAGCGGCCTGTGCGGCAATATCGCCCGCTTCGGCGGCGACGAGTTCATCCTTTCATTGGGAAACCTGGACTCCGTTG
ACGATGTGGTGGCGGTGACGCAGCGGATTATCAGCGAGTTTTCCCGGGAGTTCCGGATTGATGGTCATGAGATATTCGTA
TCAGTGAGCATCGGCATCTCCATGTATCCCGACGATGCCGAAGATACCGGCTCCTTGGTCAGAAACGCCGACATGGCCAT
GTTTGCCGCAAAGGAAGAGGGAGGACCGTCGTTCCGCTTCTTTACCCGGGGCATGAACGAAGCCGCCCAGCAGCGTCTCT
CCATAGAACTCAGCCTGCGCAAGGCGTTGGAACGGGGAGAGATCTTCGTCCACTATCAGCCGAAAGTTGACCTGTCCTGT
GGGGAGATAACCGGTTTCGAGGCCCTTGCCCGTTGGCACCATCCGGAACTCGGACTGATCCCTCCCGATACGTTCATTCC
CCTGGCGGAAAAGAACGGCCTGATCGTCCGGATCGGCGAGTGGGTGCTGAGAGCCGCCTGTGCCCAGGCCAGGACATGGA
TCGACGAAGGCTTCTCCGATTTGTGCATGGCCATTAACCTGTCGAGTCACCAGTTCACCAGCGGCAACCTCACCTCTATG
GTAAAAGAGGTGCTTGACGAGACGGAACTGCCTCCCTCCTGTCTAGAGTTCGAAATCACCGAGGGAATCCTCATGGAGCG
GACCGAGAAAACCATGCGGATCCTTTCCGAGCTGCGGGACATGGGAGTCAGGATATCCATCGACGATTTCGGCACCGGCT
ACTCGTCGCTGGGGTATCTCAAGCGCTTCCCCGTGAACACGGTCAAGATCGACCGCTCATTCGTGCGGGAAATCGATTCA
CCCCACGAGGATGCGGCGATCATCAAGGCCATCATTGCCGTCGCGCGTAACCTGAATCTCCAGGTGGTGGCCGAAGGGGT
CGAAAGCCATCGACAGACGGAATTTCTCCTTGCCCATGGCTGTAACGAGGCTCAGGGGTTCCTCTTCGGCAAGCCGGTGC
ATCCCGATGAGGCGAGCCTGATGCTCCGGGCCGGGAGATGGCGCGACGCGCCCGCACGTGCCCTGGCGCGGGGAAGGTGA

Upstream 100 bases:

>100_bases
TGTTTCGATAGGGCGATTCTGTTCACGACGGCACGACACTTGTAATCCGAAAGACAGAAGCTCGCACTGCATGATGTCAT
GATATCGGGGAGGGTACCCA

Downstream 100 bases:

>100_bases
GGCGGGCGCGTCGGCTGAACTGCCGAACATTATGAAGAGGAGGGGAGTGATGGGGCTGCGGAAGACGCAGCCCCTTTTTT
GCGTCGAATCTCCCGATTTG

Product: sensory box/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 799; Mature: 798

Protein sequence:

>799_residues
MGREGRGTRQRNIMRLVSQPGLDPKASVPSFDHDARPVPATSAGVSRPAIDPPAEWTVRQYIREKKDQRFPSPRGQHRCF
SGLDALCGMKSEVPERPTVVLIIEDDRQVRLLARDVLEEAGFVVEEACDGREGVVKFGRVRPDVVLLDVILPYMNGMTVC
RVLREMPGGERVPVVMMTALGDSDAVREAFDAGATFFVPKPINLSTLPEHLTYLVRSSRVLQELHESEAQNRALLNAIPD
MMLHVCREGTILDFRAGNGCAYAAFGGNLRGRTIADLLPPGAAAQFMAQVGHALATGTMMVCEYELEGPGGLNTHEARIV
ANGTGTVLAIVRDVTERRQSEEMIRYLAHHDSLTGLPNRIFFGEMLELVLSRARRDGKQVAILFVDLDDFKLINDTLGHA
AGDHLLREAAQRLKGCVRSSDYVASGAESGLCGNIARFGGDEFILSLGNLDSVDDVVAVTQRIISEFSREFRIDGHEIFV
SVSIGISMYPDDAEDTGSLVRNADMAMFAAKEEGGPSFRFFTRGMNEAAQQRLSIELSLRKALERGEIFVHYQPKVDLSC
GEITGFEALARWHHPELGLIPPDTFIPLAEKNGLIVRIGEWVLRAACAQARTWIDEGFSDLCMAINLSSHQFTSGNLTSM
VKEVLDETELPPSCLEFEITEGILMERTEKTMRILSELRDMGVRISIDDFGTGYSSLGYLKRFPVNTVKIDRSFVREIDS
PHEDAAIIKAIIAVARNLNLQVVAEGVESHRQTEFLLAHGCNEAQGFLFGKPVHPDEASLMLRAGRWRDAPARALARGR

Sequences:

>Translated_799_residues
MGREGRGTRQRNIMRLVSQPGLDPKASVPSFDHDARPVPATSAGVSRPAIDPPAEWTVRQYIREKKDQRFPSPRGQHRCF
SGLDALCGMKSEVPERPTVVLIIEDDRQVRLLARDVLEEAGFVVEEACDGREGVVKFGRVRPDVVLLDVILPYMNGMTVC
RVLREMPGGERVPVVMMTALGDSDAVREAFDAGATFFVPKPINLSTLPEHLTYLVRSSRVLQELHESEAQNRALLNAIPD
MMLHVCREGTILDFRAGNGCAYAAFGGNLRGRTIADLLPPGAAAQFMAQVGHALATGTMMVCEYELEGPGGLNTHEARIV
ANGTGTVLAIVRDVTERRQSEEMIRYLAHHDSLTGLPNRIFFGEMLELVLSRARRDGKQVAILFVDLDDFKLINDTLGHA
AGDHLLREAAQRLKGCVRSSDYVASGAESGLCGNIARFGGDEFILSLGNLDSVDDVVAVTQRIISEFSREFRIDGHEIFV
SVSIGISMYPDDAEDTGSLVRNADMAMFAAKEEGGPSFRFFTRGMNEAAQQRLSIELSLRKALERGEIFVHYQPKVDLSC
GEITGFEALARWHHPELGLIPPDTFIPLAEKNGLIVRIGEWVLRAACAQARTWIDEGFSDLCMAINLSSHQFTSGNLTSM
VKEVLDETELPPSCLEFEITEGILMERTEKTMRILSELRDMGVRISIDDFGTGYSSLGYLKRFPVNTVKIDRSFVREIDS
PHEDAAIIKAIIAVARNLNLQVVAEGVESHRQTEFLLAHGCNEAQGFLFGKPVHPDEASLMLRAGRWRDAPARALARGR
>Mature_798_residues
GREGRGTRQRNIMRLVSQPGLDPKASVPSFDHDARPVPATSAGVSRPAIDPPAEWTVRQYIREKKDQRFPSPRGQHRCFS
GLDALCGMKSEVPERPTVVLIIEDDRQVRLLARDVLEEAGFVVEEACDGREGVVKFGRVRPDVVLLDVILPYMNGMTVCR
VLREMPGGERVPVVMMTALGDSDAVREAFDAGATFFVPKPINLSTLPEHLTYLVRSSRVLQELHESEAQNRALLNAIPDM
MLHVCREGTILDFRAGNGCAYAAFGGNLRGRTIADLLPPGAAAQFMAQVGHALATGTMMVCEYELEGPGGLNTHEARIVA
NGTGTVLAIVRDVTERRQSEEMIRYLAHHDSLTGLPNRIFFGEMLELVLSRARRDGKQVAILFVDLDDFKLINDTLGHAA
GDHLLREAAQRLKGCVRSSDYVASGAESGLCGNIARFGGDEFILSLGNLDSVDDVVAVTQRIISEFSREFRIDGHEIFVS
VSIGISMYPDDAEDTGSLVRNADMAMFAAKEEGGPSFRFFTRGMNEAAQQRLSIELSLRKALERGEIFVHYQPKVDLSCG
EITGFEALARWHHPELGLIPPDTFIPLAEKNGLIVRIGEWVLRAACAQARTWIDEGFSDLCMAINLSSHQFTSGNLTSMV
KEVLDETELPPSCLEFEITEGILMERTEKTMRILSELRDMGVRISIDDFGTGYSSLGYLKRFPVNTVKIDRSFVREIDSP
HEDAAIIKAIIAVARNLNLQVVAEGVESHRQTEFLLAHGCNEAQGFLFGKPVHPDEASLMLRAGRWRDAPARALARGR

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=464, Percent_Identity=38.5775862068966, Blast_Score=339, Evalue=5e-94,
Organism=Escherichia coli, GI87081921, Length=443, Percent_Identity=33.8600451467269, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI226510982, Length=438, Percent_Identity=29.9086757990868, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI87081743, Length=233, Percent_Identity=36.480686695279, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1790496, Length=281, Percent_Identity=33.0960854092527, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1787055, Length=346, Percent_Identity=30.0578034682081, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1788502, Length=255, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=36.1344537815126, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1786507, Length=254, Percent_Identity=31.496062992126, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI87081980, Length=246, Percent_Identity=32.520325203252, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788381, Length=443, Percent_Identity=27.313769751693, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788849, Length=450, Percent_Identity=25.5555555555556, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87082096, Length=239, Percent_Identity=31.3807531380753, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI145693134, Length=237, Percent_Identity=31.2236286919831, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87081881, Length=296, Percent_Identity=27.3648648648649, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI87081977, Length=181, Percent_Identity=32.0441988950276, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789650, Length=504, Percent_Identity=19.6428571428571, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=171, Percent_Identity=36.2573099415205, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=25.414364640884, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787262, Length=174, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1788550, Length=156, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787410, Length=155, Percent_Identity=30.3225806451613, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87081974, Length=108, Percent_Identity=37.037037037037, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 88192; Mature: 88061

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGREGRGTRQRNIMRLVSQPGLDPKASVPSFDHDARPVPATSAGVSRPAIDPPAEWTVRQ
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
YIREKKDQRFPSPRGQHRCFSGLDALCGMKSEVPERPTVVLIIEDDRQVRLLARDVLEEA
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHC
GFVVEEACDGREGVVKFGRVRPDVVLLDVILPYMNGMTVCRVLREMPGGERVPVVMMTAL
CCCHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEEEC
GDSDAVREAFDAGATFFVPKPINLSTLPEHLTYLVRSSRVLQELHESEAQNRALLNAIPD
CCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLHVCREGTILDFRAGNGCAYAAFGGNLRGRTIADLLPPGAAAQFMAQVGHALATGTMM
HHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEE
VCEYELEGPGGLNTHEARIVANGTGTVLAIVRDVTERRQSEEMIRYLAHHDSLTGLPNRI
EEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
FFGEMLELVLSRARRDGKQVAILFVDLDDFKLINDTLGHAAGDHLLREAAQRLKGCVRSS
HHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DYVASGAESGLCGNIARFGGDEFILSLGNLDSVDDVVAVTQRIISEFSREFRIDGHEIFV
CHHHCCCCCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SVSIGISMYPDDAEDTGSLVRNADMAMFAAKEEGGPSFRFFTRGMNEAAQQRLSIELSLR
EEEECEEECCCCCHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KALERGEIFVHYQPKVDLSCGEITGFEALARWHHPELGLIPPDTFIPLAEKNGLIVRIGE
HHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEHHH
WVLRAACAQARTWIDEGFSDLCMAINLSSHQFTSGNLTSMVKEVLDETELPPSCLEFEIT
HHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEEHH
EGILMERTEKTMRILSELRDMGVRISIDDFGTGYSSLGYLKRFPVNTVKIDRSFVREIDS
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEEECHHHHHHCCC
PHEDAAIIKAIIAVARNLNLQVVAEGVESHRQTEFLLAHGCNEAQGFLFGKPVHPDEASL
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHH
MLRAGRWRDAPARALARGR
HEECCCCCCCHHHHHHCCC
>Mature Secondary Structure 
GREGRGTRQRNIMRLVSQPGLDPKASVPSFDHDARPVPATSAGVSRPAIDPPAEWTVRQ
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
YIREKKDQRFPSPRGQHRCFSGLDALCGMKSEVPERPTVVLIIEDDRQVRLLARDVLEEA
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHC
GFVVEEACDGREGVVKFGRVRPDVVLLDVILPYMNGMTVCRVLREMPGGERVPVVMMTAL
CCCHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEEEC
GDSDAVREAFDAGATFFVPKPINLSTLPEHLTYLVRSSRVLQELHESEAQNRALLNAIPD
CCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLHVCREGTILDFRAGNGCAYAAFGGNLRGRTIADLLPPGAAAQFMAQVGHALATGTMM
HHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEE
VCEYELEGPGGLNTHEARIVANGTGTVLAIVRDVTERRQSEEMIRYLAHHDSLTGLPNRI
EEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
FFGEMLELVLSRARRDGKQVAILFVDLDDFKLINDTLGHAAGDHLLREAAQRLKGCVRSS
HHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DYVASGAESGLCGNIARFGGDEFILSLGNLDSVDDVVAVTQRIISEFSREFRIDGHEIFV
CHHHCCCCCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SVSIGISMYPDDAEDTGSLVRNADMAMFAAKEEGGPSFRFFTRGMNEAAQQRLSIELSLR
EEEECEEECCCCCHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KALERGEIFVHYQPKVDLSCGEITGFEALARWHHPELGLIPPDTFIPLAEKNGLIVRIGE
HHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEHHH
WVLRAACAQARTWIDEGFSDLCMAINLSSHQFTSGNLTSMVKEVLDETELPPSCLEFEIT
HHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEEHH
EGILMERTEKTMRILSELRDMGVRISIDDFGTGYSSLGYLKRFPVNTVKIDRSFVREIDS
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEEECHHHHHHCCC
PHEDAAIIKAIIAVARNLNLQVVAEGVESHRQTEFLLAHGCNEAQGFLFGKPVHPDEASL
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHH
MLRAGRWRDAPARALARGR
HEECCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]