Click here to switch to the map view.

The map label for this gene is tlpC [H]

Identifier: 39996136

GI number: 39996136

Start: 1113816

End: 1115417

Strand: Direct

Name: tlpC [H]

Synonym: GSU1033

Alternate gene names: 39996136

Gene position: 1113816-1115417 (Clockwise)

Preceding gene: 39996135

Following gene: 39996137

Centisome position: 29.2

GC content: 64.11

Gene sequence:

>1602_bases
ATGAAAATCAGGACCAAATTCGTAGTCGTCAATCTGTTGATCGTCTGCTGCGCCCTTGCCGCCGTGGCGGCCGCCTGCCT
CGTGGAGTTCAACCGCGAGTTGCGCCGCCAGGCCGTGACCTCCCAGGAGATCAGACTCAAGACCTTCTGGGAGCTGTTAC
GCCAGAAGGGGGACGGCTTCACCGTCGCCGACGGTAAACTGATGGCAGGCAGCTATGTCATCAACGATAATTATGAGCTT
CCCGACAAGCTGAAGGAGCTGACCGGGGGGACCGCCACCATTTTCATGGGGGATACGCGGGTCTCCACCAACGTGCTCAA
GCCGGACGGAAGCCGCGCCGTCGGAACCAAGCTGCAGGGCGCCGCCTACGACGCCGTAATAAAGGAAGGCAAACCCTACC
GGGGGGAGGCGGATATCCTCGGCGTTCCCTACTTCACCGCCTACGACCCGATCCGCGATTCCCGGGGCGAAGTAATCGGC
GTACTCTACGTGGGGGTCAAGAAAGGCGATTTCTATGCGTCCTACGAGAGTCTCAAACTGACAGTGGTCGGAATCGTGCT
GGTCATCGTGCTGCTGGCCGCCGTTGCCAGTAAGGTAATCATCCACCGGCTCTTCACCCCCCTCAATCGTATGCACGACG
TGCTGCGGGACGTGGCCCAGGGTGAGGGTGACCTGACTCAGCGGCTCGATTACCTCGCACAGGACGAGGTCGGCGACATG
AGCCGGTCGTTCAATTCATTCATGGACAAGCTCCACGGTATCATCACCCATGTTGCCCGGACCGTGGAGCAACTCGCCTC
GTCCGCGTCCCAGGTACACGGCTCTGCCGAGCAGATGGCCGCCGGCGCGGGAGAGGTGGCCTCCCAGGCGGGGACGGTGG
CCACGGCTGGCGAGGAGATGGCCGCCACGTCCACCGAGATCGCCCAGAACTGCGCCATGGCCGCCGAAGGGGCGCGCCGG
GCCAGCAGCACGGCCACTGCCGGGGCTGAGGTGGTTGGGAACACGGTAACGGTGATGGACCGGATCGCCGAAAAAGTTAA
GAACTCCGCCCGCACGGTGGAACGGCTGGGGGAGCGCAGCGACCAGATCGGAGAAATAGTCGGCACGATCGAGGATATTG
CCGATCAGACCAATCTGCTGGCGCTCAACGCTGCCATCGAGGCGGCCCGCGCCGGAGAGGCGGGGCGCGGCTTCGCCGTG
GTGGCCGACGAAGTGCGGGCCCTTGCCGAACGGACCACTAAAGCGACCCGTGAAATCTCCGGCATGATCAGGGCCATCCA
GGCGGAAACCCTGGAGGCGGTTTCCTCCATGGACGAAGGAGTCAGGGACGTGGAGACCGGCACCGCCGAAGCTGCCCGTT
CGGGGGAGGCTCTGCGGGAAATTCTCGACCAGATTACGGCGGTGTCGATGCAGGTGAACCAGATCGCCGTGGCCGCCGAG
CAGCAGACGTCCACCACCCGAGAGATCAGCGGCAACATCCAGCAGATCACCGAGGTTGTGGAGGGGACCGCCCAGGGCGC
GGACGAGTCGGCATGCGCGGCCGGCGGGCTGAATCGGCTGGCGGAGGACCTCCAGCGCATGGTGGGGCAGTTCCGGCTGT
AG

Upstream 100 bases:

>100_bases
TGGCGGTCGTGGTGCTATACTGCTGATCCCGCGTACTATTCGCGGGATGGCAGGGTGTGCACCGCACCGGCCTACTCTAC
GTGCCTCTGGAGATGCTTCC

Downstream 100 bases:

>100_bases
ATGACACTGCCGATTCCGGTTTTCATAAGAGCCCGCGCCTGTCGCGGGCTTTTTTGTAACAAATTATATTTTACCTAAAG
TCAATCAGGAAAATCCCGAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MKIRTKFVVVNLLIVCCALAAVAAACLVEFNRELRRQAVTSQEIRLKTFWELLRQKGDGFTVADGKLMAGSYVINDNYEL
PDKLKELTGGTATIFMGDTRVSTNVLKPDGSRAVGTKLQGAAYDAVIKEGKPYRGEADILGVPYFTAYDPIRDSRGEVIG
VLYVGVKKGDFYASYESLKLTVVGIVLVIVLLAAVASKVIIHRLFTPLNRMHDVLRDVAQGEGDLTQRLDYLAQDEVGDM
SRSFNSFMDKLHGIITHVARTVEQLASSASQVHGSAEQMAAGAGEVASQAGTVATAGEEMAATSTEIAQNCAMAAEGARR
ASSTATAGAEVVGNTVTVMDRIAEKVKNSARTVERLGERSDQIGEIVGTIEDIADQTNLLALNAAIEAARAGEAGRGFAV
VADEVRALAERTTKATREISGMIRAIQAETLEAVSSMDEGVRDVETGTAEAARSGEALREILDQITAVSMQVNQIAVAAE
QQTSTTREISGNIQQITEVVEGTAQGADESACAAGGLNRLAEDLQRMVGQFRL

Sequences:

>Translated_533_residues
MKIRTKFVVVNLLIVCCALAAVAAACLVEFNRELRRQAVTSQEIRLKTFWELLRQKGDGFTVADGKLMAGSYVINDNYEL
PDKLKELTGGTATIFMGDTRVSTNVLKPDGSRAVGTKLQGAAYDAVIKEGKPYRGEADILGVPYFTAYDPIRDSRGEVIG
VLYVGVKKGDFYASYESLKLTVVGIVLVIVLLAAVASKVIIHRLFTPLNRMHDVLRDVAQGEGDLTQRLDYLAQDEVGDM
SRSFNSFMDKLHGIITHVARTVEQLASSASQVHGSAEQMAAGAGEVASQAGTVATAGEEMAATSTEIAQNCAMAAEGARR
ASSTATAGAEVVGNTVTVMDRIAEKVKNSARTVERLGERSDQIGEIVGTIEDIADQTNLLALNAAIEAARAGEAGRGFAV
VADEVRALAERTTKATREISGMIRAIQAETLEAVSSMDEGVRDVETGTAEAARSGEALREILDQITAVSMQVNQIAVAAE
QQTSTTREISGNIQQITEVVEGTAQGADESACAAGGLNRLAEDLQRMVGQFRL
>Mature_533_residues
MKIRTKFVVVNLLIVCCALAAVAAACLVEFNRELRRQAVTSQEIRLKTFWELLRQKGDGFTVADGKLMAGSYVINDNYEL
PDKLKELTGGTATIFMGDTRVSTNVLKPDGSRAVGTKLQGAAYDAVIKEGKPYRGEADILGVPYFTAYDPIRDSRGEVIG
VLYVGVKKGDFYASYESLKLTVVGIVLVIVLLAAVASKVIIHRLFTPLNRMHDVLRDVAQGEGDLTQRLDYLAQDEVGDM
SRSFNSFMDKLHGIITHVARTVEQLASSASQVHGSAEQMAAGAGEVASQAGTVATAGEEMAATSTEIAQNCAMAAEGARR
ASSTATAGAEVVGNTVTVMDRIAEKVKNSARTVERLGERSDQIGEIVGTIEDIADQTNLLALNAAIEAARAGEAGRGFAV
VADEVRALAERTTKATREISGMIRAIQAETLEAVSSMDEGVRDVETGTAEAARSGEALREILDQITAVSMQVNQIAVAAE
QQTSTTREISGNIQQITEVVEGTAQGADESACAAGGLNRLAEDLQRMVGQFRL

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=314, Percent_Identity=32.1656050955414, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1787690, Length=348, Percent_Identity=30.4597701149425, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=30.2325581395349, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788194, Length=354, Percent_Identity=28.5310734463277, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789453, Length=333, Percent_Identity=30.9309309309309, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 56768; Mature: 56768

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRTKFVVVNLLIVCCALAAVAAACLVEFNRELRRQAVTSQEIRLKTFWELLRQKGDGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TVADGKLMAGSYVINDNYELPDKLKELTGGTATIFMGDTRVSTNVLKPDGSRAVGTKLQG
EEECCCEEECEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCC
AAYDAVIKEGKPYRGEADILGVPYFTAYDPIRDSRGEVIGVLYVGVKKGDFYASYESLKL
HHHHHHHHCCCCCCCCCCEECCCCHHCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHH
TVVGIVLVIVLLAAVASKVIIHRLFTPLNRMHDVLRDVAQGEGDLTQRLDYLAQDEVGDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SRSFNSFMDKLHGIITHVARTVEQLASSASQVHGSAEQMAAGAGEVASQAGTVATAGEEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCEECCHHH
AATSTEIAQNCAMAAEGARRASSTATAGAEVVGNTVTVMDRIAEKVKNSARTVERLGERS
HHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DQIGEIVGTIEDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRALAERTTKATREIS
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GMIRAIQAETLEAVSSMDEGVRDVETGTAEAARSGEALREILDQITAVSMQVNQIAVAAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
QQTSTTREISGNIQQITEVVEGTAQGADESACAAGGLNRLAEDLQRMVGQFRL
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIRTKFVVVNLLIVCCALAAVAAACLVEFNRELRRQAVTSQEIRLKTFWELLRQKGDGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TVADGKLMAGSYVINDNYELPDKLKELTGGTATIFMGDTRVSTNVLKPDGSRAVGTKLQG
EEECCCEEECEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCC
AAYDAVIKEGKPYRGEADILGVPYFTAYDPIRDSRGEVIGVLYVGVKKGDFYASYESLKL
HHHHHHHHCCCCCCCCCCEECCCCHHCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHH
TVVGIVLVIVLLAAVASKVIIHRLFTPLNRMHDVLRDVAQGEGDLTQRLDYLAQDEVGDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SRSFNSFMDKLHGIITHVARTVEQLASSASQVHGSAEQMAAGAGEVASQAGTVATAGEEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCEECCHHH
AATSTEIAQNCAMAAEGARRASSTATAGAEVVGNTVTVMDRIAEKVKNSARTVERLGERS
HHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DQIGEIVGTIEDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRALAERTTKATREIS
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GMIRAIQAETLEAVSSMDEGVRDVETGTAEAARSGEALREILDQITAVSMQVNQIAVAAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
QQTSTTREISGNIQQITEVVEGTAQGADESACAAGGLNRLAEDLQRMVGQFRL
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]