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The map label for this gene is mcp4 [H]

Identifier: 39996133

GI number: 39996133

Start: 1109751

End: 1111400

Strand: Direct

Name: mcp4 [H]

Synonym: GSU1030

Alternate gene names: 39996133

Gene position: 1109751-1111400 (Clockwise)

Preceding gene: 39996132

Following gene: 39996134

Centisome position: 29.1

GC content: 62.36

Gene sequence:

>1650_bases
ATGGCAATCAAGAGTTTCAAGGATTGGAGAATACTGCCGAAGATCATCGGCGCGGCGCTCCTCGGAGTGGCGCTCCTGGC
GGCGGTAGTGCTCTTCTACTTCCTGCCCATGGTCGAGAAGCAGGAGATGGAAAGCCGCAAGCGTGCCACCAGACAATCGG
TGGAGCTGGCCTTCGGCATCGTGGGGGCCTATGAGGCACGGATCGCGGCGGGAGAGCTGACCGTTGACGAAGCAAAGGAG
CGGGCCGCTGCTGATATCAAAAAACTGCGCTACGCCAAAAAAGAGTACTTCTGGATCAACGACTCCAGCGCGCGTCTCGT
GGCCCATCCCCTCAGGCCGGAAAACGAAGGAAAGGACATGGGGGATTTCAAGGATGCCGACGGCAAGCTGATTTACCGCG
AGTTCGCCAAGGCGGCCGGCGCAGAAAACGGCGAGTTGTTCGTGGACTACCGCCAGATCAAGCCCAACGAGAAGACGCCC
CTGCCGAAGGTTTCCTTTGTGAAGTACCACAAGCCGTGGGATTGGGTGATCGGTACCGGCATCTACGTGGACGACGTGAA
GCGGGATATCACCATGCTGCGCTGGAAGATCATCGGCGCCATCGTTGTGGCCGGCGCGGTTGCCTGTCTGCTGGTTCTCT
TTGCCGGGGTCAGGATTACCCGCCCGCTCAAGGTCGTCGTGTCGAGCCTTGAGGATATTGCCCAAGGCGAAGGGGACCTG
ACCCGGCGGATCGACGTGGTGACCCGGGATGAGGTGGGCGACCTGGGGCGTGCCTTCAACCAGTTCATCGAGAAGTTGCA
CAACATCATTTCCCAGGTTGTCCAGAACAGCATGCAGGTGGCGTCGGCCGCCGCCCAGATTCACAGCACCTCCGAGCAGA
CCGCAACGGGCGCCGAGGAGGTTGCCGCTCAGGCCGGCACCGTGGCCACGGCCGGCGAAGAAATGGCCAGCACTTCGTCG
GAGATCGCCCGCAACTGCATGGCTGCCGCCGAAAACTCGCGCCAGGCCAATGACACCGCCCTCAAGGGCTCCCATGTGGT
GAAGGAGACCCTGACGGTCATGACCCGCATCGCCGACCGGGTCAAGGAGTCCGCCCATACGGTCGAGTCCCTCGGGTCGC
GCAGCGATCAGATCGGCGAGATCGTCGGTACCATCCAGGATATTGCCGACCAGACCAACCTGCTGGCGCTTAACGCCGCC
ATCGAGGCGGCCCGGGCCGGCGAGCAGGGCCGGGGGTTCGCCGTGGTGGCCGACGAGGTGCGGGCGCTGGCGGAGCGGAC
CACCAAGGCCACCAAGGAGATCGGCCAGATGATCCGGTCGATCCAGCAGGAGACAAAGCTGGCGGTCTCTTCCATGGAGG
AAGGGGTCAAGGAAGTGGAGAGGGGAACGTCAGAGGCCGCCAAATCGGGTGAGGCGCTGGAGGAAATCCTGCACCAGATC
GGCGAGGTGACCAACCAGGTCAATCAGATCGCCACCGCCGCCGAGCAGCAGACAGCTACCACCAGCGAGATCAGCAGCAA
CATTCATGAGATCACCGAAGTTATTACCCAGACAACCCGCGGCGCCCAGGACTCAGCCTCCGCCACCAGTGACCTGGCGC
GTCTGGCCGAAGAACTTCAGCGTTTGGTGGGACAATTCCGCCTCTCCTGA

Upstream 100 bases:

>100_bases
GATCATATCAGGAAATTCCTGATAGTCCCGTCGGATTTCCTGCCGATATCAACTGATATGAAGTTTATGGGGCCTGCGGG
CCCGGAGAGCGGAGGATGCA

Downstream 100 bases:

>100_bases
AGAGTAAATGGCTCCACAGAATCCCCATTGATAAACCCGGCTCAGGCCGGGTTTATTTTTTGTGACCATTGCGAACTGCC
GATTAAAGTTTTTCGGGATT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MAIKSFKDWRILPKIIGAALLGVALLAAVVLFYFLPMVEKQEMESRKRATRQSVELAFGIVGAYEARIAAGELTVDEAKE
RAAADIKKLRYAKKEYFWINDSSARLVAHPLRPENEGKDMGDFKDADGKLIYREFAKAAGAENGELFVDYRQIKPNEKTP
LPKVSFVKYHKPWDWVIGTGIYVDDVKRDITMLRWKIIGAIVVAGAVACLLVLFAGVRITRPLKVVVSSLEDIAQGEGDL
TRRIDVVTRDEVGDLGRAFNQFIEKLHNIISQVVQNSMQVASAAAQIHSTSEQTATGAEEVAAQAGTVATAGEEMASTSS
EIARNCMAAAENSRQANDTALKGSHVVKETLTVMTRIADRVKESAHTVESLGSRSDQIGEIVGTIQDIADQTNLLALNAA
IEAARAGEQGRGFAVVADEVRALAERTTKATKEIGQMIRSIQQETKLAVSSMEEGVKEVERGTSEAAKSGEALEEILHQI
GEVTNQVNQIATAAEQQTATTSEISSNIHEITEVITQTTRGAQDSASATSDLARLAEELQRLVGQFRLS

Sequences:

>Translated_549_residues
MAIKSFKDWRILPKIIGAALLGVALLAAVVLFYFLPMVEKQEMESRKRATRQSVELAFGIVGAYEARIAAGELTVDEAKE
RAAADIKKLRYAKKEYFWINDSSARLVAHPLRPENEGKDMGDFKDADGKLIYREFAKAAGAENGELFVDYRQIKPNEKTP
LPKVSFVKYHKPWDWVIGTGIYVDDVKRDITMLRWKIIGAIVVAGAVACLLVLFAGVRITRPLKVVVSSLEDIAQGEGDL
TRRIDVVTRDEVGDLGRAFNQFIEKLHNIISQVVQNSMQVASAAAQIHSTSEQTATGAEEVAAQAGTVATAGEEMASTSS
EIARNCMAAAENSRQANDTALKGSHVVKETLTVMTRIADRVKESAHTVESLGSRSDQIGEIVGTIQDIADQTNLLALNAA
IEAARAGEQGRGFAVVADEVRALAERTTKATKEIGQMIRSIQQETKLAVSSMEEGVKEVERGTSEAAKSGEALEEILHQI
GEVTNQVNQIATAAEQQTATTSEISSNIHEITEVITQTTRGAQDSASATSDLARLAEELQRLVGQFRLS
>Mature_548_residues
AIKSFKDWRILPKIIGAALLGVALLAAVVLFYFLPMVEKQEMESRKRATRQSVELAFGIVGAYEARIAAGELTVDEAKER
AAADIKKLRYAKKEYFWINDSSARLVAHPLRPENEGKDMGDFKDADGKLIYREFAKAAGAENGELFVDYRQIKPNEKTPL
PKVSFVKYHKPWDWVIGTGIYVDDVKRDITMLRWKIIGAIVVAGAVACLLVLFAGVRITRPLKVVVSSLEDIAQGEGDLT
RRIDVVTRDEVGDLGRAFNQFIEKLHNIISQVVQNSMQVASAAAQIHSTSEQTATGAEEVAAQAGTVATAGEEMASTSSE
IARNCMAAAENSRQANDTALKGSHVVKETLTVMTRIADRVKESAHTVESLGSRSDQIGEIVGTIQDIADQTNLLALNAAI
EAARAGEQGRGFAVVADEVRALAERTTKATKEIGQMIRSIQQETKLAVSSMEEGVKEVERGTSEAAKSGEALEEILHQIG
EVTNQVNQIATAAEQQTATTSEISSNIHEITEVITQTTRGAQDSASATSDLARLAEELQRLVGQFRLS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=354, Percent_Identity=31.9209039548023, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI2367378, Length=340, Percent_Identity=30.8823529411765, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1788194, Length=352, Percent_Identity=30.9659090909091, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788195, Length=345, Percent_Identity=31.8840579710145, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789453, Length=357, Percent_Identity=28.0112044817927, Blast_Score=115, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59652; Mature: 59521

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKSFKDWRILPKIIGAALLGVALLAAVVLFYFLPMVEKQEMESRKRATRQSVELAFGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAYEARIAAGELTVDEAKERAAADIKKLRYAKKEYFWINDSSARLVAHPLRPENEGKDM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCCCCCCC
GDFKDADGKLIYREFAKAAGAENGELFVDYRQIKPNEKTPLPKVSFVKYHKPWDWVIGTG
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCHHEECC
IYVDDVKRDITMLRWKIIGAIVVAGAVACLLVLFAGVRITRPLKVVVSSLEDIAQGEGDL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCH
TRRIDVVTRDEVGDLGRAFNQFIEKLHNIISQVVQNSMQVASAAAQIHSTSEQTATGAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHH
VAAQAGTVATAGEEMASTSSEIARNCMAAAENSRQANDTALKGSHVVKETLTVMTRIADR
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHH
VKESAHTVESLGSRSDQIGEIVGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
RALAERTTKATKEIGQMIRSIQQETKLAVSSMEEGVKEVERGTSEAAKSGEALEEILHQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHH
GEVTNQVNQIATAAEQQTATTSEISSNIHEITEVITQTTRGAQDSASATSDLARLAEELQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RLVGQFRLS
HHHHHHCCC
>Mature Secondary Structure 
AIKSFKDWRILPKIIGAALLGVALLAAVVLFYFLPMVEKQEMESRKRATRQSVELAFGI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAYEARIAAGELTVDEAKERAAADIKKLRYAKKEYFWINDSSARLVAHPLRPENEGKDM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCCCCCCC
GDFKDADGKLIYREFAKAAGAENGELFVDYRQIKPNEKTPLPKVSFVKYHKPWDWVIGTG
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCHHEECC
IYVDDVKRDITMLRWKIIGAIVVAGAVACLLVLFAGVRITRPLKVVVSSLEDIAQGEGDL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCH
TRRIDVVTRDEVGDLGRAFNQFIEKLHNIISQVVQNSMQVASAAAQIHSTSEQTATGAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHH
VAAQAGTVATAGEEMASTSSEIARNCMAAAENSRQANDTALKGSHVVKETLTVMTRIADR
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHH
VKESAHTVESLGSRSDQIGEIVGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
RALAERTTKATKEIGQMIRSIQQETKLAVSSMEEGVKEVERGTSEAAKSGEALEEILHQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHH
GEVTNQVNQIATAAEQQTATTSEISSNIHEITEVITQTTRGAQDSASATSDLARLAEELQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RLVGQFRLS
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]