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The map label for this gene is sugE [H]

Identifier: 39995813

GI number: 39995813

Start: 755057

End: 755377

Strand: Reverse

Name: sugE [H]

Synonym: GSU0707

Alternate gene names: 39995813

Gene position: 755377-755057 (Counterclockwise)

Preceding gene: 39995814

Following gene: 39995812

Centisome position: 19.8

GC content: 64.17

Gene sequence:

>321_bases
ATGACGTGGGGAATTCTTGTTCTCGCAGGGCTGTTCGAGGTGGGCTGGGCCATCGGCTTGAAATTCACGGAAGGGTTCAC
CCGGCTCTGGCCGACGGTCCTGACGGTACTGGCAATGATCGCCAGTTTCTGGCTGCTGGAGATCGCCATGAGGACGCTGC
CGGTGGGCACGGCGTACAGCGTCTGGGTGGGGGTGGGTGCCGTTGGCACCGTGCTCCTGGGGATCGTGCTGTTCGGGGAA
CCGGCCAACCCGGCCCGGCTGATCAGTGTTGCGCTGATCGTCGCCGGCATCATCGGGCTCAAGCTCTCTTCGCCAGCCTG
A

Upstream 100 bases:

>100_bases
CTGCTCCACATCGGCGACGCACTGACCGACCGACGGCGGGGACGACTCCGCCGCCCGAACATCCACGGGGACGACCCCAC
GAATCGGAAAGGACGACATC

Downstream 100 bases:

>100_bases
GGACTCAGGTGACGACGCCCACCGACCGACATGCCGACCGACCCGGCACTGTCCCGGCGGCCGGCCGGCGATTCCACTAC
GCCTGGGTCATCGTGGCCGT

Product: sugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MTWGILVLAGLFEVGWAIGLKFTEGFTRLWPTVLTVLAMIASFWLLEIAMRTLPVGTAYSVWVGVGAVGTVLLGIVLFGE
PANPARLISVALIVAGIIGLKLSSPA

Sequences:

>Translated_106_residues
MTWGILVLAGLFEVGWAIGLKFTEGFTRLWPTVLTVLAMIASFWLLEIAMRTLPVGTAYSVWVGVGAVGTVLLGIVLFGE
PANPARLISVALIVAGIIGLKLSSPA
>Mature_105_residues
TWGILVLAGLFEVGWAIGLKFTEGFTRLWPTVLTVLAMIASFWLLEIAMRTLPVGTAYSVWVGVGAVGTVLLGIVLFGEP
ANPARLISVALIVAGIIGLKLSSPA

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=67.3076923076923, Blast_Score=132, Evalue=6e-33,
Organism=Escherichia coli, GI1786755, Length=85, Percent_Identity=44.7058823529412, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11153; Mature: 11021

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWGILVLAGLFEVGWAIGLKFTEGFTRLWPTVLTVLAMIASFWLLEIAMRTLPVGTAYS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VWVGVGAVGTVLLGIVLFGEPANPARLISVALIVAGIIGLKLSSPA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TWGILVLAGLFEVGWAIGLKFTEGFTRLWPTVLTVLAMIASFWLLEIAMRTLPVGTAYS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VWVGVGAVGTVLLGIVLFGEPANPARLISVALIVAGIIGLKLSSPA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA