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The map label for this gene is ycgM [C]

Identifier: 39995692

GI number: 39995692

Start: 619169

End: 619825

Strand: Reverse

Name: ycgM [C]

Synonym: GSU0585

Alternate gene names: 39995692

Gene position: 619825-619169 (Counterclockwise)

Preceding gene: 39995693

Following gene: 308513284

Centisome position: 16.25

GC content: 62.1

Gene sequence:

>657_bases
ATGAAAACCGCCAGGCTTTCCCCGTCGGGGAATGAGTTTCCCATCGGCAAGATACTCTGCATCGGCCGCAATTACGCCGA
GCACATCAAGGAGTTGGGCAACGAAACTCCCGACGCGCCGGTTGTTTTCATGAAGCCCGCCACGGCCGTCATCGGCGACG
GGGAAACCATCATCATCCCCTCCTATTCGCGCGAATGTCACCATGAGGCCGAGCTGGCGCTCCTCATCGGAAAAGGGGGG
AAAGACATCCCGCCCGAACGGGCACTGGAGCATGTGGCCGGTTACGGGGTTGCCATCGATTTGACGCTGCGGGACGTGCA
GGCCGAATTGAAGAAGAAGGGGTTGCCCTGGGAGATCGCCAAGGGATTCGACACCTCCTGCCCCCTTTCCTCTTTTGTCC
CGGCAGACCGGGTGGCCGATCCCCACGACCTGCACATTACCCTCCGGGTGAACGGAGAGATGCGCCAGGACGGCTCCTCT
TCCCTCATGATCCACCGGATTCCCCAGATCCTCAGTTACATGTCGGGAGTTTTCACCCTGGAACCGGGAGACGTGATCCT
GACCGGGACCCCCGCCGGCGTCGGCCCCCTCGCGGCGGGAGACGCCGTGGAAGCCGAGGTCGTCGGCGTGGCGGCGATCC
GGGTTACCGTTAAATAA

Upstream 100 bases:

>100_bases
CGAGCTGCGTCGGCGCGGCACCTGGCAGGGGTGCAGGCTCGACCGGGAGCACTGCCGCGTCGGCAACCTGTAGACCTCAT
CCACCCCAAGGAGGCACGAG

Downstream 100 bases:

>100_bases
TATAAATTATCATATTATTGACACTATTTTTGCACTTCCTCTCGTTAGCGAGTGAATAACTGACGGGGGTATTCTATGGA
AACACAGAAAAACTGCCCTG

Product: fumarylacetoacetate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKTARLSPSGNEFPIGKILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIPSYSRECHHEAELALLIGKGG
KDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSFVPADRVADPHDLHITLRVNGEMRQDGSS
SLMIHRIPQILSYMSGVFTLEPGDVILTGTPAGVGPLAAGDAVEAEVVGVAAIRVTVK

Sequences:

>Translated_218_residues
MKTARLSPSGNEFPIGKILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIPSYSRECHHEAELALLIGKGG
KDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSFVPADRVADPHDLHITLRVNGEMRQDGSS
SLMIHRIPQILSYMSGVFTLEPGDVILTGTPAGVGPLAAGDAVEAEVVGVAAIRVTVK
>Mature_218_residues
MKTARLSPSGNEFPIGKILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIPSYSRECHHEAELALLIGKGG
KDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSFVPADRVADPHDLHITLRVNGEMRQDGSS
SLMIHRIPQILSYMSGVFTLEPGDVILTGTPAGVGPLAAGDAVEAEVVGVAAIRVTVK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=48.5148514851485, Blast_Score=224, Evalue=4e-59,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=49.238578680203, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI66348062, Length=194, Percent_Identity=50, Blast_Score=222, Evalue=2e-58,
Organism=Homo sapiens, GI156231349, Length=199, Percent_Identity=42.2110552763819, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI40786394, Length=199, Percent_Identity=41.2060301507538, Blast_Score=160, Evalue=9e-40,
Organism=Escherichia coli, GI1787428, Length=191, Percent_Identity=52.3560209424084, Blast_Score=214, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=44.1489361702128, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=41.7777777777778, Blast_Score=175, Evalue=5e-45,
Organism=Drosophila melanogaster, GI28571789, Length=202, Percent_Identity=37.1287128712871, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28572127, Length=206, Percent_Identity=35.9223300970874, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24663695, Length=209, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23208; Mature: 23208

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTARLSPSGNEFPIGKILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIP
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEECCCEEEECCCCEEEEE
SYSRECHHEAELALLIGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIA
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCCCEEEC
KGFDTSCPLSSFVPADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTL
CCCCCCCCHHHCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEE
EPGDVILTGTPAGVGPLAAGDAVEAEVVGVAAIRVTVK
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEEEC
>Mature Secondary Structure
MKTARLSPSGNEFPIGKILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIP
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEECCCEEEECCCCEEEEE
SYSRECHHEAELALLIGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIA
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCCCEEEC
KGFDTSCPLSSFVPADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTL
CCCCCCCCHHHCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEE
EPGDVILTGTPAGVGPLAAGDAVEAEVVGVAAIRVTVK
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]