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The map label for this gene is fkpB [C]

Identifier: 39995491

GI number: 39995491

Start: 416237

End: 416665

Strand: Direct

Name: fkpB [C]

Synonym: GSU0383

Alternate gene names: 39995491

Gene position: 416237-416665 (Clockwise)

Preceding gene: 39995490

Following gene: 39995493

Centisome position: 10.91

GC content: 62.0

Gene sequence:

>429_bases
ATGGCACAGGCAAAGCAGGGGGATACCGTCACGGTTCACTATACGGGCTCGCTCACTACAGGGGAGCTTTTTGATTCGTC
GGAGGAAAGCGGTCCCCTGAAGTTCACCGTGGGCCAGGACGAGGTTATCCCGGGCTTTGAGGAGGCGGTGATCGGGATGA
GCCCCGGCGAGACAAAGACCGTAACGATTCCCGAGGACAAGGCCTATGGGGCGCGCATGCCCGAACTTGTGGCCGACGTG
GAGCGCCAGTACCTGCCGGCCGGGGCTGAGCCGGTCATCGGCCAGCAGTACGAGGTTACCCAGGATGACGGCCAGGTTTT
CAACGTGACGGTGACCGCCATGACCGACGACATGGTGACGCTGGACGCCAATCACCCGCTGGCCGGCCGTGAGCTGGTCT
TTGAAATCAAGCTGCTGGAGATCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCAACTGCCCGACTGACTTCAGAATTGCATGGATTTACGGGATTTCCGCTGGTATAGTTGCGGACGGCTGTCATCTC
ACGAGGAAAGGAACGGATAC

Downstream 100 bases:

>100_bases
TTGCGATCGGGGATGATTCCGGAATTAAAAAAGGGAAGAGGCGAGGGCCTCTTCCCTTTTTTAATACGAAGGCGTTCTAC
GCTAGTTTTCGGTCATGAAG

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAQAKQGDTVTVHYTGSLTTGELFDSSEESGPLKFTVGQDEVIPGFEEAVIGMSPGETKTVTIPEDKAYGARMPELVADV
ERQYLPAGAEPVIGQQYEVTQDDGQVFNVTVTAMTDDMVTLDANHPLAGRELVFEIKLLEIA

Sequences:

>Translated_142_residues
MAQAKQGDTVTVHYTGSLTTGELFDSSEESGPLKFTVGQDEVIPGFEEAVIGMSPGETKTVTIPEDKAYGARMPELVADV
ERQYLPAGAEPVIGQQYEVTQDDGQVFNVTVTAMTDDMVTLDANHPLAGRELVFEIKLLEIA
>Mature_141_residues
AQAKQGDTVTVHYTGSLTTGELFDSSEESGPLKFTVGQDEVIPGFEEAVIGMSPGETKTVTIPEDKAYGARMPELVADVE
RQYLPAGAEPVIGQQYEVTQDDGQVFNVTVTAMTDDMVTLDANHPLAGRELVFEIKLLEIA

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706131, Length=80, Percent_Identity=43.75, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI219842220, Length=66, Percent_Identity=45.4545454545455, Blast_Score=67, Evalue=6e-12,
Organism=Homo sapiens, GI17149836, Length=68, Percent_Identity=51.4705882352941, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI4503725, Length=68, Percent_Identity=51.4705882352941, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI4758380, Length=68, Percent_Identity=50, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1786211, Length=143, Percent_Identity=31.4685314685315, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1789748, Length=133, Percent_Identity=32.3308270676692, Blast_Score=61, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993519, Length=73, Percent_Identity=43.8356164383562, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=91, Percent_Identity=43.956043956044, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=75, Percent_Identity=44, Blast_Score=61, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24655568, Length=69, Percent_Identity=47.8260869565217, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356629, Length=65, Percent_Identity=46.1538461538462, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15307; Mature: 15176

Theoretical pI: Translated: 3.87; Mature: 3.87

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAKQGDTVTVHYTGSLTTGELFDSSEESGPLKFTVGQDEVIPGFEEAVIGMSPGETKT
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHEEEECCCCCEEE
VTIPEDKAYGARMPELVADVERQYLPAGAEPVIGQQYEVTQDDGQVFNVTVTAMTDDMVT
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCEEE
LDANHPLAGRELVFEIKLLEIA
EECCCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure 
AQAKQGDTVTVHYTGSLTTGELFDSSEESGPLKFTVGQDEVIPGFEEAVIGMSPGETKT
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHEEEECCCCCEEE
VTIPEDKAYGARMPELVADVERQYLPAGAEPVIGQQYEVTQDDGQVFNVTVTAMTDDMVT
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCEEE
LDANHPLAGRELVFEIKLLEIA
EECCCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]