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The map label for this gene is nuoE-1 [H]

Identifier: 39995451

GI number: 39995451

Start: 370496

End: 371017

Strand: Direct

Name: nuoE-1 [H]

Synonym: GSU0342

Alternate gene names: 39995451

Gene position: 370496-371017 (Clockwise)

Preceding gene: 39995450

Following gene: 39995452

Centisome position: 9.71

GC content: 54.6

Gene sequence:

>522_bases
ATGAGTAACGCTCCGGCCGAAGCTACAACCACAGAGGAAGTGCCCGTTGAGGAAATAGACCTCGGGCCAGCCAACCATGT
GATCGACAAGTACCTGACCCTGCCCGGTAACCTCATGCCGGTGCTGCAAGGCATTCAGGATGAGTATGGATACGTCCCCC
GGCCCACCATCGATTTGGTTGCCGAGAGACTCAACGTGTATCCCAGTCAGATTTTCGGCGTACTTACGTTCTATGCTCAG
TTCCACCTCAAGCCCCGCGGCCGCTTCATCATCCGGGTGTGCGTCGGAACGGCCTGTCACGTCCAGGGCGCTCCGCGAAT
CGTGGACACGTTCTTTGAGAAGTTGGGGATTGGTCACGCTGAGACAACACCCGACCTCCGCTACACATTTGAAAAGGTTG
CCTGTCTTGGTGCTTGTGGTATGGCCCCGCTGGCAATGGTTAACGATGACACGTTCGGCAAGATGACGGTACAAAAGGTC
GAAGAAATTATTGCCGAATACAATCAGAGACCGATGAAGTAA

Upstream 100 bases:

>100_bases
GGGATCGATGATTGCCGACTTGGTTGCAGTCATCGGGACCTTGGATATCGTGCTTGGTGAAATCGACCGGTAATGCCACT
GCGATAAAGGAGAGGGAGTA

Downstream 100 bases:

>100_bases
CAGACCCAACCATTCACATCAGAGGATAGAGCGTTATGGGCGAAGCGATAAAGATTCTGATCTGTCAGGGGACCGGTGGT
GTCTCAGCGGGTGCTAAAAA

Product: NADH dehydrogenase I subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSNAPAEATTTEEVPVEEIDLGPANHVIDKYLTLPGNLMPVLQGIQDEYGYVPRPTIDLVAERLNVYPSQIFGVLTFYAQ
FHLKPRGRFIIRVCVGTACHVQGAPRIVDTFFEKLGIGHAETTPDLRYTFEKVACLGACGMAPLAMVNDDTFGKMTVQKV
EEIIAEYNQRPMK

Sequences:

>Translated_173_residues
MSNAPAEATTTEEVPVEEIDLGPANHVIDKYLTLPGNLMPVLQGIQDEYGYVPRPTIDLVAERLNVYPSQIFGVLTFYAQ
FHLKPRGRFIIRVCVGTACHVQGAPRIVDTFFEKLGIGHAETTPDLRYTFEKVACLGACGMAPLAMVNDDTFGKMTVQKV
EEIIAEYNQRPMK
>Mature_172_residues
SNAPAEATTTEEVPVEEIDLGPANHVIDKYLTLPGNLMPVLQGIQDEYGYVPRPTIDLVAERLNVYPSQIFGVLTFYAQF
HLKPRGRFIIRVCVGTACHVQGAPRIVDTFFEKLGIGHAETTPDLRYTFEKVACLGACGMAPLAMVNDDTFGKMTVQKVE
EIIAEYNQRPMK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=129, Percent_Identity=39.5348837209302, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1788621, Length=143, Percent_Identity=32.1678321678322, Blast_Score=89, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561328, Length=129, Percent_Identity=39.5348837209302, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18859877, Length=131, Percent_Identity=36.6412213740458, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21355353, Length=131, Percent_Identity=32.824427480916, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19203; Mature: 19072

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAPAEATTTEEVPVEEIDLGPANHVIDKYLTLPGNLMPVLQGIQDEYGYVPRPTIDLV
CCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHH
AERLNVYPSQIFGVLTFYAQFHLKPRGRFIIRVCVGTACHVQGAPRIVDTFFEKLGIGHA
HHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHCCCCC
ETTPDLRYTFEKVACLGACGMAPLAMVNDDTFGKMTVQKVEEIIAEYNQRPMK
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNAPAEATTTEEVPVEEIDLGPANHVIDKYLTLPGNLMPVLQGIQDEYGYVPRPTIDLV
CCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHH
AERLNVYPSQIFGVLTFYAQFHLKPRGRFIIRVCVGTACHVQGAPRIVDTFFEKLGIGHA
HHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHCCCCC
ETTPDLRYTFEKVACLGACGMAPLAMVNDDTFGKMTVQKVEEIIAEYNQRPMK
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA