Click here to switch to the map view.

The map label for this gene is hypB [H]

Identifier: 39995414

GI number: 39995414

Start: 337596

End: 338360

Strand: Direct

Name: hypB [H]

Synonym: GSU0305

Alternate gene names: 39995414

Gene position: 337596-338360 (Clockwise)

Preceding gene: 39995412

Following gene: 39995415

Centisome position: 8.85

GC content: 58.69

Gene sequence:

>765_bases
ATGTGTACCACCTGCGGTTGCGAAACAGGCTCTCACCATCATCACCATGAACACGGCCATGGGCACAGTCACAGCCACGG
CCACACCCACGACGACGAGCGCGAGTCGCGAAAGATCGCGGTGGAAACCGACATCCTCTCACGTAATAATCGCTTTGCCG
CCGACAATCGGGCGCTTTTTGCGAAAAAGGGAGTGTTTGTCCTCAATCTTGTGAGTTCGCCGGGCTCCGGCAAGACAACC
ACCCTTGAGCGGACCCTTGGAGATCTGTCGGACAGGTATCGTTGCGCCGTCATCGAAGGGGATCAGCAGACCGACAACGA
CGCGCAACGCATTGCCGCTACCGGCGTGCCGGCCCGGCAGATCAACACCGGCGCCGGCTGCCATCTCGATGCCCACATGG
TTGGACATGCCGCCGAGGAGTTCGATCTGGACGCGTTGGATCTCCTTCTCGTCGAAAACGTGGGTAATTTGGTCTGCCCC
GCTTCCTTTGATCTGGGAGAGCATCACAAAGTGGTGGTCCTGTCGGTTACCGAGGGAGAGGACAAACCCCTCAAGTATCC
GAATATGTTCCACGCGGCAGACGTTATGCTGCTCAACAAGATCGACCTGCTCCCCTACGTGGATTTCGATGTCGAGAAAT
GCCTGGAGATGGCCAGGCGGGTGAGCCCTGGGATTACGATCTTTCAGGTTTCGAGCCGGACCGGCGAGGGGATGGATGCT
TGGTATGCATGGCTGGCCGACCGCATTGCGGCGGTGAAGGGGTAG

Upstream 100 bases:

>100_bases
TCAGTAGACAGAGACCATCAGGCCGTTTTCCCGGAGCGCCCCTTTTTGACCTCGGGCGCCCGTCCATATGGCCGTAATGA
AACAGGAGGCGACCAGCGTC

Downstream 100 bases:

>100_bases
GTCGGGAATTCGGCCGTGGTGCTCAGGCTCAGGATAGCCGTTGAGGGCATTGTCCAGGGCGTCGGGTTCCGCCCCTTCAT
CTTCAGGCTGGCTGCCCATC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MCTTCGCETGSHHHHHEHGHGHSHSHGHTHDDERESRKIAVETDILSRNNRFAADNRALFAKKGVFVLNLVSSPGSGKTT
TLERTLGDLSDRYRCAVIEGDQQTDNDAQRIAATGVPARQINTGAGCHLDAHMVGHAAEEFDLDALDLLLVENVGNLVCP
ASFDLGEHHKVVVLSVTEGEDKPLKYPNMFHAADVMLLNKIDLLPYVDFDVEKCLEMARRVSPGITIFQVSSRTGEGMDA
WYAWLADRIAAVKG

Sequences:

>Translated_254_residues
MCTTCGCETGSHHHHHEHGHGHSHSHGHTHDDERESRKIAVETDILSRNNRFAADNRALFAKKGVFVLNLVSSPGSGKTT
TLERTLGDLSDRYRCAVIEGDQQTDNDAQRIAATGVPARQINTGAGCHLDAHMVGHAAEEFDLDALDLLLVENVGNLVCP
ASFDLGEHHKVVVLSVTEGEDKPLKYPNMFHAADVMLLNKIDLLPYVDFDVEKCLEMARRVSPGITIFQVSSRTGEGMDA
WYAWLADRIAAVKG
>Mature_254_residues
MCTTCGCETGSHHHHHEHGHGHSHSHGHTHDDERESRKIAVETDILSRNNRFAADNRALFAKKGVFVLNLVSSPGSGKTT
TLERTLGDLSDRYRCAVIEGDQQTDNDAQRIAATGVPARQINTGAGCHLDAHMVGHAAEEFDLDALDLLLVENVGNLVCP
ASFDLGEHHKVVVLSVTEGEDKPLKYPNMFHAADVMLLNKIDLLPYVDFDVEKCLEMARRVSPGITIFQVSSRTGEGMDA
WYAWLADRIAAVKG

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=231, Percent_Identity=61.9047619047619, Blast_Score=292, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 27855; Mature: 27855

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTTCGCETGSHHHHHEHGHGHSHSHGHTHDDERESRKIAVETDILSRNNRFAADNRALF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCEEEEEEEECCCCCCCCCCCCEEE
AKKGVFVLNLVSSPGSGKTTTLERTLGDLSDRYRCAVIEGDQQTDNDAQRIAATGVPARQ
EECCEEEEEEECCCCCCCEEHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCHHH
INTGAGCHLDAHMVGHAAEEFDLDALDLLLVENVGNLVCPASFDLGEHHKVVVLSVTEGE
CCCCCCCEEEHHHHHCCHHHCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCC
DKPLKYPNMFHAADVMLLNKIDLLPYVDFDVEKCLEMARRVSPGITIFQVSSRTGEGMDA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
WYAWLADRIAAVKG
HHHHHHHHHHHCCC
>Mature Secondary Structure
MCTTCGCETGSHHHHHEHGHGHSHSHGHTHDDERESRKIAVETDILSRNNRFAADNRALF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCEEEEEEEECCCCCCCCCCCCEEE
AKKGVFVLNLVSSPGSGKTTTLERTLGDLSDRYRCAVIEGDQQTDNDAQRIAATGVPARQ
EECCEEEEEEECCCCCCCEEHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCHHH
INTGAGCHLDAHMVGHAAEEFDLDALDLLLVENVGNLVCPASFDLGEHHKVVVLSVTEGE
CCCCCCCEEEHHHHHCCHHHCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCC
DKPLKYPNMFHAADVMLLNKIDLLPYVDFDVEKCLEMARRVSPGITIFQVSSRTGEGMDA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
WYAWLADRIAAVKG
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]