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The map label for this gene is ctaD [H]

Identifier: 39995329

GI number: 39995329

Start: 227919

End: 229544

Strand: Direct

Name: ctaD [H]

Synonym: GSU0219

Alternate gene names: 39995329

Gene position: 227919-229544 (Clockwise)

Preceding gene: 39995328

Following gene: 39995330

Centisome position: 5.98

GC content: 62.79

Gene sequence:

>1626_bases
ATGAACCGGTCTGAACGGACAGGCTCCGCTGCCGGCTTCTGGAGCGATACGGAAAAGGGCGGTATCGGCGCCTGGCTTCT
CTCCACCGACCACAAACGGATCGGGCTGCTCTACTTCTGGTCGGTATTCGGCTTTTTCCTGGTGGGGGTCGTGTTGGGGC
TCATCCTCCGGCTGGAGCTGATGGCGCCGGGGCGCACCATCATGGGGCCCGATGCCTACAATGCCTTTTTCACCGTACAC
GGCGTGGTGATGATCTTTCTCTTCATCATCCCCGGCATTCCCGGCGCCTTCGGCAACATGCTGATGCCGATCCAGATCGG
GGCCCGGGACGTGGCCTTTCCCCGGTTGAATCTCCTCTCCTGGTGGCTCTATGCCACCGGCGCCGGCGTGATCCTCCTCT
CCCTCGTCACAGGCGGCGGCCCGCCGGACACCGGCTGGACCTTCTACCTCCCCTTCAGCGGCCGCACGGCCACCAACGTT
TCCCTTGCGGTTTTCGGGGTCTTCATTGTCGGATTCTCTTCCATCCTGACCGGGATCAATTTCGTAACCACCATCCACCG
GCTCCGGGCCGAGGGGATGATCTGGGGGCGGCTTCCCCTCTTTGTCTGGTCCCTCTACGCCACGGCCTGGGTCCAGATCC
TGGCCACGCCGATCCTCGGCATCACCCTGGTACTGATCATTGCCGAGCGGATCCTGGGGGTCGGCCTCTTCGATCCGAGC
CGGGGGGGGGATCCCCTCATGTACCAGCATCTCTTCTGGATTTACTCCCACCCGGCGGTTTACATCATGGTCCTGCCTGC
CATGGGAGTGGTGTCGGAGATCATCCCGGTCTTTGCCCGAAAGCCCATCTTCGGCTACAAGATGATTGCCTTCTCCAGTC
TTGCCATCGCAGCGGCCGGGTCGCTCGTCTGGGGACACCACATGTTCACCAGCGGCATGAGCGATACGGCGGTGCTGGTC
TTCTCCTTCCTCTCCTTCATCGTGGCCATACCCTCGGCCATCAAGGTCTTCAACTGGATCTCCACCCTTTATCGGGGCTC
CATCTCCCTGGATCCGCCCATGCTCTTCGCCCTCTCCTTCATCCTTCTCTTCTCCATCGGCGGGTTGACCGGCCTGATTC
TCGGTGCGGCCGCCACCGACGTCCATGTGCACGACACCCACTTCGTGGTGGGGCACTTCCACTACGTCATGTTCGGCGGC
GCCGGCTTCGCCTTCTTCGCGGCCATGCACTACTGGCTGCCCAAGTTCTACGGGCGGATGTACGCCCGCCGGCCGGCGGT
CATCGCCTGGGGGCTCATGTTCGTGGGGTTCAACATTCTCTATTTCACCATGAAGGTCCTCGGGATGAAGGGGATGCCGC
GGCGCTACTACGATTACCTTCCCGAGTTCGCGACGCTCAACCTGGTGTCTACCATCGGCAGCTGGATCCTGGCTCTGGGG
CTCGCTGTGATGCTGGTGAACCTGTTCCGGGGGCTGTGGAAGGGGGAGCCCGTGACCGAGGCGAATCCCTGGGGAGGCGC
GACCCTGGAATGGACCATCCCGACCCCGCCCCCCACGGAGAACTTTGCCGAGGAGCCGGTGGTGACCCACGGACCCTATG
ACTTCCGGGGAGCGGGGATACCATGA

Upstream 100 bases:

>100_bases
TGCGCGTGAGCGCCACGGTAGTCATCCTGACAGCCGGGGCATTTCTCGCCTTTCTGCTGACAACGGGCAGAACGGGCTCA
CGGCAGCGCAAGGGAGGATC

Downstream 100 bases:

>100_bases
GCCATGCGACCCATCGGGACTACGCCGGCGCCAAGCTCGGCATGTGGCTCTTTCTCTTCACGGAGATGCTTCTTTTCGGG
GGACTCTTCATCCTCTATGC

Product: cytochrome C oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNRSERTGSAAGFWSDTEKGGIGAWLLSTDHKRIGLLYFWSVFGFFLVGVVLGLILRLELMAPGRTIMGPDAYNAFFTVH
GVVMIFLFIIPGIPGAFGNMLMPIQIGARDVAFPRLNLLSWWLYATGAGVILLSLVTGGGPPDTGWTFYLPFSGRTATNV
SLAVFGVFIVGFSSILTGINFVTTIHRLRAEGMIWGRLPLFVWSLYATAWVQILATPILGITLVLIIAERILGVGLFDPS
RGGDPLMYQHLFWIYSHPAVYIMVLPAMGVVSEIIPVFARKPIFGYKMIAFSSLAIAAAGSLVWGHHMFTSGMSDTAVLV
FSFLSFIVAIPSAIKVFNWISTLYRGSISLDPPMLFALSFILLFSIGGLTGLILGAAATDVHVHDTHFVVGHFHYVMFGG
AGFAFFAAMHYWLPKFYGRMYARRPAVIAWGLMFVGFNILYFTMKVLGMKGMPRRYYDYLPEFATLNLVSTIGSWILALG
LAVMLVNLFRGLWKGEPVTEANPWGGATLEWTIPTPPPTENFAEEPVVTHGPYDFRGAGIP

Sequences:

>Translated_541_residues
MNRSERTGSAAGFWSDTEKGGIGAWLLSTDHKRIGLLYFWSVFGFFLVGVVLGLILRLELMAPGRTIMGPDAYNAFFTVH
GVVMIFLFIIPGIPGAFGNMLMPIQIGARDVAFPRLNLLSWWLYATGAGVILLSLVTGGGPPDTGWTFYLPFSGRTATNV
SLAVFGVFIVGFSSILTGINFVTTIHRLRAEGMIWGRLPLFVWSLYATAWVQILATPILGITLVLIIAERILGVGLFDPS
RGGDPLMYQHLFWIYSHPAVYIMVLPAMGVVSEIIPVFARKPIFGYKMIAFSSLAIAAAGSLVWGHHMFTSGMSDTAVLV
FSFLSFIVAIPSAIKVFNWISTLYRGSISLDPPMLFALSFILLFSIGGLTGLILGAAATDVHVHDTHFVVGHFHYVMFGG
AGFAFFAAMHYWLPKFYGRMYARRPAVIAWGLMFVGFNILYFTMKVLGMKGMPRRYYDYLPEFATLNLVSTIGSWILALG
LAVMLVNLFRGLWKGEPVTEANPWGGATLEWTIPTPPPTENFAEEPVVTHGPYDFRGAGIP
>Mature_541_residues
MNRSERTGSAAGFWSDTEKGGIGAWLLSTDHKRIGLLYFWSVFGFFLVGVVLGLILRLELMAPGRTIMGPDAYNAFFTVH
GVVMIFLFIIPGIPGAFGNMLMPIQIGARDVAFPRLNLLSWWLYATGAGVILLSLVTGGGPPDTGWTFYLPFSGRTATNV
SLAVFGVFIVGFSSILTGINFVTTIHRLRAEGMIWGRLPLFVWSLYATAWVQILATPILGITLVLIIAERILGVGLFDPS
RGGDPLMYQHLFWIYSHPAVYIMVLPAMGVVSEIIPVFARKPIFGYKMIAFSSLAIAAAGSLVWGHHMFTSGMSDTAVLV
FSFLSFIVAIPSAIKVFNWISTLYRGSISLDPPMLFALSFILLFSIGGLTGLILGAAATDVHVHDTHFVVGHFHYVMFGG
AGFAFFAAMHYWLPKFYGRMYARRPAVIAWGLMFVGFNILYFTMKVLGMKGMPRRYYDYLPEFATLNLVSTIGSWILALG
LAVMLVNLFRGLWKGEPVTEANPWGGATLEWTIPTPPPTENFAEEPVVTHGPYDFRGAGIP

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=509, Percent_Identity=39.6856581532416, Blast_Score=348, Evalue=8e-96,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=36.9649805447471, Blast_Score=328, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6226519, Length=532, Percent_Identity=37.218045112782, Blast_Score=364, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=37.3456790123457, Blast_Score=233, Evalue=6e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=36.2903225806452, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59436; Mature: 59436

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSERTGSAAGFWSDTEKGGIGAWLLSTDHKRIGLLYFWSVFGFFLVGVVLGLILRLEL
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAPGRTIMGPDAYNAFFTVHGVVMIFLFIIPGIPGAFGNMLMPIQIGARDVAFPRLNLLS
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
WWLYATGAGVILLSLVTGGGPPDTGWTFYLPFSGRTATNVSLAVFGVFIVGFSSILTGIN
HHHHHHCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FVTTIHRLRAEGMIWGRLPLFVWSLYATAWVQILATPILGITLVLIIAERILGVGLFDPS
HHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RGGDPLMYQHLFWIYSHPAVYIMVLPAMGVVSEIIPVFARKPIFGYKMIAFSSLAIAAAG
CCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
SLVWGHHMFTSGMSDTAVLVFSFLSFIVAIPSAIKVFNWISTLYRGSISLDPPMLFALSF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ILLFSIGGLTGLILGAAATDVHVHDTHFVVGHFHYVMFGGAGFAFFAAMHYWLPKFYGRM
HHHHHHHHHHHHHHHHHHCEEEEECCEEEHHHHEEEHCCCCHHHHHHHHHHHHHHHHHHH
YARRPAVIAWGLMFVGFNILYFTMKVLGMKGMPRRYYDYLPEFATLNLVSTIGSWILALG
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAVMLVNLFRGLWKGEPVTEANPWGGATLEWTIPTPPPTENFAEEPVVTHGPYDFRGAGI
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCC
P
C
>Mature Secondary Structure
MNRSERTGSAAGFWSDTEKGGIGAWLLSTDHKRIGLLYFWSVFGFFLVGVVLGLILRLEL
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAPGRTIMGPDAYNAFFTVHGVVMIFLFIIPGIPGAFGNMLMPIQIGARDVAFPRLNLLS
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
WWLYATGAGVILLSLVTGGGPPDTGWTFYLPFSGRTATNVSLAVFGVFIVGFSSILTGIN
HHHHHHCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FVTTIHRLRAEGMIWGRLPLFVWSLYATAWVQILATPILGITLVLIIAERILGVGLFDPS
HHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RGGDPLMYQHLFWIYSHPAVYIMVLPAMGVVSEIIPVFARKPIFGYKMIAFSSLAIAAAG
CCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
SLVWGHHMFTSGMSDTAVLVFSFLSFIVAIPSAIKVFNWISTLYRGSISLDPPMLFALSF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ILLFSIGGLTGLILGAAATDVHVHDTHFVVGHFHYVMFGGAGFAFFAAMHYWLPKFYGRM
HHHHHHHHHHHHHHHHHHCEEEEECCEEEHHHHEEEHCCCCHHHHHHHHHHHHHHHHHHH
YARRPAVIAWGLMFVGFNILYFTMKVLGMKGMPRRYYDYLPEFATLNLVSTIGSWILALG
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAVMLVNLFRGLWKGEPVTEANPWGGATLEWTIPTPPPTENFAEEPVVTHGPYDFRGAGI
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8399373 [H]