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The map label for this gene is argD [H]

Identifier: 39995262

GI number: 39995262

Start: 168667

End: 169866

Strand: Direct

Name: argD [H]

Synonym: GSU0151

Alternate gene names: 39995262

Gene position: 168667-169866 (Clockwise)

Preceding gene: 39995261

Following gene: 39995263

Centisome position: 4.42

GC content: 64.33

Gene sequence:

>1200_bases
ATGAATACCACTCAATGGATTGCAAAGGCTGACAAATACATCATGAAGACCTATGGCCGGTACCCCCTGGTGCCGGTGCG
GGGAGAAGGGTGCCGGGTCTGGGACGCGGACGGGAAGGAGTATCTGGACTTCCTTGCCGGCGTGGCCGTGAACAACCTGG
GGCACTGCCATCCGAAAGTGGTTGAGGCGCTGCGCACGCAGGCCGCCGAGATCATCCACTGCTCCAACTACTACCACATC
CCGAACCAGATCGAGCTGGCCGAGCTGCTCTGCGCCCACTCCTTCGCGGACAAGGTCTTTTTCTGCAACAGCGGCGCCGA
GGCCAACGAGGCCGCCATCAAGCTGGCCCGCAAGCATGCCCGGGAGAAGACCGGCGACGCCGAACGCTATGGCATCATCA
CGGCGCTGGCCTCCTTCCACGGCCGGACCATGGCCACCATCTCCGCCACGGGCCAGGAAAAGGTCCAGAAGTTTTTCGAC
CCGCTCCTCCACGGCTTCACCTACGTCCCCTTCGACGATGCCGCGGCCCTGGAGGCAGCGGTCACTCCCACGACCTGCGC
GGTGATGCTGGAGCCGATCCAGGGGGAAGGGGGCGTGGTCGTCCCTTCTGCCGACTACTTCCGGAAGGTTCGGGAGATCT
GCGATCGCCACGGCCTGCTCCTCATCTTCGACGAAGTTCAGGTGGGGATCGGGCGGACCGGCAAGCTCTTCGCCCATGAA
CACTTTGACGTGACCCCCGACATCATGACCCTGGCCAAGGCCCTTGCCGGGGGCGCCCCCATCGGTGCCATGCTGGCCCG
GGACGAGATCGCCGCGTCCTTTTCACCCGGCACCCACGGCTCAACCTTCGGGGGCAATCCCCTGGTCACCGCCGCGGGTT
TGGCAGCCGTCCGGGCCGTGCTGGAGGAGGGGCTCCTTAACCGGGCCGAGGAGATGGGCGAATACCTGGTGGGGGAGCTG
GAGCGGCTCAAGGGAAAATACGACATCATCACCGACGTGCGGGGCATCGGTCTCATGGTCGGCATGGAACTGTCGGTGCC
GGCCGGCGACATCGTGCTCAAGGGGCTGGAGCGGGGCGTGCTCTTGAACGTGGCCCAGGACCGGGTACTCCGGTTCGTCC
CTCCCCTGGTGGTGACCAAGCAGGAAGTGAATGACATGATCGCCGTTCTCGACGGCATCCTGGAGGAAATGACGAAATGA

Upstream 100 bases:

>100_bases
GCACCGAGATCCACCGATGACGGCCTCTCCCGGCAGGAAGCCCCGGTCAGAGGCATGAAACGGACAGGCGCGGCCCAGGC
CGCCCATGAGGATCGCTGAT

Downstream 100 bases:

>100_bases
TCAGGCACTTTCTGGCCCTCAACCAGTTTACGAAAGAGGAGCTCGACGGGCTCTTCACCCTCAGCCGGGAACTGAAGGAC
AAGCAGAAGCAGGGCGTTCC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNTTQWIAKADKYIMKTYGRYPLVPVRGEGCRVWDADGKEYLDFLAGVAVNNLGHCHPKVVEALRTQAAEIIHCSNYYHI
PNQIELAELLCAHSFADKVFFCNSGAEANEAAIKLARKHAREKTGDAERYGIITALASFHGRTMATISATGQEKVQKFFD
PLLHGFTYVPFDDAAALEAAVTPTTCAVMLEPIQGEGGVVVPSADYFRKVREICDRHGLLLIFDEVQVGIGRTGKLFAHE
HFDVTPDIMTLAKALAGGAPIGAMLARDEIAASFSPGTHGSTFGGNPLVTAAGLAAVRAVLEEGLLNRAEEMGEYLVGEL
ERLKGKYDIITDVRGIGLMVGMELSVPAGDIVLKGLERGVLLNVAQDRVLRFVPPLVVTKQEVNDMIAVLDGILEEMTK

Sequences:

>Translated_399_residues
MNTTQWIAKADKYIMKTYGRYPLVPVRGEGCRVWDADGKEYLDFLAGVAVNNLGHCHPKVVEALRTQAAEIIHCSNYYHI
PNQIELAELLCAHSFADKVFFCNSGAEANEAAIKLARKHAREKTGDAERYGIITALASFHGRTMATISATGQEKVQKFFD
PLLHGFTYVPFDDAAALEAAVTPTTCAVMLEPIQGEGGVVVPSADYFRKVREICDRHGLLLIFDEVQVGIGRTGKLFAHE
HFDVTPDIMTLAKALAGGAPIGAMLARDEIAASFSPGTHGSTFGGNPLVTAAGLAAVRAVLEEGLLNRAEEMGEYLVGEL
ERLKGKYDIITDVRGIGLMVGMELSVPAGDIVLKGLERGVLLNVAQDRVLRFVPPLVVTKQEVNDMIAVLDGILEEMTK
>Mature_399_residues
MNTTQWIAKADKYIMKTYGRYPLVPVRGEGCRVWDADGKEYLDFLAGVAVNNLGHCHPKVVEALRTQAAEIIHCSNYYHI
PNQIELAELLCAHSFADKVFFCNSGAEANEAAIKLARKHAREKTGDAERYGIITALASFHGRTMATISATGQEKVQKFFD
PLLHGFTYVPFDDAAALEAAVTPTTCAVMLEPIQGEGGVVVPSADYFRKVREICDRHGLLLIFDEVQVGIGRTGKLFAHE
HFDVTPDIMTLAKALAGGAPIGAMLARDEIAASFSPGTHGSTFGGNPLVTAAGLAAVRAVLEEGLLNRAEEMGEYLVGEL
ERLKGKYDIITDVRGIGLMVGMELSVPAGDIVLKGLERGVLLNVAQDRVLRFVPPLVVTKQEVNDMIAVLDGILEEMTK

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=37.984496124031, Blast_Score=262, Evalue=4e-70,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=39.7306397306397, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI37574042, Length=408, Percent_Identity=32.3529411764706, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=28.9592760180996, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=30.6024096385542, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=31.5104166666667, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=29.2565947242206, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI188536080, Length=418, Percent_Identity=24.8803827751196, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI38679950, Length=418, Percent_Identity=24.8803827751196, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI38679946, Length=418, Percent_Identity=24.8803827751196, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1788044, Length=377, Percent_Identity=44.8275862068966, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1789759, Length=382, Percent_Identity=43.979057591623, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI145693181, Length=372, Percent_Identity=38.1720430107527, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1789016, Length=433, Percent_Identity=33.0254041570439, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=35.25, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1786991, Length=431, Percent_Identity=30.1624129930394, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1786349, Length=326, Percent_Identity=30.9815950920245, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=388, Percent_Identity=37.8865979381443, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=32.3325635103926, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI25144274, Length=314, Percent_Identity=35.6687898089172, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71992977, Length=425, Percent_Identity=29.8823529411765, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17541228, Length=446, Percent_Identity=26.457399103139, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=174, Percent_Identity=33.9080459770115, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=36.9458128078818, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6324432, Length=399, Percent_Identity=34.3358395989975, Blast_Score=243, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6321456, Length=374, Percent_Identity=25.9358288770053, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=438, Percent_Identity=23.972602739726, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357415, Length=395, Percent_Identity=39.2405063291139, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=32.5526932084309, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=32.2429906542056, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI21356575, Length=420, Percent_Identity=32.1428571428571, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=24.1217798594848, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=24.1217798594848, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=24.1217798594848, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43252; Mature: 43252

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTQWIAKADKYIMKTYGRYPLVPVRGEGCRVWDADGKEYLDFLAGVAVNNLGHCHPKV
CCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCHHH
VEALRTQAAEIIHCSNYYHIPNQIELAELLCAHSFADKVFFCNSGAEANEAAIKLARKHA
HHHHHHHHHHHEEECCEEECCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHH
REKTGDAERYGIITALASFHGRTMATISATGQEKVQKFFDPLLHGFTYVPFDDAAALEAA
HHCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCEECCCCCHHHHHHH
VTPTTCAVMLEPIQGEGGVVVPSADYFRKVREICDRHGLLLIFDEVQVGIGRTGKLFAHE
CCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCEEEEC
HFDVTPDIMTLAKALAGGAPIGAMLARDEIAASFSPGTHGSTFGGNPLVTAAGLAAVRAV
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LEEGLLNRAEEMGEYLVGELERLKGKYDIITDVRGIGLMVGMELSVPAGDIVLKGLERGV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCC
LLNVAQDRVLRFVPPLVVTKQEVNDMIAVLDGILEEMTK
EEEHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTTQWIAKADKYIMKTYGRYPLVPVRGEGCRVWDADGKEYLDFLAGVAVNNLGHCHPKV
CCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCHHH
VEALRTQAAEIIHCSNYYHIPNQIELAELLCAHSFADKVFFCNSGAEANEAAIKLARKHA
HHHHHHHHHHHEEECCEEECCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHH
REKTGDAERYGIITALASFHGRTMATISATGQEKVQKFFDPLLHGFTYVPFDDAAALEAA
HHCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCEECCCCCHHHHHHH
VTPTTCAVMLEPIQGEGGVVVPSADYFRKVREICDRHGLLLIFDEVQVGIGRTGKLFAHE
CCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCEEEEC
HFDVTPDIMTLAKALAGGAPIGAMLARDEIAASFSPGTHGSTFGGNPLVTAAGLAAVRAV
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LEEGLLNRAEEMGEYLVGELERLKGKYDIITDVRGIGLMVGMELSVPAGDIVLKGLERGV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCC
LLNVAQDRVLRFVPPLVVTKQEVNDMIAVLDGILEEMTK
EEEHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]