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The map label for this gene is pgpA [H]

Identifier: 39995253

GI number: 39995253

Start: 157068

End: 157505

Strand: Direct

Name: pgpA [H]

Synonym: GSU0142

Alternate gene names: 39995253

Gene position: 157068-157505 (Clockwise)

Preceding gene: 39995252

Following gene: 39995254

Centisome position: 4.12

GC content: 65.07

Gene sequence:

>438_bases
GTGGTTATCGCCGCCACCTGGTTCGGCACGGGGCTGTCGCCCGTTGCCCCCGGGACGGTGGGAACCCTCGGCGCCATCCC
CCTCTACCTAGCGCTGGCGCGGCTGCCCCTCTGGCTCTATCTCGCCACTCTCGTGCCGTTCTTCTTCCTGTCGTCTTGGG
TGGCGGGACGCGCCCAGGAGGAGTTCGGTCAGAAGGACCCCGGCAAGGTGGTCATTGACGAGGTGATCGGCTATCTCATT
ACCATGGCCGGGGTGACCGCTGACTGGCGGAGTATCCTGGCCGGCTTTCTCCTCTTCCGCTTCTTCGATGTCGTGAAGAT
CTGGCCCGCCCGCTATTTCGACCGACGGATGAAAAACGGCTACGGTGTGGTGCTGGACGACGTGGCGGCCGGGCTCTATG
CCTGCGCCGCCCTCCATCTGCTGCTGGGGTACCTGTGA

Upstream 100 bases:

>100_bases
AATACGACGATTGCTGCCGGATCGCCGCCGAGCGGGGCATGCCGCTCATGGAGGTCTACCGGATCGTTGAGCGGGAGTGC
GGACAGTGACCCGACGATTC

Downstream 100 bases:

>100_bases
AGATCGCAACCCTTTCCATCGGCGACGAACTCCTGCGGGGCGAAGTGGTGGACACCAATGCCGCGCGCATCGCCGCACGC
TTGGCGGACGCGGGGCTTGC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MVIAATWFGTGLSPVAPGTVGTLGAIPLYLALARLPLWLYLATLVPFFFLSSWVAGRAQEEFGQKDPGKVVIDEVIGYLI
TMAGVTADWRSILAGFLLFRFFDVVKIWPARYFDRRMKNGYGVVLDDVAAGLYACAALHLLLGYL

Sequences:

>Translated_145_residues
MVIAATWFGTGLSPVAPGTVGTLGAIPLYLALARLPLWLYLATLVPFFFLSSWVAGRAQEEFGQKDPGKVVIDEVIGYLI
TMAGVTADWRSILAGFLLFRFFDVVKIWPARYFDRRMKNGYGVVLDDVAAGLYACAALHLLLGYL
>Mature_145_residues
MVIAATWFGTGLSPVAPGTVGTLGAIPLYLALARLPLWLYLATLVPFFFLSSWVAGRAQEEFGQKDPGKVVIDEVIGYLI
TMAGVTADWRSILAGFLLFRFFDVVKIWPARYFDRRMKNGYGVVLDDVAAGLYACAALHLLLGYL

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=135, Percent_Identity=39.2592592592593, Blast_Score=106, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 15907; Mature: 15907

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIAATWFGTGLSPVAPGTVGTLGAIPLYLALARLPLWLYLATLVPFFFLSSWVAGRAQE
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EFGQKDPGKVVIDEVIGYLITMAGVTADWRSILAGFLLFRFFDVVKIWPARYFDRRMKNG
HCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YGVVLDDVAAGLYACAALHLLLGYL
CCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIAATWFGTGLSPVAPGTVGTLGAIPLYLALARLPLWLYLATLVPFFFLSSWVAGRAQE
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EFGQKDPGKVVIDEVIGYLITMAGVTADWRSILAGFLLFRFFDVVKIWPARYFDRRMKNG
HCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YGVVLDDVAAGLYACAALHLLLGYL
CCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]