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The map label for this gene is cinA [C]

Identifier: 39995254

GI number: 39995254

Start: 157502

End: 158743

Strand: Direct

Name: cinA [C]

Synonym: GSU0143

Alternate gene names: 39995254

Gene position: 157502-158743 (Clockwise)

Preceding gene: 39995253

Following gene: 39995255

Centisome position: 4.13

GC content: 68.92

Gene sequence:

>1242_bases
GTGAAGATCGCAACCCTTTCCATCGGCGACGAACTCCTGCGGGGCGAAGTGGTGGACACCAATGCCGCGCGCATCGCCGC
ACGCTTGGCGGACGCGGGGCTTGCCGTGGGCAGGCACCTGACCGTGGGCGATGACGAGGGGGAGATCGAGGCGGCCCTCG
GCATGCTCGCTCCGGCTCATGATGCCGTCATCGTCACGGGGGGGCTCGGTCCCACGGACGACGATGTCACGGCCCGGGCC
GCGGCCCGGGCAACGGGGCGACGCCTCGTCCTGAACGAGGCGGCCCTTGACCGGCTGCGGGACTTCTTCTCCCGGCGGGG
GCGCGAGCTGTATCCCGCCAATGAGCGCCAGTGCCTCCTGCCGGCCAAGGCGGGTCTCATTCCGAACGCGCTCGGCACCG
CGTGCGGTTTCCACCTGCTGCACGGGGAATGTTTTCTGGTCTTTCTCCCCGGCGTCCCGGCCGAGATGGCCAGGATGCTG
GAAGAGTCGGTGGTGCCCCTGGTCCTTGACCGGCGGAGCGGGCCGGAGGTCACCCGAACGGCGGTACTGACGCTGTTCGG
CCTCTCCGAGGCGGAAATCGGCGGTCGACTGAGCGGACTGGAGCGTTCCCGTGGGGGGCTCGGCATTGCTTACTGCGTCG
ATTTTCCGGTAGTGCAGGTGAAACTGCGGGCCACTGCCCGAAGCGAGGAGGAGGCTGCGGAGATCATTGCCGGGGGGCTG
CCCCTGGTGCGAGAGCGCTTGGGCGATGTGATCGTGGCCGAGGGGGACAACACCATCGATACGGCGGTTGCCCGCCTGTT
TCGCGAAAAGGGGCTCACCCTCGCCCTGGCCGAGTCGTGCACCGGCGGGCTCATTGCCAAGCGGATCACCGACGTGGCTG
GCAGTTCCGCCTACTTTTTCATGGGGCTGGTCACCTATGCCAACGAGGCCAAGGAGCGACTCCTGGGCGTTCCGACCGCG
CTTCTGGCTGAAAAAGGAGCCGTGAGCGCCGATGTTGCCCGTGCCATGGCCAGGGGAGCCCGCCACGTGGCCGGCAGCGA
TCTGGCCCTGGCCGTTACCGGTATCGCCGGCCCCGATGGGGGGAGCGACGACAAGCCTGTCGGCACGGTCTACCTGGCCC
TGGCCGACCGGGCAGGCTGCTCGGTCAAGTCGTACCGCTTCGCCGGCGAGCGGGACGCCATCCGGACCGTCACGGCCGTC
ACGGCCCTGGACTGGCTGAGGAGGCGCCTCCTCACCGCCTGA

Upstream 100 bases:

>100_bases
ATTTCGACCGACGGATGAAAAACGGCTACGGTGTGGTGCTGGACGACGTGGCGGCCGGGCTCTATGCCTGCGCCGCCCTC
CATCTGCTGCTGGGGTACCT

Downstream 100 bases:

>100_bases
ATCGAAGCCGCTGTCCTTTTCTCCCGCAGCGGGAAAGCTCGTCATGTCCTTACGCAACGACAGGGTGTATCTGATTGTTG
TCAGTGTTTCGGCGCTCCTG

Product: competence/damage-inducible protein CinA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKIATLSIGDELLRGEVVDTNAARIAARLADAGLAVGRHLTVGDDEGEIEAALGMLAPAHDAVIVTGGLGPTDDDVTARA
AARATGRRLVLNEAALDRLRDFFSRRGRELYPANERQCLLPAKAGLIPNALGTACGFHLLHGECFLVFLPGVPAEMARML
EESVVPLVLDRRSGPEVTRTAVLTLFGLSEAEIGGRLSGLERSRGGLGIAYCVDFPVVQVKLRATARSEEEAAEIIAGGL
PLVRERLGDVIVAEGDNTIDTAVARLFREKGLTLALAESCTGGLIAKRITDVAGSSAYFFMGLVTYANEAKERLLGVPTA
LLAEKGAVSADVARAMARGARHVAGSDLALAVTGIAGPDGGSDDKPVGTVYLALADRAGCSVKSYRFAGERDAIRTVTAV
TALDWLRRRLLTA

Sequences:

>Translated_413_residues
MKIATLSIGDELLRGEVVDTNAARIAARLADAGLAVGRHLTVGDDEGEIEAALGMLAPAHDAVIVTGGLGPTDDDVTARA
AARATGRRLVLNEAALDRLRDFFSRRGRELYPANERQCLLPAKAGLIPNALGTACGFHLLHGECFLVFLPGVPAEMARML
EESVVPLVLDRRSGPEVTRTAVLTLFGLSEAEIGGRLSGLERSRGGLGIAYCVDFPVVQVKLRATARSEEEAAEIIAGGL
PLVRERLGDVIVAEGDNTIDTAVARLFREKGLTLALAESCTGGLIAKRITDVAGSSAYFFMGLVTYANEAKERLLGVPTA
LLAEKGAVSADVARAMARGARHVAGSDLALAVTGIAGPDGGSDDKPVGTVYLALADRAGCSVKSYRFAGERDAIRTVTAV
TALDWLRRRLLTA
>Mature_413_residues
MKIATLSIGDELLRGEVVDTNAARIAARLADAGLAVGRHLTVGDDEGEIEAALGMLAPAHDAVIVTGGLGPTDDDVTARA
AARATGRRLVLNEAALDRLRDFFSRRGRELYPANERQCLLPAKAGLIPNALGTACGFHLLHGECFLVFLPGVPAEMARML
EESVVPLVLDRRSGPEVTRTAVLTLFGLSEAEIGGRLSGLERSRGGLGIAYCVDFPVVQVKLRATARSEEEAAEIIAGGL
PLVRERLGDVIVAEGDNTIDTAVARLFREKGLTLALAESCTGGLIAKRITDVAGSSAYFFMGLVTYANEAKERLLGVPTA
LLAEKGAVSADVARAMARGARHVAGSDLALAVTGIAGPDGGSDDKPVGTVYLALADRAGCSVKSYRFAGERDAIRTVTAV
TALDWLRRRLLTA

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=413, Percent_Identity=34.1404358353511, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789052, Length=150, Percent_Identity=48.6666666666667, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787818, Length=155, Percent_Identity=30.3225806451613, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323832, Length=207, Percent_Identity=29.4685990338164, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_GEOSL (Q74GV1)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951205.1
- ProteinModelPortal:   Q74GV1
- GeneID:   2687391
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0143
- NMPDR:   fig|243231.1.peg.143
- TIGR:   GSU0143
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   CLSK827663
- BioCyc:   GSUL243231:GSU_0143-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 43318; Mature: 43318

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIATLSIGDELLRGEVVDTNAARIAARLADAGLAVGRHLTVGDDEGEIEAALGMLAPAH
CEEEEEECCHHHHCCEEECCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCC
DAVIVTGGLGPTDDDVTARAAARATGRRLVLNEAALDRLRDFFSRRGRELYPANERQCLL
CEEEEECCCCCCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCEEEC
PAKAGLIPNALGTACGFHLLHGECFLVFLPGVPAEMARMLEESVVPLVLDRRSGPEVTRT
CHHCCCCCHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCHHHH
AVLTLFGLSEAEIGGRLSGLERSRGGLGIAYCVDFPVVQVKLRATARSEEEAAEIIAGGL
HHHHHHCCCHHHCCCHHHCCHHCCCCEEEEEEECCCEEEEEEEEHHCCHHHHHHHHHCCH
PLVRERLGDVIVAEGDNTIDTAVARLFREKGLTLALAESCTGGLIAKRITDVAGSSAYFF
HHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCHHHH
MGLVTYANEAKERLLGVPTALLAEKGAVSADVARAMARGARHVAGSDLALAVTGIAGPDG
HHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCHHCCCCCEEEEEEEECCCCC
GSDDKPVGTVYLALADRAGCSVKSYRFAGERDAIRTVTAVTALDWLRRRLLTA
CCCCCCCEEEEEEEECCCCCCEEHEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIATLSIGDELLRGEVVDTNAARIAARLADAGLAVGRHLTVGDDEGEIEAALGMLAPAH
CEEEEEECCHHHHCCEEECCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCC
DAVIVTGGLGPTDDDVTARAAARATGRRLVLNEAALDRLRDFFSRRGRELYPANERQCLL
CEEEEECCCCCCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCEEEC
PAKAGLIPNALGTACGFHLLHGECFLVFLPGVPAEMARMLEESVVPLVLDRRSGPEVTRT
CHHCCCCCHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCHHHH
AVLTLFGLSEAEIGGRLSGLERSRGGLGIAYCVDFPVVQVKLRATARSEEEAAEIIAGGL
HHHHHHCCCHHHCCCHHHCCHHCCCCEEEEEEECCCEEEEEEEEHHCCHHHHHHHHHCCH
PLVRERLGDVIVAEGDNTIDTAVARLFREKGLTLALAESCTGGLIAKRITDVAGSSAYFF
HHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCHHHH
MGLVTYANEAKERLLGVPTALLAEKGAVSADVARAMARGARHVAGSDLALAVTGIAGPDG
HHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCHHCCCCCEEEEEEEECCCCC
GSDDKPVGTVYLALADRAGCSVKSYRFAGERDAIRTVTAVTALDWLRRRLLTA
CCCCCCCEEEEEEEECCCCCCEEHEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA