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The map label for this gene is capA [H]

Identifier: 39995147

GI number: 39995147

Start: 46259

End: 47314

Strand: Reverse

Name: capA [H]

Synonym: GSU0036

Alternate gene names: 39995147

Gene position: 47314-46259 (Counterclockwise)

Preceding gene: 39995155

Following gene: 39995146

Centisome position: 1.24

GC content: 63.73

Gene sequence:

>1056_bases
ATGACCATCTTCCCCGCCGCATTGACCCTAGTGCTCGTACTGCTCGCAGTCCCTGCGGGGGCTCTCGCCGAGCGCATCAG
CCTTTCTTTTGTGGGTGATGTGATGCTGGCCGGCAGCGCAACTGACACCCTCCAGCGGTACGGCTACAGCTATCCGTTTT
CCGCTACCGCCGCAGAGCTGCGACGTAGCGACCTGGTGGTGGGCAACCTGGAAGCCCCCCTCACCGACGGGGGGCGCGAG
TTCCGCGCCAAACGTTTCCGCTTCAAGGCTTCTCCCGTCGCGGCAGCGGCCCTGAAACGGGCCGGCTTCTCGGTCATGAC
ACTGGCCAATAACCACATGATGGACTTTGGCGCCGATGGGTTGAGCGACACGATTCACCATCTCAATCGTAACGGCATCG
CCTTCGCAGGCGCTGGGCCGTCAATTGCTGATGCCCGACGCGAAGCATCCGTGACGGTCAGGGGGCAGACCGTCGCCTTC
CTGGCCTACTCGCTCACCCAGCCGATCGAATTCTTCGCCACCGAGGGACGTCCTGGCACCGCACCCGGCTACGCAGGCCA
CTATCTCGCGGATATCCGACGGGTCCGCAGCAGCGCCGATCATGTGGTCGTCTCCTTCCACTGGGGACAGGAGCGCGCCG
CGCTACCATCGCCCTACCAGATCGAAACAGCCCATCGCGCTATCGATGCAGGGGCTGACATCGTCATCGGCCACCATCCC
CATGTCCTCCAGGGAATCGAAATCTATCGCGGCAGCCCGATCTTTTACAGCCTCGGTAACTTTGCCTTCGGCAGCCGGAG
CCCCTCGGCAGACCGGAGCATCATCGCCCGGGTGACCCTCGGCGAAGGACCGCCGATTGTGGAGGTCATCCCTCTCAACG
TTCTTTTCCGCGAGGTACGCTTTCAACCGGCCATCCTCACGGGCCGTAAGGCGGCGGACGTAGTGGACCGGCTGAATCGT
CTGTCAGCCCCCTTTAGCACGGTCATCACCTCCACCGCTGGCAGCCACCTCGTCGCGCCTGCGGAGGCTAATGCCCGGCT
TGCCCGCAGGCAGTGA

Upstream 100 bases:

>100_bases
GTCAAGCATTGGTTCAAGCCTTTACTTTTGCGACATGAAAGTTATAGTGTTTAGCACTAACCTGCGAATTAGTCAATATT
TTTGTGCCTCCGGAGCAGAA

Downstream 100 bases:

>100_bases
ATGGAGCAGGCTATGTATCGTCTTTTCGTTGCCATTGATCTGCCCGGTTCCGTCAGGGCACAGCTTGCCGATCTCGGCCG
GGAACTGGACGGGGTTCGCC

Product: capsule biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTIFPAALTLVLVLLAVPAGALAERISLSFVGDVMLAGSATDTLQRYGYSYPFSATAAELRRSDLVVGNLEAPLTDGGRE
FRAKRFRFKASPVAAAALKRAGFSVMTLANNHMMDFGADGLSDTIHHLNRNGIAFAGAGPSIADARREASVTVRGQTVAF
LAYSLTQPIEFFATEGRPGTAPGYAGHYLADIRRVRSSADHVVVSFHWGQERAALPSPYQIETAHRAIDAGADIVIGHHP
HVLQGIEIYRGSPIFYSLGNFAFGSRSPSADRSIIARVTLGEGPPIVEVIPLNVLFREVRFQPAILTGRKAADVVDRLNR
LSAPFSTVITSTAGSHLVAPAEANARLARRQ

Sequences:

>Translated_351_residues
MTIFPAALTLVLVLLAVPAGALAERISLSFVGDVMLAGSATDTLQRYGYSYPFSATAAELRRSDLVVGNLEAPLTDGGRE
FRAKRFRFKASPVAAAALKRAGFSVMTLANNHMMDFGADGLSDTIHHLNRNGIAFAGAGPSIADARREASVTVRGQTVAF
LAYSLTQPIEFFATEGRPGTAPGYAGHYLADIRRVRSSADHVVVSFHWGQERAALPSPYQIETAHRAIDAGADIVIGHHP
HVLQGIEIYRGSPIFYSLGNFAFGSRSPSADRSIIARVTLGEGPPIVEVIPLNVLFREVRFQPAILTGRKAADVVDRLNR
LSAPFSTVITSTAGSHLVAPAEANARLARRQ
>Mature_350_residues
TIFPAALTLVLVLLAVPAGALAERISLSFVGDVMLAGSATDTLQRYGYSYPFSATAAELRRSDLVVGNLEAPLTDGGREF
RAKRFRFKASPVAAAALKRAGFSVMTLANNHMMDFGADGLSDTIHHLNRNGIAFAGAGPSIADARREASVTVRGQTVAFL
AYSLTQPIEFFATEGRPGTAPGYAGHYLADIRRVRSSADHVVVSFHWGQERAALPSPYQIETAHRAIDAGADIVIGHHPH
VLQGIEIYRGSPIFYSLGNFAFGSRSPSADRSIIARVTLGEGPPIVEVIPLNVLFREVRFQPAILTGRKAADVVDRLNRL
SAPFSTVITSTAGSHLVAPAEANARLARRQ

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 37571; Mature: 37440

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIFPAALTLVLVLLAVPAGALAERISLSFVGDVMLAGSATDTLQRYGYSYPFSATAAEL
CEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCCHHHHHH
RRSDLVVGNLEAPLTDGGREFRAKRFRFKASPVAAAALKRAGFSVMTLANNHMMDFGADG
HHCCEEEECCCCCCCCCHHHHHHHHHEECCCHHHHHHHHHCCCEEEEEECCCEEECCCCC
LSDTIHHLNRNGIAFAGAGPSIADARREASVTVRGQTVAFLAYSLTQPIEFFATEGRPGT
HHHHHHHCCCCCEEEECCCCCHHHHHHCCEEEECCCEEEEHHHHHHCCHHEEEECCCCCC
APGYAGHYLADIRRVRSSADHVVVSFHWGQERAALPSPYQIETAHRAIDAGADIVIGHHP
CCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEHHHHHHHCCCCCEEECCCC
HVLQGIEIYRGSPIFYSLGNFAFGSRSPSADRSIIARVTLGEGPPIVEVIPLNVLFREVR
HHHCCCCEECCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHH
FQPAILTGRKAADVVDRLNRLSAPFSTVITSTAGSHLVAPAEANARLARRQ
CCCCEECCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCHHHCCC
>Mature Secondary Structure 
TIFPAALTLVLVLLAVPAGALAERISLSFVGDVMLAGSATDTLQRYGYSYPFSATAAEL
EECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCCHHHHHH
RRSDLVVGNLEAPLTDGGREFRAKRFRFKASPVAAAALKRAGFSVMTLANNHMMDFGADG
HHCCEEEECCCCCCCCCHHHHHHHHHEECCCHHHHHHHHHCCCEEEEEECCCEEECCCCC
LSDTIHHLNRNGIAFAGAGPSIADARREASVTVRGQTVAFLAYSLTQPIEFFATEGRPGT
HHHHHHHCCCCCEEEECCCCCHHHHHHCCEEEECCCEEEEHHHHHHCCHHEEEECCCCCC
APGYAGHYLADIRRVRSSADHVVVSFHWGQERAALPSPYQIETAHRAIDAGADIVIGHHP
CCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEHHHHHHHCCCCCEEECCCC
HVLQGIEIYRGSPIFYSLGNFAFGSRSPSADRSIIARVTLGEGPPIVEVIPLNVLFREVR
HHHCCCCEECCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHH
FQPAILTGRKAADVVDRLNRLSAPFSTVITSTAGSHLVAPAEANARLARRQ
CCCCEECCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]