Click here to switch to the map view.

The map label for this gene is surA [H]

Identifier: 39995126

GI number: 39995126

Start: 23311

End: 24276

Strand: Reverse

Name: surA [H]

Synonym: GSU0015

Alternate gene names: 39995126

Gene position: 24276-23311 (Counterclockwise)

Preceding gene: 39995127

Following gene: 39995124

Centisome position: 0.64

GC content: 59.94

Gene sequence:

>966_bases
ATGATCAAACGCCTCATACCTTTATCTCTTGCCGTCGTCCTCACTCTCCCGTCCCTCTCGTCCGCCGAGGTGGTAAGCCG
AATCCTCGCCGTTGTTAACGATGAGATCGTCACCTCCTACGCCGTGGACAAGGAGAAGCGGGCTCTTCTCAAGGAGGCCG
AGCGCCAGCAGCCGCCTCCCGACCCCAAGTCCCTTGCCAATCTGGACGAGGTCGCCCTCAACCGCCTCATCGACAAAAAG
CTCGTGGAACAGAAGATCCGCGAACTCGACATCCGGGTGGGTGAGGAGGAAGTACGTCAAGCAATTGAAGACGTGAAACG
GCAGAACAAGCTCTCCCAGGAGGCTCTCGTGGCGGCGTTGGCCAACCAGGGGCTTTCCTTCGACCAGTACAAGGCCCAGA
TAAAGGAACAGCTGGAGCGGCTGCGGCTCGTGAGCCAGGAGGTGCGTTCCAAGATCCAGGTGGGTGAACGGGAGATGCGG
GAGTATTACGAGGCGAACAAGGCAAAGTTCGGGGCCGAGGATATCTTCAGGGCACGGAACATCTATTTCAAGCTCGACGA
CAAGATGTCCGCCGAGCAGGTGAAAAAGGTGATGACCACGGCCATGACCGTCCTGCATGAGGCCCAGTCAGGCAAGGACT
TTGCCGAGTTGGCGCGCCAGTATTCCGACGATCCGGCGGCCAAGGGCAACGGCGGCGATCTGGGGACCTTCCGCAAGGGG
GACATCCTGCCGGAATTCGAGGAGCAGTTGACGCGGATGCAGCCGGGCGAGGTGAGCGACCTCATCTACACCGCCACAGG
GCTCCACATCGTCAAGCTGGAAGAGCGCTCCCTCGGCACCCCCAAGCCGTTCGAGCAGGTCAAGGCCGAGGTGGAAGATC
TGGTTTACCGCAAAAAATCAGAAGACCGCTTCAACCAATGGGTGGCTGACCTGCGCAAGGGAGCGGCCATCGAACTGCGG
CAGTAG

Upstream 100 bases:

>100_bases
CCGCGACACCCGCCGCCAAGTAGTGACGTAATTACCTTCAAGAGGGGGCGGGACCGCACCAGGGGTCGCCCCCTCCTCTT
TCGTGCTCAGACAACGGACC

Downstream 100 bases:

>100_bases
CCGCCCAACCGAGCAGAGCGTAAAACCCCCCCGGGGCCGCGGCTCCGGGGGGGTTTTATGCCATATCCATCTCCCTGGCG
TCGTGATTCAGATGGCACCC

Product: peptidyl-prolyl cis-trans isomerase domain-containing protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIKRLIPLSLAVVLTLPSLSSAEVVSRILAVVNDEIVTSYAVDKEKRALLKEAERQQPPPDPKSLANLDEVALNRLIDKK
LVEQKIRELDIRVGEEEVRQAIEDVKRQNKLSQEALVAALANQGLSFDQYKAQIKEQLERLRLVSQEVRSKIQVGEREMR
EYYEANKAKFGAEDIFRARNIYFKLDDKMSAEQVKKVMTTAMTVLHEAQSGKDFAELARQYSDDPAAKGNGGDLGTFRKG
DILPEFEEQLTRMQPGEVSDLIYTATGLHIVKLEERSLGTPKPFEQVKAEVEDLVYRKKSEDRFNQWVADLRKGAAIELR
Q

Sequences:

>Translated_321_residues
MIKRLIPLSLAVVLTLPSLSSAEVVSRILAVVNDEIVTSYAVDKEKRALLKEAERQQPPPDPKSLANLDEVALNRLIDKK
LVEQKIRELDIRVGEEEVRQAIEDVKRQNKLSQEALVAALANQGLSFDQYKAQIKEQLERLRLVSQEVRSKIQVGEREMR
EYYEANKAKFGAEDIFRARNIYFKLDDKMSAEQVKKVMTTAMTVLHEAQSGKDFAELARQYSDDPAAKGNGGDLGTFRKG
DILPEFEEQLTRMQPGEVSDLIYTATGLHIVKLEERSLGTPKPFEQVKAEVEDLVYRKKSEDRFNQWVADLRKGAAIELR
Q
>Mature_321_residues
MIKRLIPLSLAVVLTLPSLSSAEVVSRILAVVNDEIVTSYAVDKEKRALLKEAERQQPPPDPKSLANLDEVALNRLIDKK
LVEQKIRELDIRVGEEEVRQAIEDVKRQNKLSQEALVAALANQGLSFDQYKAQIKEQLERLRLVSQEVRSKIQVGEREMR
EYYEANKAKFGAEDIFRARNIYFKLDDKMSAEQVKKVMTTAMTVLHEAQSGKDFAELARQYSDDPAAKGNGGDLGTFRKG
DILPEFEEQLTRMQPGEVSDLIYTATGLHIVKLEERSLGTPKPFEQVKAEVEDLVYRKKSEDRFNQWVADLRKGAAIELR
Q

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=221, Percent_Identity=25.7918552036199, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1786645, Length=296, Percent_Identity=26.0135135135135, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36483; Mature: 36483

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRLIPLSLAVVLTLPSLSSAEVVSRILAVVNDEIVTSYAVDKEKRALLKEAERQQPPP
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPKSLANLDEVALNRLIDKKLVEQKIRELDIRVGEEEVRQAIEDVKRQNKLSQEALVAAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQGLSFDQYKAQIKEQLERLRLVSQEVRSKIQVGEREMREYYEANKAKFGAEDIFRARN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IYFKLDDKMSAEQVKKVMTTAMTVLHEAQSGKDFAELARQYSDDPAAKGNGGDLGTFRKG
HEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DILPEFEEQLTRMQPGEVSDLIYTATGLHIVKLEERSLGTPKPFEQVKAEVEDLVYRKKS
CCCCHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC
EDRFNQWVADLRKGAAIELRQ
HHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure
MIKRLIPLSLAVVLTLPSLSSAEVVSRILAVVNDEIVTSYAVDKEKRALLKEAERQQPPP
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPKSLANLDEVALNRLIDKKLVEQKIRELDIRVGEEEVRQAIEDVKRQNKLSQEALVAAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQGLSFDQYKAQIKEQLERLRLVSQEVRSKIQVGEREMREYYEANKAKFGAEDIFRARN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IYFKLDDKMSAEQVKKVMTTAMTVLHEAQSGKDFAELARQYSDDPAAKGNGGDLGTFRKG
HEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DILPEFEEQLTRMQPGEVSDLIYTATGLHIVKLEERSLGTPKPFEQVKAEVEDLVYRKKS
CCCCHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC
EDRFNQWVADLRKGAAIELRQ
HHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA