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The map label for this gene is yycG [H]

Identifier: 39995119

GI number: 39995119

Start: 14064

End: 15614

Strand: Direct

Name: yycG [H]

Synonym: GSU0008

Alternate gene names: 39995119

Gene position: 14064-15614 (Clockwise)

Preceding gene: 39995118

Following gene: 39995120

Centisome position: 0.37

GC content: 62.8

Gene sequence:

>1551_bases
ATGAGCGGCTACAAGGTATTCATCGTCGACGATGAAGCGGATATCGCCCTCATCCTCAAGCTGCAACTGGAGGATGCCGG
CTATCGGACCATGCGGGCGCGGGACGGGATCGAGGCCCTGGACGCTCTCGAACGGGAGAGCTTCGACCTGGTATTGCTCG
ATATCCGCATGCCGCGCATGGACGGAATCGAGGTCCTGGAGCGAATCCGGGACCGGTGGCCCGATCTGGTGGTGATCATG
ATGACCGCCCACGGGAGCGAGGACATCGCCGTAGAGGCCATGAAAAAGGGGGCGGTGGATTACATCTCCAAGCCCTTTTC
CTCCGATGATATGAAAAAGCGAGTGGAACGCGCCATCCAGTTCAACCGGACCAGACTTGAAAACGAGCGGCTGCAACGGG
TGCTCGACGAGGAACGGCGGAAGATGGGGGCGATCCTTCGGGGGATGGCGGACCTTCTCGTGGCGGTGGACCGCGAGGGA
AGGATCATCACCATCAACCGGGCAGCCGAGGAACGCTTCGGCATTGCGGCCGACGGAGTACAGAATCAGCCGGTGGAGCT
ACTCCTGAAAACAGATATCCCGGGGGAGCGCCTCCCCTGTCGCGTGGTGCTGGCCACCGGCGACCCCTGTCTTGACGTGA
CCTATGCCGTGCAGGCGGGCGGTGGCATGATCCCGGTCCTGTCCAGCGCAACTCCCCTCAAGGGCGCTGGCGGGGAAATG
ATGGGATGCGTGGAAATCATCAGGGACATCTCCACCCTCAAGGCCCTTGAACGGGAGCGCGAGGATTTCGTCTCCATGCT
CTCCCACGACTTGAAGACCCCCATCACCGCCGTGGTCGGCTCCATCGACCTGGTGCGGGAGGGGCGGATCGGCCCGGTCA
ACGCAGAGCAGCGCTCCTACCTTGATTCGGCCATGGAAAGCTGTGCCGAGATGGTGGATATGATCGACACGCTGCTCGAC
GTCCACAGGTTCGAGGCGGGGAGAATGGTCATGGCGGCCCGGCTCGAAGACCTGGGACCGCTCATGGCCCGGACCCTAGG
GCGTTTCGACTCAGTGGCCCGACGGGCGGGCATTGCCCTGGTTCTGACGCTCCCCGACTATCCTCTGGCCCTGTCGCTGG
ACCGCAACCAGTTCGCCAGGCTCATGGGCAATCTCATTGCCAATGCCATCAAGTTTACCCAAGAGGGGGGAGAGATCGAG
GTGAGCGCCCGGCTTCTGAACGACCCGGCAGAACTTGTGGGCCGCATTCCCCGGGAAAGCTATCCCGATGTGCCGTTGCC
GCCGCTGAACCCTCATCTGCTCATCACGGTGCGGGACACGGGGGTCGGCATCCCGGCCGACTCCCTCGTCAGCATCTTCG
ATCGCTTTGTCCAGGCCCGCAACCGCAGGTTGGGGAAATCGACCGGCACCGGGCTCGGCCTTGCCTTCTGCCGCAAGGTG
ATGGACGCCCACCACGGCTATATCTGGGCGGAGAGCGTCGAAGGGGAAGGCAGTTCCTTCAACATGCTGTTCCCTCTCAC
GAACGAAGCGTACGCCGCGACGGGAGGATAA

Upstream 100 bases:

>100_bases
AGGAGATCGTCGAACGGCACCACGGCAGGATTTTCTACTCTGAAGGAATCGGCGGAGGCAACGTGTTCACCTTCACCGTT
CCCATCCACGAGGGAGAGCC

Downstream 100 bases:

>100_bases
CGGCATGGGCAACGAACATCGCCGTGCTCCCCATCAAATTGCGGCCATCTACCTTGTGGTGGGGATGTTCTGGATTCTTT
TTTCCGACCGCATCCTGACG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSGYKVFIVDDEADIALILKLQLEDAGYRTMRARDGIEALDALERESFDLVLLDIRMPRMDGIEVLERIRDRWPDLVVIM
MTAHGSEDIAVEAMKKGAVDYISKPFSSDDMKKRVERAIQFNRTRLENERLQRVLDEERRKMGAILRGMADLLVAVDREG
RIITINRAAEERFGIAADGVQNQPVELLLKTDIPGERLPCRVVLATGDPCLDVTYAVQAGGGMIPVLSSATPLKGAGGEM
MGCVEIIRDISTLKALEREREDFVSMLSHDLKTPITAVVGSIDLVREGRIGPVNAEQRSYLDSAMESCAEMVDMIDTLLD
VHRFEAGRMVMAARLEDLGPLMARTLGRFDSVARRAGIALVLTLPDYPLALSLDRNQFARLMGNLIANAIKFTQEGGEIE
VSARLLNDPAELVGRIPRESYPDVPLPPLNPHLLITVRDTGVGIPADSLVSIFDRFVQARNRRLGKSTGTGLGLAFCRKV
MDAHHGYIWAESVEGEGSSFNMLFPLTNEAYAATGG

Sequences:

>Translated_516_residues
MSGYKVFIVDDEADIALILKLQLEDAGYRTMRARDGIEALDALERESFDLVLLDIRMPRMDGIEVLERIRDRWPDLVVIM
MTAHGSEDIAVEAMKKGAVDYISKPFSSDDMKKRVERAIQFNRTRLENERLQRVLDEERRKMGAILRGMADLLVAVDREG
RIITINRAAEERFGIAADGVQNQPVELLLKTDIPGERLPCRVVLATGDPCLDVTYAVQAGGGMIPVLSSATPLKGAGGEM
MGCVEIIRDISTLKALEREREDFVSMLSHDLKTPITAVVGSIDLVREGRIGPVNAEQRSYLDSAMESCAEMVDMIDTLLD
VHRFEAGRMVMAARLEDLGPLMARTLGRFDSVARRAGIALVLTLPDYPLALSLDRNQFARLMGNLIANAIKFTQEGGEIE
VSARLLNDPAELVGRIPRESYPDVPLPPLNPHLLITVRDTGVGIPADSLVSIFDRFVQARNRRLGKSTGTGLGLAFCRKV
MDAHHGYIWAESVEGEGSSFNMLFPLTNEAYAATGG
>Mature_515_residues
SGYKVFIVDDEADIALILKLQLEDAGYRTMRARDGIEALDALERESFDLVLLDIRMPRMDGIEVLERIRDRWPDLVVIMM
TAHGSEDIAVEAMKKGAVDYISKPFSSDDMKKRVERAIQFNRTRLENERLQRVLDEERRKMGAILRGMADLLVAVDREGR
IITINRAAEERFGIAADGVQNQPVELLLKTDIPGERLPCRVVLATGDPCLDVTYAVQAGGGMIPVLSSATPLKGAGGEMM
GCVEIIRDISTLKALEREREDFVSMLSHDLKTPITAVVGSIDLVREGRIGPVNAEQRSYLDSAMESCAEMVDMIDTLLDV
HRFEAGRMVMAARLEDLGPLMARTLGRFDSVARRAGIALVLTLPDYPLALSLDRNQFARLMGNLIANAIKFTQEGGEIEV
SARLLNDPAELVGRIPRESYPDVPLPPLNPHLLITVRDTGVGIPADSLVSIFDRFVQARNRRLGKSTGTGLGLAFCRKVM
DAHHGYIWAESVEGEGSSFNMLFPLTNEAYAATGG

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=275, Percent_Identity=29.0909090909091, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788549, Length=386, Percent_Identity=23.8341968911917, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=30.078125, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790299, Length=127, Percent_Identity=41.7322834645669, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=25.8687258687259, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=26.6409266409266, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=38.655462184874, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=38.1679389312977, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=26.3157894736842, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786600, Length=260, Percent_Identity=24.2307692307692, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=260, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=253, Percent_Identity=24.901185770751, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=28.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788905, Length=115, Percent_Identity=35.6521739130435, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=266, Percent_Identity=26.6917293233083, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789809, Length=114, Percent_Identity=34.2105263157895, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=30.2521008403361, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=31.3559322033898, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=264, Percent_Identity=21.969696969697, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787487, Length=142, Percent_Identity=32.3943661971831, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1786911, Length=116, Percent_Identity=33.6206896551724, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56937; Mature: 56805

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGYKVFIVDDEADIALILKLQLEDAGYRTMRARDGIEALDALERESFDLVLLDIRMPRM
CCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCC
DGIEVLERIRDRWPDLVVIMMTAHGSEDIAVEAMKKGAVDYISKPFSSDDMKKRVERAIQ
CCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHH
FNRTRLENERLQRVLDEERRKMGAILRGMADLLVAVDREGRIITINRAAEERFGIAADGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHCCCCCCCC
QNQPVELLLKTDIPGERLPCRVVLATGDPCLDVTYAVQAGGGMIPVLSSATPLKGAGGEM
CCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCCCCCHH
MGCVEIIRDISTLKALEREREDFVSMLSHDLKTPITAVVGSIDLVREGRIGPVNAEQRSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCCCCCCHHHHHH
LDSAMESCAEMVDMIDTLLDVHRFEAGRMVMAARLEDLGPLMARTLGRFDSVARRAGIAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
VLTLPDYPLALSLDRNQFARLMGNLIANAIKFTQEGGEIEVSARLLNDPAELVGRIPRES
EEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHCCCCCC
YPDVPLPPLNPHLLITVRDTGVGIPADSLVSIFDRFVQARNRRLGKSTGTGLGLAFCRKV
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
MDAHHGYIWAESVEGEGSSFNMLFPLTNEAYAATGG
HHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SGYKVFIVDDEADIALILKLQLEDAGYRTMRARDGIEALDALERESFDLVLLDIRMPRM
CCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCC
DGIEVLERIRDRWPDLVVIMMTAHGSEDIAVEAMKKGAVDYISKPFSSDDMKKRVERAIQ
CCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHH
FNRTRLENERLQRVLDEERRKMGAILRGMADLLVAVDREGRIITINRAAEERFGIAADGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHCCCCCCCC
QNQPVELLLKTDIPGERLPCRVVLATGDPCLDVTYAVQAGGGMIPVLSSATPLKGAGGEM
CCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCCCCCHH
MGCVEIIRDISTLKALEREREDFVSMLSHDLKTPITAVVGSIDLVREGRIGPVNAEQRSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCCCCCCHHHHHH
LDSAMESCAEMVDMIDTLLDVHRFEAGRMVMAARLEDLGPLMARTLGRFDSVARRAGIAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
VLTLPDYPLALSLDRNQFARLMGNLIANAIKFTQEGGEIEVSARLLNDPAELVGRIPRES
EEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHCCCCCC
YPDVPLPPLNPHLLITVRDTGVGIPADSLVSIFDRFVQARNRRLGKSTGTGLGLAFCRKV
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
MDAHHGYIWAESVEGEGSSFNMLFPLTNEAYAATGG
HHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]