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The map label for this gene is yycG [H]

Identifier: 39995118

GI number: 39995118

Start: 11779

End: 14067

Strand: Direct

Name: yycG [H]

Synonym: GSU0007

Alternate gene names: 39995118

Gene position: 11779-14067 (Clockwise)

Preceding gene: 39995117

Following gene: 39995119

Centisome position: 0.31

GC content: 60.99

Gene sequence:

>2289_bases
ATGAAATCGTTGCTCGCGATCCGCACAAAAATTTTTCTCGCCATCCTGCTCATTCTTCTCGTTTCCTATTCCTTTCTCGT
CGTTATTACCATTAGAACCGTCGATTCTTCCCTCGAGGCGGAACTGTCCCGCAAACTGGCCGAACAGGTCCGGTATGCCA
AGGACCAGTACACAAACCGGGCCGAGCAGATCCAGTACTCTCTCATGCATCCGGCCTCTGCGCCGCCCGTCCGCGAACGC
ATGGTCGCCCGCGACAGCCTCTGGCTGCGGGATGCAGCCCGCCGCTGGATGATGATCCTCCCCTTCGTGGAGTTGATCGT
GTTTGTTGATTCCCGGGGTACGGTCATCACCGGCGGGAACCAGTACCGCATGGACAGAACGTTTGAGTTGACGCCGGTCG
TGGAGCGTGCCCTCAGGGAGAGGCATCCTATCGTCTCGACTGAACTCGTGACGACCGAGTTCCTCTGCAGCGAAGGGCTG
GTTAACTACTGTCGCGGGGGAGACGCCGGGAACACGGGCGAGGTCATGATGCAGACGGTGGTGGTGCCGGTCGTGGACAC
CAGGGGGGCCATGGTCGGTGCCTTCGTGGCCGGAGACATCCTCGAAACCGACACCAGGCTCCCGTCGCAGGTTCAGGAAG
TTTTCGGCAGACAGGTGTATGTGACCATCACCCGCAAGGAGATCATCCCCCCCGACAGTTTCGGAAAAAACGGACCCCAG
GCAATTCCTGCGCGGATTCTGGGGGGCCTCAGGCAGGGGCTCCCGTTCAGGGGCGATGCGGAGATCGGCGGCAAGGTCTT
CACTGCGGCCTTCGATCCCCTTACCAATAGCAGGGGCGATTTTGTCGGAGCCCTGGTCGTGGCGCTTTCCCGCGACGACT
ACAAGGGGGTTCTGCAGGGGAGCCTGGGCAATATCGTGGCGTCGGCGATCCTGGGCCTCGTGTTGTCCTTTGTCACCGCC
TACTGGGTATCGCTCAGGCTGACGAAACCTGTTCGCGAGCTTGCGGACGGGGTTCGACGCATTGAGGAAGGGGAACTGCA
GCAGCGGGTCGCGGTCACTTCCTCCGACGAGATCGGAGAGTTGGCCGAGGCATTCAACCGGATGGCCGCAGCCATTGACG
AGCGCGACCGAACCATCCGGACCAAGGCCCACGACCTGGAGAACCTCAATCTCAAACTCACGGACATGAACGAATTCCTG
GAGCGACGGGTGGAGGAGCGGACCGCCGCATTGCAGGTGGAAATGGGACGGCTCGAGGCGATCCTTACCAGCATGGCAGA
GGGGATCGCGGTGACCGACCGGGACGGGCGCGTCATCCTGTTCAATCCGGCGGCCCAGCAGCTTTTCGAGATGGTGCCCC
ACCGCGTGGTCGGTCAGCCTATTCTGGATATCTGCAACCAGGGGGAGTTCTGCCGGCTCGTGGAGCACATCACCTCCATG
GGGGAAAACCGTGACCAGGCAACGGTCAGGGAAGTCGATCTGGACGCCCGGGGGAAAAAGCTCAAGGTCACCCTGGCGCC
CCTGGTCGATGGTGATGGGCATTTTGCCGGCGTGGTCATGTCCGTCCGCGACGTGACCGCCGAGGAGGAGGTGGACCGGA
TGAAAACCGAGTTCATTTCCACCGTCTCCCATGAACTCAAGACCCCCCTCACCTCCATCAAGGGTTCGCTCCAGCTGATC
GTGGACAAGAGCAGGGGCTTCACCGATGTGGAAAAAGAACTGCTCGGCGTATGTCTCCGCAATACCGAGCGGCTCATCCG
ACTGGTCAACGACATCCTTGATATCGCCAAGATCGAATCGGGCAAAATGGAGTTTGCCCTTTCGCCCCACTCGCCGGCTG
AGCTGGTGGAGTGGTCGGTGCGGGAGCTGGAGGGATTTGCCCGGGAGCACGGCGTAACGGTCGTCAACGAGGTGTCGGCC
GATCTGCCCGCCATATACGGCGACGGTGACCGGCTGGGGCAGGTTCTGACCAACCTCATTGCGAACGCGGTGAAATTTTC
ACCACGGGGAGCAGTGGTAACCATCTCTGCCGAGCAGAGCGACAACTTTGTCGCCGTGTCGGTCAAGGACCGCGGACGCG
AGATCCAGTGGGCCGACCGGGGGAAACTTTTCAAGAGGTTTCAGCAGATTGACAGCGGCGACCGGCGGCAGCATGGCGGC
ACCGGGCTGGGGCTTGCCATCTGTAAGGAGATCGTCGAACGGCACCACGGCAGGATTTTCTACTCTGAAGGAATCGGCGG
AGGCAACGTGTTCACCTTCACCGTTCCCATCCACGAGGGAGAGCCATGA

Upstream 100 bases:

>100_bases
TAAGAGATCATGGGGCCTCGCCGTCTCTTCACACTGAGTAGCACCGTTCGTGTATCCGTGCCCGAAAGAGACCGGAGACG
GTCTCGCTGAAGGGATTGCA

Downstream 100 bases:

>100_bases
GCGGCTACAAGGTATTCATCGTCGACGATGAAGCGGATATCGCCCTCATCCTCAAGCTGCAACTGGAGGATGCCGGCTAT
CGGACCATGCGGGCGCGGGA

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MKSLLAIRTKIFLAILLILLVSYSFLVVITIRTVDSSLEAELSRKLAEQVRYAKDQYTNRAEQIQYSLMHPASAPPVRER
MVARDSLWLRDAARRWMMILPFVELIVFVDSRGTVITGGNQYRMDRTFELTPVVERALRERHPIVSTELVTTEFLCSEGL
VNYCRGGDAGNTGEVMMQTVVVPVVDTRGAMVGAFVAGDILETDTRLPSQVQEVFGRQVYVTITRKEIIPPDSFGKNGPQ
AIPARILGGLRQGLPFRGDAEIGGKVFTAAFDPLTNSRGDFVGALVVALSRDDYKGVLQGSLGNIVASAILGLVLSFVTA
YWVSLRLTKPVRELADGVRRIEEGELQQRVAVTSSDEIGELAEAFNRMAAAIDERDRTIRTKAHDLENLNLKLTDMNEFL
ERRVEERTAALQVEMGRLEAILTSMAEGIAVTDRDGRVILFNPAAQQLFEMVPHRVVGQPILDICNQGEFCRLVEHITSM
GENRDQATVREVDLDARGKKLKVTLAPLVDGDGHFAGVVMSVRDVTAEEEVDRMKTEFISTVSHELKTPLTSIKGSLQLI
VDKSRGFTDVEKELLGVCLRNTERLIRLVNDILDIAKIESGKMEFALSPHSPAELVEWSVRELEGFAREHGVTVVNEVSA
DLPAIYGDGDRLGQVLTNLIANAVKFSPRGAVVTISAEQSDNFVAVSVKDRGREIQWADRGKLFKRFQQIDSGDRRQHGG
TGLGLAICKEIVERHHGRIFYSEGIGGGNVFTFTVPIHEGEP

Sequences:

>Translated_762_residues
MKSLLAIRTKIFLAILLILLVSYSFLVVITIRTVDSSLEAELSRKLAEQVRYAKDQYTNRAEQIQYSLMHPASAPPVRER
MVARDSLWLRDAARRWMMILPFVELIVFVDSRGTVITGGNQYRMDRTFELTPVVERALRERHPIVSTELVTTEFLCSEGL
VNYCRGGDAGNTGEVMMQTVVVPVVDTRGAMVGAFVAGDILETDTRLPSQVQEVFGRQVYVTITRKEIIPPDSFGKNGPQ
AIPARILGGLRQGLPFRGDAEIGGKVFTAAFDPLTNSRGDFVGALVVALSRDDYKGVLQGSLGNIVASAILGLVLSFVTA
YWVSLRLTKPVRELADGVRRIEEGELQQRVAVTSSDEIGELAEAFNRMAAAIDERDRTIRTKAHDLENLNLKLTDMNEFL
ERRVEERTAALQVEMGRLEAILTSMAEGIAVTDRDGRVILFNPAAQQLFEMVPHRVVGQPILDICNQGEFCRLVEHITSM
GENRDQATVREVDLDARGKKLKVTLAPLVDGDGHFAGVVMSVRDVTAEEEVDRMKTEFISTVSHELKTPLTSIKGSLQLI
VDKSRGFTDVEKELLGVCLRNTERLIRLVNDILDIAKIESGKMEFALSPHSPAELVEWSVRELEGFAREHGVTVVNEVSA
DLPAIYGDGDRLGQVLTNLIANAVKFSPRGAVVTISAEQSDNFVAVSVKDRGREIQWADRGKLFKRFQQIDSGDRRQHGG
TGLGLAICKEIVERHHGRIFYSEGIGGGNVFTFTVPIHEGEP
>Mature_762_residues
MKSLLAIRTKIFLAILLILLVSYSFLVVITIRTVDSSLEAELSRKLAEQVRYAKDQYTNRAEQIQYSLMHPASAPPVRER
MVARDSLWLRDAARRWMMILPFVELIVFVDSRGTVITGGNQYRMDRTFELTPVVERALRERHPIVSTELVTTEFLCSEGL
VNYCRGGDAGNTGEVMMQTVVVPVVDTRGAMVGAFVAGDILETDTRLPSQVQEVFGRQVYVTITRKEIIPPDSFGKNGPQ
AIPARILGGLRQGLPFRGDAEIGGKVFTAAFDPLTNSRGDFVGALVVALSRDDYKGVLQGSLGNIVASAILGLVLSFVTA
YWVSLRLTKPVRELADGVRRIEEGELQQRVAVTSSDEIGELAEAFNRMAAAIDERDRTIRTKAHDLENLNLKLTDMNEFL
ERRVEERTAALQVEMGRLEAILTSMAEGIAVTDRDGRVILFNPAAQQLFEMVPHRVVGQPILDICNQGEFCRLVEHITSM
GENRDQATVREVDLDARGKKLKVTLAPLVDGDGHFAGVVMSVRDVTAEEEVDRMKTEFISTVSHELKTPLTSIKGSLQLI
VDKSRGFTDVEKELLGVCLRNTERLIRLVNDILDIAKIESGKMEFALSPHSPAELVEWSVRELEGFAREHGVTVVNEVSA
DLPAIYGDGDRLGQVLTNLIANAVKFSPRGAVVTISAEQSDNFVAVSVKDRGREIQWADRGKLFKRFQQIDSGDRRQHGG
TGLGLAICKEIVERHHGRIFYSEGIGGGNVFTFTVPIHEGEP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=340, Percent_Identity=28.8235294117647, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=31.0344827586207, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1786600, Length=357, Percent_Identity=26.3305322128852, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788713, Length=392, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1788549, Length=350, Percent_Identity=26.8571428571429, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=31.8965517241379, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=30.7377049180328, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI48994928, Length=495, Percent_Identity=25.0505050505051, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=28.1385281385281, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=29.4930875576037, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=28.2511210762332, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=28.1124497991968, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790300, Length=362, Percent_Identity=24.8618784530387, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=25.7383966244726, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790551, Length=207, Percent_Identity=28.9855072463768, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1787374, Length=220, Percent_Identity=26.8181818181818, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=27.0742358078603, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=25.6521739130435, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84364; Mature: 84364

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLLAIRTKIFLAILLILLVSYSFLVVITIRTVDSSLEAELSRKLAEQVRYAKDQYTNR
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCH
AEQIQYSLMHPASAPPVRERMVARDSLWLRDAARRWMMILPFVELIVFVDSRGTVITGGN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCC
QYRMDRTFELTPVVERALRERHPIVSTELVTTEFLCSEGLVNYCRGGDAGNTGEVMMQTV
EEECCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VVPVVDTRGAMVGAFVAGDILETDTRLPSQVQEVFGRQVYVTITRKEIIPPDSFGKNGPQ
HEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCC
AIPARILGGLRQGLPFRGDAEIGGKVFTAAFDPLTNSRGDFVGALVVALSRDDYKGVLQG
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHC
SLGNIVASAILGLVLSFVTAYWVSLRLTKPVRELADGVRRIEEGELQQRVAVTSSDEIGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LAEAFNRMAAAIDERDRTIRTKAHDLENLNLKLTDMNEFLERRVEERTAALQVEMGRLEA
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ILTSMAEGIAVTDRDGRVILFNPAAQQLFEMVPHRVVGQPILDICNQGEFCRLVEHITSM
HHHHHHCCCEEECCCCEEEEECHHHHHHHHHCCHHHCCCHHHHHHCCCCHHHHHHHHHHC
GENRDQATVREVDLDARGKKLKVTLAPLVDGDGHFAGVVMSVRDVTAEEEVDRMKTEFIS
CCCCCCCHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSHELKTPLTSIKGSLQLIVDKSRGFTDVEKELLGVCLRNTERLIRLVNDILDIAKIES
HHHHHHHCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKMEFALSPHSPAELVEWSVRELEGFAREHGVTVVNEVSADLPAIYGDGDRLGQVLTNLI
CCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCCEEECCHHHHHHHHHHHH
ANAVKFSPRGAVVTISAEQSDNFVAVSVKDRGREIQWADRGKLFKRFQQIDSGDRRQHGG
HHHHEECCCCEEEEEEECCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHCCCCCCCCCC
TGLGLAICKEIVERHHGRIFYSEGIGGGNVFTFTVPIHEGEP
CCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MKSLLAIRTKIFLAILLILLVSYSFLVVITIRTVDSSLEAELSRKLAEQVRYAKDQYTNR
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCH
AEQIQYSLMHPASAPPVRERMVARDSLWLRDAARRWMMILPFVELIVFVDSRGTVITGGN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCC
QYRMDRTFELTPVVERALRERHPIVSTELVTTEFLCSEGLVNYCRGGDAGNTGEVMMQTV
EEECCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VVPVVDTRGAMVGAFVAGDILETDTRLPSQVQEVFGRQVYVTITRKEIIPPDSFGKNGPQ
HEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCC
AIPARILGGLRQGLPFRGDAEIGGKVFTAAFDPLTNSRGDFVGALVVALSRDDYKGVLQG
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHC
SLGNIVASAILGLVLSFVTAYWVSLRLTKPVRELADGVRRIEEGELQQRVAVTSSDEIGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LAEAFNRMAAAIDERDRTIRTKAHDLENLNLKLTDMNEFLERRVEERTAALQVEMGRLEA
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ILTSMAEGIAVTDRDGRVILFNPAAQQLFEMVPHRVVGQPILDICNQGEFCRLVEHITSM
HHHHHHCCCEEECCCCEEEEECHHHHHHHHHCCHHHCCCHHHHHHCCCCHHHHHHHHHHC
GENRDQATVREVDLDARGKKLKVTLAPLVDGDGHFAGVVMSVRDVTAEEEVDRMKTEFIS
CCCCCCCHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSHELKTPLTSIKGSLQLIVDKSRGFTDVEKELLGVCLRNTERLIRLVNDILDIAKIES
HHHHHHHCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKMEFALSPHSPAELVEWSVRELEGFAREHGVTVVNEVSADLPAIYGDGDRLGQVLTNLI
CCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCCEEECCHHHHHHHHHHHH
ANAVKFSPRGAVVTISAEQSDNFVAVSVKDRGREIQWADRGKLFKRFQQIDSGDRRQHGG
HHHHEECCCCEEEEEEECCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHCCCCCCCCCC
TGLGLAICKEIVERHHGRIFYSEGIGGGNVFTFTVPIHEGEP
CCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]