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The map label for this gene is accA

Identifier: 308513299

GI number: 308513299

Start: 1543895

End: 1544836

Strand: Direct

Name: accA

Synonym: NA

Alternate gene names: 308513299

Gene position: 1543895-1544836 (Clockwise)

Preceding gene: 39996502

Following gene: 39996504

Centisome position: 40.48

GC content: 64.97

Gene sequence:

>942_bases
ATGGAATTCGAAAAACCGGTGGTTGAGCTTGAGAAAAAAGTACAGGAACTGGCCGAACTGGCCGGCACTAACGCCGAACT
GGCGGGCGAAGTGACCAAGCTGGAGAAGAAGGTCGACCGGATGCGCGAGGTGATCTTCTCCAACCTGTCCCGCTGGCAGA
CGGTGCAGGTGGCCCGCCACATCGAGCGTCCCTTCACCCTGGACTACCTCAACCTGATCTTCACCGATTTCACCGAACTC
CATGGCGACCGCCTGTTCGGCGACGATCACGCCATTGTCGCCGGCCTGGCGAAGCTCGACGGTGAGCCGGTGGTGGTCAT
CGGCCACCAGAAGGGGCGCGACACCAAGGAGAAGGTCTACCGCAACTTCGGCATGCCCAACCCCGAGGGGTACCGCAAGG
CCCTGCGGATCATGGAGCTGGCCGAGCGGTTCCGGCTGCCCATCATCACCTTCGTGGACACCCCCGGCGCGTTTCCCGGC
ATCGGCGCCGAGGAGCGGGGCCAGGCCGAGGCCATTGCGCGCAACCTCAGGGAGATGGCGGCCCTCACCGTGCCGATCAT
TGTCGTGGTCACCGGAGAGGGGGGCTCCGGCGGGGCGCTGGCCATCGCCGTGGGCGACCGGGTCCTCATGCTCCAGTACT
CCATCTACGCCGTCATCTCCCCCGAGGGGTGCGCCGCCATCCTCTGGTCCGACGGCACTAAGGGTGAGCAGGCCGCCGAG
GCCCTCAAACTGACCGCCAAGGACCTGAAGGAGCTTGAGGTGATCGACGAGATTGTGCCCGAGCCCCTGGGCGGCGCCCA
CCGCGACCATGAGGCCATGGCCAGGACCCTCCACGAAGCCATCGCCCGGCAGTTGAAGGAGCTGAAGGCGATTCCCGCGG
AGCAACTGGTGGAGGAGCGGTACCAGAAGTTCCGCAAAATGTCGCGCTTCATCGAAGGGTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:
NA

Sequences:

>Translated_313_residues
MEFEKPVVELEKKVQELAELAGTNAELAGEVTKLEKKVDRMREVIFSNLSRWQTVQVARHIERPFTLDYLNLIFTDFTEL
HGDRLFGDDHAIVAGLAKLDGEPVVVIGHQKGRDTKEKVYRNFGMPNPEGYRKALRIMELAERFRLPIITFVDTPGAFPG
IGAEERGQAEAIARNLREMAALTVPIIVVVTGEGGSGGALAIAVGDRVLMLQYSIYAVISPEGCAAILWSDGTKGEQAAE
ALKLTAKDLKELEVIDEIVPEPLGGAHRDHEAMARTLHEAIARQLKELKAIPAEQLVEERYQKFRKMSRFIEG
>Mature_313_residues
MEFEKPVVELEKKVQELAELAGTNAELAGEVTKLEKKVDRMREVIFSNLSRWQTVQVARHIERPFTLDYLNLIFTDFTEL
HGDRLFGDDHAIVAGLAKLDGEPVVVIGHQKGRDTKEKVYRNFGMPNPEGYRKALRIMELAERFRLPIITFVDTPGAFPG
IGAEERGQAEAIARNLREMAALTVPIIVVVTGEGGSGGALAIAVGDRVLMLQYSIYAVISPEGCAAILWSDGTKGEQAAE
ALKLTAKDLKELEVIDEIVPEPLGGAHRDHEAMARTLHEAIARQLKELKAIPAEQLVEERYQKFRKMSRFIEG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=308, Percent_Identity=57.7922077922078, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_GEOSL (Q74DB5)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952454.3
- ProteinModelPortal:   Q74DB5
- SMR:   Q74DB5
- GeneID:   2687857
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1402
- NMPDR:   fig|243231.1.peg.1392
- TIGR:   GSU1402
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   GSUL243231:GSU_1402-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34797; Mature: 34797

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEKPVVELEKKVQELAELAGTNAELAGEVTKLEKKVDRMREVIFSNLSRWQTVQVARH
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERPFTLDYLNLIFTDFTELHGDRLFGDDHAIVAGLAKLDGEPVVVIGHQKGRDTKEKVY
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
RNFGMPNPEGYRKALRIMELAERFRLPIITFVDTPGAFPGIGAEERGQAEAIARNLREMA
HHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
ALTVPIIVVVTGEGGSGGALAIAVGDRVLMLQYSIYAVISPEGCAAILWSDGTKGEQAAE
HHHEEEEEEEECCCCCCCEEEEEECCEEEEEEEEEEEEECCCCCEEEEECCCCCHHHHHH
ALKLTAKDLKELEVIDEIVPEPLGGAHRDHEAMARTLHEAIARQLKELKAIPAEQLVEER
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YQKFRKMSRFIEG
HHHHHHHHHHHCC
>Mature Secondary Structure
MEFEKPVVELEKKVQELAELAGTNAELAGEVTKLEKKVDRMREVIFSNLSRWQTVQVARH
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERPFTLDYLNLIFTDFTELHGDRLFGDDHAIVAGLAKLDGEPVVVIGHQKGRDTKEKVY
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
RNFGMPNPEGYRKALRIMELAERFRLPIITFVDTPGAFPGIGAEERGQAEAIARNLREMA
HHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
ALTVPIIVVVTGEGGSGGALAIAVGDRVLMLQYSIYAVISPEGCAAILWSDGTKGEQAAE
HHHEEEEEEEECCCCCCCEEEEEECCEEEEEEEEEEEEECCCCCEEEEECCCCCHHHHHH
ALKLTAKDLKELEVIDEIVPEPLGGAHRDHEAMARTLHEAIARQLKELKAIPAEQLVEER
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YQKFRKMSRFIEG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA