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The map label for this gene is yycF [H]

Identifier: 57234839

GI number: 57234839

Start: 303681

End: 304358

Strand: Direct

Name: yycF [H]

Synonym: DET0316

Alternate gene names: 57234839

Gene position: 303681-304358 (Clockwise)

Preceding gene: 57234840

Following gene: 57234837

Centisome position: 20.66

GC content: 43.51

Gene sequence:

>678_bases
ATGAAGACCCTGATAATAGAGGATGATTTATCCATAATTGATCTGGTAGTGCTTACCCTTTCGGTAGCCTGGCCAGATAT
CCAGATAGTTAGAACCCAGCTTGGCAAAGAGGGCATAGAGCTAGCTGAAACCGAAGCGCCAGATTTTATTATACTTGACC
TTGGTCTGCCGGATATGAGCGGTATAGAAGTACTTCAGGAAATACGCAGTTTTTCCAAGGTGCCCGTTTTAGTGCTGACT
GTAAAAAAAGATGAGATGGATGTGGTAGTGGCACTCAGCAAGGGAGCTGACGAGTTTATCAGCAAACCTTTCCGCCAAAT
GGAACTAATCTCCAGGGTAAAAAATGTCTTAAAGCGGTCACATCCTTCGGAGGGTGAAGTATACGCTATAGGTAACCTGA
CCTACTATCCCGCCCTGAACAAAATAGATTCTAAAGGTCTTGAACTTAAGCTTTCACCTACTGAAAATATCATCTTCCTT
TATCTGGCTAATCAGCGGCCGAATTATGTTACCTACCGAAGCCTTGCCTTGGCCATCTGGGGTGATGAATATCCGGGTTG
CCATAAAGCAATACGGGTGATGGTTAATCAGTTGAGAGAGAAGCTTGATTCATCATTGAACCAGCCTGATTTGATACTGA
CTAAGTATGGTTTGGGTTATTATCTTGGCAACTGGTAA

Upstream 100 bases:

>100_bases
AAGATGATTATTGAACTGCACAGGGGTGAGATATGGTTTACCAGTGAATACGGCCATGGCAGTACCTTTTACTTTACACT
ACCGATAAGGAGCGAATGGG

Downstream 100 bases:

>100_bases
ATACCCGTGTTAGCCTCCTTTTTCAGAAAAATCCTTCGTTTTTATGCTTTATGCTCGGTTTCCCCTCTTCATAAGTAAAC
TCTAATGCGTTTATAAGAAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTLIIEDDLSIIDLVVLTLSVAWPDIQIVRTQLGKEGIELAETEAPDFIILDLGLPDMSGIEVLQEIRSFSKVPVLVLT
VKKDEMDVVVALSKGADEFISKPFRQMELISRVKNVLKRSHPSEGEVYAIGNLTYYPALNKIDSKGLELKLSPTENIIFL
YLANQRPNYVTYRSLALAIWGDEYPGCHKAIRVMVNQLREKLDSSLNQPDLILTKYGLGYYLGNW

Sequences:

>Translated_225_residues
MKTLIIEDDLSIIDLVVLTLSVAWPDIQIVRTQLGKEGIELAETEAPDFIILDLGLPDMSGIEVLQEIRSFSKVPVLVLT
VKKDEMDVVVALSKGADEFISKPFRQMELISRVKNVLKRSHPSEGEVYAIGNLTYYPALNKIDSKGLELKLSPTENIIFL
YLANQRPNYVTYRSLALAIWGDEYPGCHKAIRVMVNQLREKLDSSLNQPDLILTKYGLGYYLGNW
>Mature_225_residues
MKTLIIEDDLSIIDLVVLTLSVAWPDIQIVRTQLGKEGIELAETEAPDFIILDLGLPDMSGIEVLQEIRSFSKVPVLVLT
VKKDEMDVVVALSKGADEFISKPFRQMELISRVKNVLKRSHPSEGEVYAIGNLTYYPALNKIDSKGLELKLSPTENIIFL
YLANQRPNYVTYRSLALAIWGDEYPGCHKAIRVMVNQLREKLDSSLNQPDLILTKYGLGYYLGNW

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=31.9634703196347, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=30.4545454545455, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=33.1896551724138, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=28.0542986425339, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=29.7777777777778, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=26.431718061674, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=29.9107142857143, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=27.3127753303965, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI2367329, Length=175, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787229, Length=195, Percent_Identity=27.1794871794872, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=29.7777777777778, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.2511210762332, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790863, Length=184, Percent_Identity=27.1739130434783, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=24.8945147679325, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25384; Mature: 25384

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLIIEDDLSIIDLVVLTLSVAWPDIQIVRTQLGKEGIELAETEAPDFIILDLGLPDMS
CCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEHHCCCCCEEEEEECCCCCH
GIEVLQEIRSFSKVPVLVLTVKKDEMDVVVALSKGADEFISKPFRQMELISRVKNVLKRS
HHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHHC
HPSEGEVYAIGNLTYYPALNKIDSKGLELKLSPTENIIFLYLANQRPNYVTYRSLALAIW
CCCCCCEEEECCEEECCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEEEEEEEE
GDEYPGCHKAIRVMVNQLREKLDSSLNQPDLILTKYGLGYYLGNW
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCC
>Mature Secondary Structure
MKTLIIEDDLSIIDLVVLTLSVAWPDIQIVRTQLGKEGIELAETEAPDFIILDLGLPDMS
CCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEHHCCCCCEEEEEECCCCCH
GIEVLQEIRSFSKVPVLVLTVKKDEMDVVVALSKGADEFISKPFRQMELISRVKNVLKRS
HHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHHC
HPSEGEVYAIGNLTYYPALNKIDSKGLELKLSPTENIIFLYLANQRPNYVTYRSLALAIW
CCCCCCEEEECCEEECCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEEEEEEEE
GDEYPGCHKAIRVMVNQLREKLDSSLNQPDLILTKYGLGYYLGNW
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]