Click here to switch to the map view.

The map label for this gene is arcB [H]

Identifier: 57234840

GI number: 57234840

Start: 302102

End: 303706

Strand: Direct

Name: arcB [H]

Synonym: DET0315

Alternate gene names: 57234840

Gene position: 302102-303706 (Clockwise)

Preceding gene: 57234841

Following gene: 57234839

Centisome position: 20.56

GC content: 43.61

Gene sequence:

>1605_bases
ATGATTGATAACTTGGATACGATTCAGATCGATACCTTGCCTGTAGGTATTGTAGTGATAGATGTTTTGTCCAGAAAAAT
CATGAATATAAATCAGGCGGCCCAGAATCTTATCGGGGCAGAGGCATCCGAGATTATAGGCCATTCCTGCCATAAGTTCA
TTTGCCCGGCGGAAGAGGGTAAATGCCCGATACTTGATATGGGGCAATCAATAGACAATGCTGAAAGGCAGCTGCTGACC
AGCAGTAGCAAGCTGATTACTATTTTAAAAACTGCAAGCAAGGTTACCATAAATGGCAGGGATTTTCTGTATGAAGTCCT
TCAGGATGTGACTGACCCGGTTAATCTCCGTAAACAGCTTCAGATACAGGTGGCGGAGCGTACCAAAGAGCTGGCCGAAA
TAAACAGCAAACTCGTTCAGGAGATAAAAAACCATGAGAAAACCGAACGTAAATTAAACGAACTGTTTACCCGTTATTCA
ATGTTTTTCAACAACTGCAATGACGGGTTAACTTTGATTGATTTTTCAGGTGGAACACCGCCCGGTAAATATATTGAAGT
AAACAAGGCGTTTTGCCAGATGGTTAATTATTCACGGGAAGAGCTTCTTCAGTTGACCCCGATTGACCTTACCGCTTCGG
AGATGAAAGATTATGCGCTGGGAAATACAAAACTGGTGTTGGAGTCTGAATATGCGGTACTCCGTTTCCCGAATGTATAT
ATTACCAAAGATGGCAGGCGGCTGGATTGCGAAATAAATGCCAGTTTTGTTTATTTATCTGGACGGGAAGTGGCGGTAGT
AGTATATCGGGATATTTCGGAAACCAAGCGCTTGGAACAAAGTCTTCGTGAAGCCTATGAGCGGGAACTTCAGGCCCATG
CGGAGGTTGAAGATCAGCTAAACCAGCGCAATTATTTTATGCGGGCACTGGTGCATGAGCTTAAAACATCTCTTACTCCG
CTGCTTGCCGCTAGTGAGTATTTGGTATCTGAACTTTCGGACAGTGCTTTATTAGGTTATGCACGAAACATGCAGAATGG
GGCTATTAATCTGAATAACAAGATTGATGACCTTATGAACTTGGCCAAGGGGGAAATAGGCCAGCTGCAAACAGACCCTG
AGTATGCCAGTATCAGAAAAGTTATCGGGGATTGTGTAGATTACCTCCAGCCTCAGGCCCAGAAGATGCAAAAACGGATA
GCACTGAATGTTAGCGTGGATATTCCCTTGACATTATTTGATAAAAAAATGATTTATCAGGTGGTGCTTAATCTGCTCAG
CAACTCACTTAAGTTTTCCCGTACCGGCAGTGAAATTTGTATTGAGGCCGTGAAATCAGGGGATAAAATCAAAGTTTCGG
TCAAAGACCAGGGTACTGGTATACCCAAGAACAAGCAGCAGGGAATTTTTACTCCTTATTATCGTATCAAGACCAAGCGG
GACAGGTACGGTGGGTTGGGTTTGGGACTAGCTCTTTCTAAGATGATTATTGAACTGCACAGGGGTGAGATATGGTTTAC
CAGTGAATACGGCCATGGCAGTACCTTTTACTTTACACTACCGATAAGGAGCGAATGGGATGAAGACCCTGATAATAGAG
GATGA

Upstream 100 bases:

>100_bases
TTACACAAATGTTAGCCGTATTATTCAATTGTACTTGTTTTTTTTGTATGGTAATATTAGTATGGCTATAAGTAGCGGAT
TGTTGTGGGGGACTCTAGCC

Downstream 100 bases:

>100_bases
TTTATCCATAATTGATCTGGTAGTGCTTACCCTTTCGGTAGCCTGGCCAGATATCCAGATAGTTAGAACCCAGCTTGGCA
AAGAGGGCATAGAGCTAGCT

Product: sensory box sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MIDNLDTIQIDTLPVGIVVIDVLSRKIMNINQAAQNLIGAEASEIIGHSCHKFICPAEEGKCPILDMGQSIDNAERQLLT
SSSKLITILKTASKVTINGRDFLYEVLQDVTDPVNLRKQLQIQVAERTKELAEINSKLVQEIKNHEKTERKLNELFTRYS
MFFNNCNDGLTLIDFSGGTPPGKYIEVNKAFCQMVNYSREELLQLTPIDLTASEMKDYALGNTKLVLESEYAVLRFPNVY
ITKDGRRLDCEINASFVYLSGREVAVVVYRDISETKRLEQSLREAYERELQAHAEVEDQLNQRNYFMRALVHELKTSLTP
LLAASEYLVSELSDSALLGYARNMQNGAINLNNKIDDLMNLAKGEIGQLQTDPEYASIRKVIGDCVDYLQPQAQKMQKRI
ALNVSVDIPLTLFDKKMIYQVVLNLLSNSLKFSRTGSEICIEAVKSGDKIKVSVKDQGTGIPKNKQQGIFTPYYRIKTKR
DRYGGLGLGLALSKMIIELHRGEIWFTSEYGHGSTFYFTLPIRSEWDEDPDNRG

Sequences:

>Translated_534_residues
MIDNLDTIQIDTLPVGIVVIDVLSRKIMNINQAAQNLIGAEASEIIGHSCHKFICPAEEGKCPILDMGQSIDNAERQLLT
SSSKLITILKTASKVTINGRDFLYEVLQDVTDPVNLRKQLQIQVAERTKELAEINSKLVQEIKNHEKTERKLNELFTRYS
MFFNNCNDGLTLIDFSGGTPPGKYIEVNKAFCQMVNYSREELLQLTPIDLTASEMKDYALGNTKLVLESEYAVLRFPNVY
ITKDGRRLDCEINASFVYLSGREVAVVVYRDISETKRLEQSLREAYERELQAHAEVEDQLNQRNYFMRALVHELKTSLTP
LLAASEYLVSELSDSALLGYARNMQNGAINLNNKIDDLMNLAKGEIGQLQTDPEYASIRKVIGDCVDYLQPQAQKMQKRI
ALNVSVDIPLTLFDKKMIYQVVLNLLSNSLKFSRTGSEICIEAVKSGDKIKVSVKDQGTGIPKNKQQGIFTPYYRIKTKR
DRYGGLGLGLALSKMIIELHRGEIWFTSEYGHGSTFYFTLPIRSEWDEDPDNRG
>Mature_534_residues
MIDNLDTIQIDTLPVGIVVIDVLSRKIMNINQAAQNLIGAEASEIIGHSCHKFICPAEEGKCPILDMGQSIDNAERQLLT
SSSKLITILKTASKVTINGRDFLYEVLQDVTDPVNLRKQLQIQVAERTKELAEINSKLVQEIKNHEKTERKLNELFTRYS
MFFNNCNDGLTLIDFSGGTPPGKYIEVNKAFCQMVNYSREELLQLTPIDLTASEMKDYALGNTKLVLESEYAVLRFPNVY
ITKDGRRLDCEINASFVYLSGREVAVVVYRDISETKRLEQSLREAYERELQAHAEVEDQLNQRNYFMRALVHELKTSLTP
LLAASEYLVSELSDSALLGYARNMQNGAINLNNKIDDLMNLAKGEIGQLQTDPEYASIRKVIGDCVDYLQPQAQKMQKRI
ALNVSVDIPLTLFDKKMIYQVVLNLLSNSLKFSRTGSEICIEAVKSGDKIKVSVKDQGTGIPKNKQQGIFTPYYRIKTKR
DRYGGLGLGLALSKMIIELHRGEIWFTSEYGHGSTFYFTLPIRSEWDEDPDNRG

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=426, Percent_Identity=27.4647887323944, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=30.03663003663, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=29.5546558704453, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081816, Length=236, Percent_Identity=29.2372881355932, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788549, Length=427, Percent_Identity=23.6533957845433, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788713, Length=361, Percent_Identity=26.0387811634349, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=26.2295081967213, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=29.7619047619048, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=27.3148148148148, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788393, Length=242, Percent_Identity=26.8595041322314, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=274, Percent_Identity=25.1824817518248, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=256, Percent_Identity=26.171875, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60410; Mature: 60410

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDNLDTIQIDTLPVGIVVIDVLSRKIMNINQAAQNLIGAEASEIIGHSCHKFICPAEEG
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
KCPILDMGQSIDNAERQLLTSSSKLITILKTASKVTINGRDFLYEVLQDVTDPVNLRKQL
CCCCEECCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCHHHHHHHHHHCCCCHHHHHHH
QIQVAERTKELAEINSKLVQEIKNHEKTERKLNELFTRYSMFFNNCNDGLTLIDFSGGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
PGKYIEVNKAFCQMVNYSREELLQLTPIDLTASEMKDYALGNTKLVLESEYAVLRFPNVY
CCCEEEHHHHHHHHHCCCHHHHHEECCCCCCHHHHHHHCCCCEEEEEECCEEEEECCEEE
ITKDGRRLDCEINASFVYLSGREVAVVVYRDISETKRLEQSLREAYERELQAHAEVEDQL
EECCCCEEEEEEECEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQRNYFMRALVHELKTSLTPLLAASEYLVSELSDSALLGYARNMQNGAINLNNKIDDLMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCHHHHHHH
LAKGEIGQLQTDPEYASIRKVIGDCVDYLQPQAQKMQKRIALNVSVDIPLTLFDKKMIYQ
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCHHHHHHHHHHH
VVLNLLSNSLKFSRTGSEICIEAVKSGDKIKVSVKDQGTGIPKNKQQGIFTPYYRIKTKR
HHHHHHHCCCEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECC
DRYGGLGLGLALSKMIIELHRGEIWFTSEYGHGSTFYFTLPIRSEWDEDPDNRG
CCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MIDNLDTIQIDTLPVGIVVIDVLSRKIMNINQAAQNLIGAEASEIIGHSCHKFICPAEEG
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
KCPILDMGQSIDNAERQLLTSSSKLITILKTASKVTINGRDFLYEVLQDVTDPVNLRKQL
CCCCEECCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCHHHHHHHHHHCCCCHHHHHHH
QIQVAERTKELAEINSKLVQEIKNHEKTERKLNELFTRYSMFFNNCNDGLTLIDFSGGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
PGKYIEVNKAFCQMVNYSREELLQLTPIDLTASEMKDYALGNTKLVLESEYAVLRFPNVY
CCCEEEHHHHHHHHHCCCHHHHHEECCCCCCHHHHHHHCCCCEEEEEECCEEEEECCEEE
ITKDGRRLDCEINASFVYLSGREVAVVVYRDISETKRLEQSLREAYERELQAHAEVEDQL
EECCCCEEEEEEECEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQRNYFMRALVHELKTSLTPLLAASEYLVSELSDSALLGYARNMQNGAINLNNKIDDLMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCHHHHHHH
LAKGEIGQLQTDPEYASIRKVIGDCVDYLQPQAQKMQKRIALNVSVDIPLTLFDKKMIYQ
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCHHHHHHHHHHH
VVLNLLSNSLKFSRTGSEICIEAVKSGDKIKVSVKDQGTGIPKNKQQGIFTPYYRIKTKR
HHHHHHHCCCEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECC
DRYGGLGLGLALSKMIIELHRGEIWFTSEYGHGSTFYFTLPIRSEWDEDPDNRG
CCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]