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The map label for this gene is atpH

Identifier: 57234629

GI number: 57234629

Start: 515689

End: 516231

Strand: Direct

Name: atpH

Synonym: DET0561

Alternate gene names: 57234629

Gene position: 515689-516231 (Clockwise)

Preceding gene: 57234630

Following gene: 57234628

Centisome position: 35.09

GC content: 48.25

Gene sequence:

>543_bases
GTGGCCAAAAGAGTTTATGCTATAGCCATGCGTTATGCGCAGGCATTATACGAACTGGCTAAGGAGCAAAAGTCTCTGGA
TAAGTGGCAGGAAGATTTACAGGATCTTTCCAGCCTCACAGAGGATGCTTCGGTTGCAGAGTTTCTCAGCAACCCCAAAA
TTGCCTCTGCCAGAAAACACAAGGTCCTTGCCAAGCTGAGCAATATAGATCCGCTGATGCTGAACCTGGTGGATATGCTG
GTGGCTACCCGCAGGCTGGGTATCATGAGGGCTGTTTCAGGTGAGTATAACCGTTTGCTGAATGAGGCCAGAGGGGTGGA
GGATGCTATTGTAACCACTGCCAAGCCTTCCAGCGAAGCGGATATTGAAATAATCAGACAGCAGTTAAGCAAGATAACCG
GGAAAAAGATAAATGTAGTAACTGCAACAGACCCCGGCTTGATAGCTGGTCTGAAAGCCAGAATCGGGGATAAACTGATA
GATGGTTCTGTCAGCCGGAGGCTGGTCTTACTGCAAAACGAAATCAGTCAGGGACGTATTTGA

Upstream 100 bases:

>100_bases
ACCAATCTTTAGATAAAAAGGCGCATCAGGCGCTGATTGACAGTGTGCTTGAAAATAGCACCAACCTGCGGAAAAATTAA
AAGAGAGCAACGGAGAAGCA

Downstream 100 bases:

>100_bases
TAACCCTCAGGAGGTGGCGTAATTGAGCGCACGTGGTCAAGATATAGTATCTATTATTAAAGAGCAGATAAAAGAATTCG
GGGCTCCGGTCAGTATGACC

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MAKRVYAIAMRYAQALYELAKEQKSLDKWQEDLQDLSSLTEDASVAEFLSNPKIASARKHKVLAKLSNIDPLMLNLVDML
VATRRLGIMRAVSGEYNRLLNEARGVEDAIVTTAKPSSEADIEIIRQQLSKITGKKINVVTATDPGLIAGLKARIGDKLI
DGSVSRRLVLLQNEISQGRI

Sequences:

>Translated_180_residues
MAKRVYAIAMRYAQALYELAKEQKSLDKWQEDLQDLSSLTEDASVAEFLSNPKIASARKHKVLAKLSNIDPLMLNLVDML
VATRRLGIMRAVSGEYNRLLNEARGVEDAIVTTAKPSSEADIEIIRQQLSKITGKKINVVTATDPGLIAGLKARIGDKLI
DGSVSRRLVLLQNEISQGRI
>Mature_179_residues
AKRVYAIAMRYAQALYELAKEQKSLDKWQEDLQDLSSLTEDASVAEFLSNPKIASARKHKVLAKLSNIDPLMLNLVDMLV
ATRRLGIMRAVSGEYNRLLNEARGVEDAIVTTAKPSSEADIEIIRQQLSKITGKKINVVTATDPGLIAGLKARIGDKLID
GSVSRRLVLLQNEISQGRI

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=170, Percent_Identity=28.8235294117647, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984710, Length=171, Percent_Identity=28.0701754385965, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984717, Length=171, Percent_Identity=28.0701754385965, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320504, Length=174, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_DEHE1 (Q3Z8Z5)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181304.1
- ProteinModelPortal:   Q3Z8Z5
- SMR:   Q3Z8Z5
- STRING:   Q3Z8Z5
- GeneID:   3230097
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0561
- NMPDR:   fig|243164.3.peg.419
- TIGR:   DET0561
- eggNOG:   COG0712
- HOGENOM:   HBG449028
- OMA:   AYDEEAG
- PhylomeDB:   Q3Z8Z5
- ProtClustDB:   PRK13429
- BioCyc:   DETH243164:DET_0561-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19872; Mature: 19741

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRVYAIAMRYAQALYELAKEQKSLDKWQEDLQDLSSLTEDASVAEFLSNPKIASARKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KVLAKLSNIDPLMLNLVDMLVATRRLGIMRAVSGEYNRLLNEARGVEDAIVTTAKPSSEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCH
DIEIIRQQLSKITGKKINVVTATDPGLIAGLKARIGDKLIDGSVSRRLVLLQNEISQGRI
HHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKRVYAIAMRYAQALYELAKEQKSLDKWQEDLQDLSSLTEDASVAEFLSNPKIASARKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KVLAKLSNIDPLMLNLVDMLVATRRLGIMRAVSGEYNRLLNEARGVEDAIVTTAKPSSEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCH
DIEIIRQQLSKITGKKINVVTATDPGLIAGLKARIGDKLIDGSVSRRLVLLQNEISQGRI
HHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA