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The map label for this gene is cobU-2 [H]

Identifier: 57234512

GI number: 57234512

Start: 639298

End: 639864

Strand: Direct

Name: cobU-2 [H]

Synonym: DET0694

Alternate gene names: 57234512

Gene position: 639298-639864 (Clockwise)

Preceding gene: 57234513

Following gene: 57234486

Centisome position: 43.5

GC content: 50.09

Gene sequence:

>567_bases
ATGAATTATTTACTTATCGGCGGTGCCCGCAGCGGCAAAAGCAGTTATGCGGAGGAACTGGCCAAATCCATAGGTGGCAA
TATTGTGTTTGTGGCAACAGCCGAAGCCGGTGATGATGAAATGAAAACCCGTATCCTGCGGCATCAGCAGGCCCGTCCGC
CTGAGTGGGGTCTTATAGAGGCCAGTCTGGGGGTGGGTGAAAAAATAAGCGCTCACGGGAAAAATGCCGATGTGATTATA
CTGGACTGCATTACCCTGCTGGTAAATAACATAATGTGCCGGTATATGCTTGAACATGGTGATGAGCTTACCGGTGATGC
GGCTGACTATCTGGATGCGGCGGTTAAAAAAGAAATAAACGATGTTATAAAAGCTATGGAAAAGACGGGTGCGTCATTTA
TTGTGGTGACCAATGACGTGGGTGCGGGGCTTATCCCCCCTAATGCCATGGCCAGAATTTACCGGGATTTGCTGGGCAGG
GCAAACCAGATGCTGGGTGCATATGTGGAATATGTGTACCTTATGGTGGCCGGACTGCCCATGCAGGTTAAGCCTTTGCT
CCGCTAG

Upstream 100 bases:

>100_bases
AGGGGTCTATACTGGAAAAACTGAACGATAAATCCCATCTGGGCTGATTTTTAACTTTTGTTCAGGCAGGGCGTTTTTAT
AATACCGGAGGGTCATTAAA

Downstream 100 bases:

>100_bases
GGGCAATTTTATAGTAAAAAGAATATGAAAAACCCCCGCTAAAGACGGGGGCTTTTGTTTATAGGGTATTAAAAAATTTA
CTTCTGGAGTAACTGGTCAA

Product: cobinamide kinase/cobinamide phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MNYLLIGGARSGKSSYAEELAKSIGGNIVFVATAEAGDDEMKTRILRHQQARPPEWGLIEASLGVGEKISAHGKNADVII
LDCITLLVNNIMCRYMLEHGDELTGDAADYLDAAVKKEINDVIKAMEKTGASFIVVTNDVGAGLIPPNAMARIYRDLLGR
ANQMLGAYVEYVYLMVAGLPMQVKPLLR

Sequences:

>Translated_188_residues
MNYLLIGGARSGKSSYAEELAKSIGGNIVFVATAEAGDDEMKTRILRHQQARPPEWGLIEASLGVGEKISAHGKNADVII
LDCITLLVNNIMCRYMLEHGDELTGDAADYLDAAVKKEINDVIKAMEKTGASFIVVTNDVGAGLIPPNAMARIYRDLLGR
ANQMLGAYVEYVYLMVAGLPMQVKPLLR
>Mature_188_residues
MNYLLIGGARSGKSSYAEELAKSIGGNIVFVATAEAGDDEMKTRILRHQQARPPEWGLIEASLGVGEKISAHGKNADVII
LDCITLLVNNIMCRYMLEHGDELTGDAADYLDAAVKKEINDVIKAMEKTGASFIVVTNDVGAGLIPPNAMARIYRDLLGR
ANQMLGAYVEYVYLMVAGLPMQVKPLLR

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=186, Percent_Identity=37.0967741935484, Blast_Score=129, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20383; Mature: 20383

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLLIGGARSGKSSYAEELAKSIGGNIVFVATAEAGDDEMKTRILRHQQARPPEWGLIE
CCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
ASLGVGEKISAHGKNADVIILDCITLLVNNIMCRYMLEHGDELTGDAADYLDAAVKKEIN
ECCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
DVIKAMEKTGASFIVVTNDVGAGLIPPNAMARIYRDLLGRANQMLGAYVEYVYLMVAGLP
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MQVKPLLR
CCHHHCCC
>Mature Secondary Structure
MNYLLIGGARSGKSSYAEELAKSIGGNIVFVATAEAGDDEMKTRILRHQQARPPEWGLIE
CCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
ASLGVGEKISAHGKNADVIILDCITLLVNNIMCRYMLEHGDELTGDAADYLDAAVKKEIN
ECCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
DVIKAMEKTGASFIVVTNDVGAGLIPPNAMARIYRDLLGRANQMLGAYVEYVYLMVAGLP
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MQVKPLLR
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]