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The map label for this gene is hppA [H]

Identifier: 57234413

GI number: 57234413

Start: 720532

End: 722571

Strand: Direct

Name: hppA [H]

Synonym: DET0784

Alternate gene names: 57234413

Gene position: 720532-722571 (Clockwise)

Preceding gene: 57234414

Following gene: 57234411

Centisome position: 49.03

GC content: 52.11

Gene sequence:

>2040_bases
GTGTCTATCTGGATTGCATTGGTTGTCGGTTTAGCGGGTCTGGTTGTTGCCGGGCTGCTGGCCAGGTTTGTCCTCCGGCA
AGATGAGGGCATATCTAAAGTGAGGGAAATTGCCTCGGCCATCAGGGAAGGTGCCATGGCTTTTATCACCCGTGAATACA
CGGTTATGGCCATCTTCGTAGCGGCAGTGACTATCATACTGGCGTTGTTGCCTTCGCTGGGTTGGCCGGTATCGGTCTCG
TTCCTGTTTGGGGCCTTATGCTCCGGGCTTGCGGGTTTTATTGGCATGAGTATAGCCGTCAGGGCTAATGCGCGTACTAC
TACTGCCGCCAGTCACAGCCTTAATCAAGGCCTGAAATTTTCTTTCAGGGCTGGTTCGGTTATGGGTATGAGTGTGGTTG
GTATCGGTATTATCGGCCTTTCAATAATGTACTTTGCCTTTGGCAGTAACGCAGATTTCCTGCAGATTCTGCCCGGATAT
GGTTTCGGGGCTTCCTCTGTGGCTATCTTTGCCAGAGTGGGCGGCGGTATTTTTACCAAAGCGGCTGATACCGGGGCGGA
TATTGTCGGCAAAGTGGAAAAAGGTATCCCCGAAGATGACCCCCGCAATGCGGCGGTAGTGGCAGACTTTGTGGGTGATA
ACGTGGGTGATGTGGCCGGGATGGGGGCTGACCTTTTTGAATCTTATGTAGATTCCATTATAGCTACCATGGCTCTGGCT
ACTGTCGGCGCTTTCTCAATGAAACTGGGGTATTCGCTTGTCCCGTCTGAGGAAGCGGCTTTCTTCCTGCCCATGCTGGT
TGCAGCCGGGGGTATACTGGCCTCGGTTATCGGTATCTTTTTGGTACGTACCGGGGAAAAACTCCAGATGAAGGCCTTGC
TGGCAGCTTTACGCAAGGGTACTCTGGCAGCCGCCTTTTTATCGGCGGTATTCTCTTTCCTGGCTGTCTGGTATCTTCAG
GCAGATTTGGGTCTCTTTGTTGCCATTCTGGCCGGGCTGGCGGCGGGTGTATTTATCGGTGAAAGCACCAACTATTTTAC
TTCATATGTCTATAAACCCACTCTGGGTATAGCGGCATCCTGCCAGACGGGTGCGGCCACCAATATTATTTCCGGTTTTT
CGGTGGGGCTGTTGAGTGTAGTCCCTCCGATAATTCTGGTAGTCGCCGCTATTGTCATTGCTTATACTTTCGGTGATGTT
TACGGTGTGGCTCTGGCCGGTGTGGGTATGCTGGCTACCCTGGGTATTCAGGACGCTACCGATGCGTACGGCCCGGTAGC
TGACAATGCCGGCGGTATAGCTGAAATGGCGGGTTTGCCCAAGGAAGTACGCGAACGGACGGATGCGCTTGATTCTCTGG
GCAATACCACTGCCGCCATAGGCAAAGGGTTTGCCATAGGTTCTGCCGGGCTTACTTCACTGGCTCTTTTGCTTTCTTAC
ACCCAGGCGGTTGGTATAACTGCTTCGCAGGTAAGCCTGCTGGATGTCAAGGTGCTGGCCGGGCTTTTGCTGGGTGTTAT
GATGCCGGCTGTTTTCTGTTCACTTACTTTAAAAGCAGTGGGTGTGACCAGTTTTTCCATTGTGAACGAAGTGCGGCGTC
AGTTTAAAGAGATTGCCGGTATTATGGACGGCACTGCCAAACCCGAATACGGCAAATGTGTAGATATCTGCACCCGTGAC
TCCATTAAGCAGATGATTTTGCCCGGTATTATCACGGTAGTTTCACCGGTAATAGTCGGCTGGCTGCTTGGTTCGGTAGC
CGTAGTGGGTTTTCTGGCCGGTATCATACTGTGCGGGTTTGTACTGGCAGTCACTTTTGCCAATGCCGGCGGTGCCTGGG
ACAATGCCAAGAAATGGGTTGAAACCGGGGCTTACGGCGGTAAAGGTTCGGATGCCCATAAAGCGGCAGTGGTGGGTGAT
ACGGTGGGCGACCCCATGAAGGATACCGCCGGACCGTCACTTAATATTATGATTAAGCTGGTTGCCATTATTGCCTTGGT
TATGGCACCTATACTGGCTAATTTTAGCGGTATAATTTAA

Upstream 100 bases:

>100_bases
CGCACCCGAAGTGATTTAACGTTATATATACAGCAAAAGGGGCTTGAGCAAAAGCTGGAAGATTTCCAGTCAAAATTGAC
CCGGAAAGGGGAGTAATTTA

Downstream 100 bases:

>100_bases
GGCTATATAAAGCTAAATAAACGGGTTGCCGGCCTTTTCTCTGCCAATGGTTGTTTCCCGGCCGTGTCCGGGGAAGACAA
GGGTTTCAGGGGGAAGGCTG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MSIWIALVVGLAGLVVAGLLARFVLRQDEGISKVREIASAIREGAMAFITREYTVMAIFVAAVTIILALLPSLGWPVSVS
FLFGALCSGLAGFIGMSIAVRANARTTTAASHSLNQGLKFSFRAGSVMGMSVVGIGIIGLSIMYFAFGSNADFLQILPGY
GFGASSVAIFARVGGGIFTKAADTGADIVGKVEKGIPEDDPRNAAVVADFVGDNVGDVAGMGADLFESYVDSIIATMALA
TVGAFSMKLGYSLVPSEEAAFFLPMLVAAGGILASVIGIFLVRTGEKLQMKALLAALRKGTLAAAFLSAVFSFLAVWYLQ
ADLGLFVAILAGLAAGVFIGESTNYFTSYVYKPTLGIAASCQTGAATNIISGFSVGLLSVVPPIILVVAAIVIAYTFGDV
YGVALAGVGMLATLGIQDATDAYGPVADNAGGIAEMAGLPKEVRERTDALDSLGNTTAAIGKGFAIGSAGLTSLALLLSY
TQAVGITASQVSLLDVKVLAGLLLGVMMPAVFCSLTLKAVGVTSFSIVNEVRRQFKEIAGIMDGTAKPEYGKCVDICTRD
SIKQMILPGIITVVSPVIVGWLLGSVAVVGFLAGIILCGFVLAVTFANAGGAWDNAKKWVETGAYGGKGSDAHKAAVVGD
TVGDPMKDTAGPSLNIMIKLVAIIALVMAPILANFSGII

Sequences:

>Translated_679_residues
MSIWIALVVGLAGLVVAGLLARFVLRQDEGISKVREIASAIREGAMAFITREYTVMAIFVAAVTIILALLPSLGWPVSVS
FLFGALCSGLAGFIGMSIAVRANARTTTAASHSLNQGLKFSFRAGSVMGMSVVGIGIIGLSIMYFAFGSNADFLQILPGY
GFGASSVAIFARVGGGIFTKAADTGADIVGKVEKGIPEDDPRNAAVVADFVGDNVGDVAGMGADLFESYVDSIIATMALA
TVGAFSMKLGYSLVPSEEAAFFLPMLVAAGGILASVIGIFLVRTGEKLQMKALLAALRKGTLAAAFLSAVFSFLAVWYLQ
ADLGLFVAILAGLAAGVFIGESTNYFTSYVYKPTLGIAASCQTGAATNIISGFSVGLLSVVPPIILVVAAIVIAYTFGDV
YGVALAGVGMLATLGIQDATDAYGPVADNAGGIAEMAGLPKEVRERTDALDSLGNTTAAIGKGFAIGSAGLTSLALLLSY
TQAVGITASQVSLLDVKVLAGLLLGVMMPAVFCSLTLKAVGVTSFSIVNEVRRQFKEIAGIMDGTAKPEYGKCVDICTRD
SIKQMILPGIITVVSPVIVGWLLGSVAVVGFLAGIILCGFVLAVTFANAGGAWDNAKKWVETGAYGGKGSDAHKAAVVGD
TVGDPMKDTAGPSLNIMIKLVAIIALVMAPILANFSGII
>Mature_678_residues
SIWIALVVGLAGLVVAGLLARFVLRQDEGISKVREIASAIREGAMAFITREYTVMAIFVAAVTIILALLPSLGWPVSVSF
LFGALCSGLAGFIGMSIAVRANARTTTAASHSLNQGLKFSFRAGSVMGMSVVGIGIIGLSIMYFAFGSNADFLQILPGYG
FGASSVAIFARVGGGIFTKAADTGADIVGKVEKGIPEDDPRNAAVVADFVGDNVGDVAGMGADLFESYVDSIIATMALAT
VGAFSMKLGYSLVPSEEAAFFLPMLVAAGGILASVIGIFLVRTGEKLQMKALLAALRKGTLAAAFLSAVFSFLAVWYLQA
DLGLFVAILAGLAAGVFIGESTNYFTSYVYKPTLGIAASCQTGAATNIISGFSVGLLSVVPPIILVVAAIVIAYTFGDVY
GVALAGVGMLATLGIQDATDAYGPVADNAGGIAEMAGLPKEVRERTDALDSLGNTTAAIGKGFAIGSAGLTSLALLLSYT
QAVGITASQVSLLDVKVLAGLLLGVMMPAVFCSLTLKAVGVTSFSIVNEVRRQFKEIAGIMDGTAKPEYGKCVDICTRDS
IKQMILPGIITVVSPVIVGWLLGSVAVVGFLAGIILCGFVLAVTFANAGGAWDNAKKWVETGAYGGKGSDAHKAAVVGDT
VGDPMKDTAGPSLNIMIKLVAIIALVMAPILANFSGII

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 69498; Mature: 69366

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIWIALVVGLAGLVVAGLLARFVLRQDEGISKVREIASAIREGAMAFITREYTVMAIFV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVTIILALLPSLGWPVSVSFLFGALCSGLAGFIGMSIAVRANARTTTAASHSLNQGLKF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCEE
SFRAGSVMGMSVVGIGIIGLSIMYFAFGSNADFLQILPGYGFGASSVAIFARVGGGIFTK
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEC
AADTGADIVGKVEKGIPEDDPRNAAVVADFVGDNVGDVAGMGADLFESYVDSIIATMALA
CCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
TVGAFSMKLGYSLVPSEEAAFFLPMLVAAGGILASVIGIFLVRTGEKLQMKALLAALRKG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLAAAFLSAVFSFLAVWYLQADLGLFVAILAGLAAGVFIGESTNYFTSYVYKPTLGIAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCC
CQTGAATNIISGFSVGLLSVVPPIILVVAAIVIAYTFGDVYGVALAGVGMLATLGIQDAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAYGPVADNAGGIAEMAGLPKEVRERTDALDSLGNTTAAIGKGFAIGSAGLTSLALLLSY
CCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHH
TQAVGITASQVSLLDVKVLAGLLLGVMMPAVFCSLTLKAVGVTSFSIVNEVRRQFKEIAG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMDGTAKPEYGKCVDICTRDSIKQMILPGIITVVSPVIVGWLLGSVAVVGFLAGIILCGF
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAVTFANAGGAWDNAKKWVETGAYGGKGSDAHKAAVVGDTVGDPMKDTAGPSLNIMIKL
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHCCCCCHHHHHHH
VAIIALVMAPILANFSGII
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIWIALVVGLAGLVVAGLLARFVLRQDEGISKVREIASAIREGAMAFITREYTVMAIFV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVTIILALLPSLGWPVSVSFLFGALCSGLAGFIGMSIAVRANARTTTAASHSLNQGLKF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCEE
SFRAGSVMGMSVVGIGIIGLSIMYFAFGSNADFLQILPGYGFGASSVAIFARVGGGIFTK
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEC
AADTGADIVGKVEKGIPEDDPRNAAVVADFVGDNVGDVAGMGADLFESYVDSIIATMALA
CCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
TVGAFSMKLGYSLVPSEEAAFFLPMLVAAGGILASVIGIFLVRTGEKLQMKALLAALRKG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLAAAFLSAVFSFLAVWYLQADLGLFVAILAGLAAGVFIGESTNYFTSYVYKPTLGIAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCC
CQTGAATNIISGFSVGLLSVVPPIILVVAAIVIAYTFGDVYGVALAGVGMLATLGIQDAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAYGPVADNAGGIAEMAGLPKEVRERTDALDSLGNTTAAIGKGFAIGSAGLTSLALLLSY
CCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHH
TQAVGITASQVSLLDVKVLAGLLLGVMMPAVFCSLTLKAVGVTSFSIVNEVRRQFKEIAG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMDGTAKPEYGKCVDICTRDSIKQMILPGIITVVSPVIVGWLLGSVAVVGFLAGIILCGF
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAVTFANAGGAWDNAKKWVETGAYGGKGSDAHKAAVVGDTVGDPMKDTAGPSLNIMIKL
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHCCCCCHHHHHHH
VAIIALVMAPILANFSGII
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]