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The map label for this gene is dapB

Identifier: 57234210

GI number: 57234210

Start: 891471

End: 892262

Strand: Direct

Name: dapB

Synonym: DET0971

Alternate gene names: 57234210

Gene position: 891471-892262 (Clockwise)

Preceding gene: 57234211

Following gene: 57234209

Centisome position: 60.66

GC content: 50.88

Gene sequence:

>792_bases
ATGACACCTATAAAGGTTGTAGTTCACGGTGCCTCAGGCAAAATGGGCCAGGAGGTCTTAAAGACCCTGTGCCAGGAAAA
TAACCTTCTTCCGGTGGGAGCAGTGGACATACGGGCAAAAAGCCCTGCCCTGCCCCTGCCGGACGGAAGCGGCTCTATCC
CCTATTCGGCAGACCTCTCTTCCGTTCTTTCGCAGACCAAGCCGGATGTAATGGTAGATTTTACTATTGCCAAAGCTTCC
ATGCCTGCTATCCGCATTGCCGCCGCCCACAAGGTTAATCTGGTTATAGGCACTACCGGCTTTTCGCCTGAGGAAATATC
AGAAATTGAACAGCTGGCTAAAACTAATGATATCGGCATTATAGTTGCACCCAACTTTGCCCTTGGTGCTATAATAATGG
TTCACTTGGCACAGGAAGCATCACGTTTCCTTGCCAGCGCCGAAGTGATAGAGCTGCATCACGATAAGAAACTGGACTCA
CCTTCCGGTACTGCGCTGGCTACAGCAGCCGCCATGCTTAAAACCCGGGGTGAAGCCTTTAACAAACCGGCTAAGGAAAA
TATGTCAGATGCCCGCGGACAGGAACATGACGGCATCCGGGTGCACAGTGTGCGCCTGCCGGGTTTGCTGGCCCATCAGG
AAGTTATTTTCGGAGCGGCCGGTCAATCTTTGACTATACGGCATGATGCCTTCAGCCGCGAATGTTATATGCCCGGTGTG
GTACTGGCGATAAAAGAAATAGTCCAAACCAAAGGTTTTGTTTTCGGTCTGGACAAACTGCTTAAGCTTTAG

Upstream 100 bases:

>100_bases
AATGCTGTTCCCATCTCCCGCAACCGTGATTCCCAGCCGCGCCGTTCCGGGCCTTTCCGCCCTCAAGACCGGTCTAACTC
ATAATATATTAGGAGGCGCT

Downstream 100 bases:

>100_bases
GAGGCAGTCCATGGGTTACAGAGTGGCCATAGTAGGTGCTACCGGAATGGTAGGTCAGGAATTTATAAAAGTACTGGAGA
AACGGGATTTTCCTATGGAT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTPIKVVVHGASGKMGQEVLKTLCQENNLLPVGAVDIRAKSPALPLPDGSGSIPYSADLSSVLSQTKPDVMVDFTIAKAS
MPAIRIAAAHKVNLVIGTTGFSPEEISEIEQLAKTNDIGIIVAPNFALGAIIMVHLAQEASRFLASAEVIELHHDKKLDS
PSGTALATAAAMLKTRGEAFNKPAKENMSDARGQEHDGIRVHSVRLPGLLAHQEVIFGAAGQSLTIRHDAFSRECYMPGV
VLAIKEIVQTKGFVFGLDKLLKL

Sequences:

>Translated_263_residues
MTPIKVVVHGASGKMGQEVLKTLCQENNLLPVGAVDIRAKSPALPLPDGSGSIPYSADLSSVLSQTKPDVMVDFTIAKAS
MPAIRIAAAHKVNLVIGTTGFSPEEISEIEQLAKTNDIGIIVAPNFALGAIIMVHLAQEASRFLASAEVIELHHDKKLDS
PSGTALATAAAMLKTRGEAFNKPAKENMSDARGQEHDGIRVHSVRLPGLLAHQEVIFGAAGQSLTIRHDAFSRECYMPGV
VLAIKEIVQTKGFVFGLDKLLKL
>Mature_262_residues
TPIKVVVHGASGKMGQEVLKTLCQENNLLPVGAVDIRAKSPALPLPDGSGSIPYSADLSSVLSQTKPDVMVDFTIAKASM
PAIRIAAAHKVNLVIGTTGFSPEEISEIEQLAKTNDIGIIVAPNFALGAIIMVHLAQEASRFLASAEVIELHHDKKLDSP
SGTALATAAAMLKTRGEAFNKPAKENMSDARGQEHDGIRVHSVRLPGLLAHQEVIFGAAGQSLTIRHDAFSRECYMPGVV
LAIKEIVQTKGFVFGLDKLLKL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=274, Percent_Identity=29.5620437956204, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_DEHE1 (Q3Z7V5)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181694.1
- ProteinModelPortal:   Q3Z7V5
- SMR:   Q3Z7V5
- STRING:   Q3Z7V5
- GeneID:   3229677
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0971
- NMPDR:   fig|243164.3.peg.385
- TIGR:   DET0971
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   YNNENIE
- ProtClustDB:   PRK00048
- BioCyc:   DETH243164:DET_0971-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27944; Mature: 27813

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPIKVVVHGASGKMGQEVLKTLCQENNLLPVGAVDIRAKSPALPLPDGSGSIPYSADLS
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCEECEEEEECCCCCCCCCCCCCCCCCCCCHH
SVLSQTKPDVMVDFTIAKASMPAIRIAAAHKVNLVIGTTGFSPEEISEIEQLAKTNDIGI
HHHHCCCCCEEEEEEECCCCCCEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEE
IVAPNFALGAIIMVHLAQEASRFLASAEVIELHHDKKLDSPSGTALATAAAMLKTRGEAF
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
NKPAKENMSDARGQEHDGIRVHSVRLPGLLAHQEVIFGAAGQSLTIRHDAFSRECYMPGV
CCCHHHCHHHHCCCCCCCEEEEEEECCCHHHHHHHEEECCCCEEEEECCCCCCCCCCCHH
VLAIKEIVQTKGFVFGLDKLLKL
HHHHHHHHHHCCHHEEHHHHHCC
>Mature Secondary Structure 
TPIKVVVHGASGKMGQEVLKTLCQENNLLPVGAVDIRAKSPALPLPDGSGSIPYSADLS
CCEEEEEECCCCCHHHHHHHHHHHCCCCCEECEEEEECCCCCCCCCCCCCCCCCCCCHH
SVLSQTKPDVMVDFTIAKASMPAIRIAAAHKVNLVIGTTGFSPEEISEIEQLAKTNDIGI
HHHHCCCCCEEEEEEECCCCCCEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEE
IVAPNFALGAIIMVHLAQEASRFLASAEVIELHHDKKLDSPSGTALATAAAMLKTRGEAF
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
NKPAKENMSDARGQEHDGIRVHSVRLPGLLAHQEVIFGAAGQSLTIRHDAFSRECYMPGV
CCCHHHCHHHHCCCCCCCEEEEEEECCCHHHHHHHEEECCCCEEEEECCCCCCCCCCCHH
VLAIKEIVQTKGFVFGLDKLLKL
HHHHHHHHHHCCHHEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA