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The map label for this gene is asd [H]

Identifier: 57234209

GI number: 57234209

Start: 892273

End: 893289

Strand: Direct

Name: asd [H]

Synonym: DET0972

Alternate gene names: 57234209

Gene position: 892273-893289 (Clockwise)

Preceding gene: 57234210

Following gene: 57234208

Centisome position: 60.71

GC content: 50.34

Gene sequence:

>1017_bases
ATGGGTTACAGAGTGGCCATAGTAGGTGCTACCGGAATGGTAGGTCAGGAATTTATAAAAGTACTGGAGAAACGGGATTT
TCCTATGGATACCGTTTCACTCCTGGCGTCAGACCGCTCTGCGGGCAAGAAAATGATGGTCAAAGGCGAGGAAATAGAGG
TCAGGGAGACCGCCTATGATTCGTTTAATAACGTGGATATAGCTTTGTTCTCTGCCGGGGCGGATATTTCACGCCATTTT
GCCCCCATTGCCGCCCAGCACAAAGCAATAGTAGTAGATAACAGTGCCGCTTTCCGCATGGACCCCAAAGTCCCCCTGGT
AGTACCGGAAGTGAATATTGAAGATATTACCAGGCATAAAGGGATTATTGCCAACCCCAATTGCTCTACCATTCAGATGG
TAGTCGCCCTGTACCCTCTGCACAAGGTAAATCCAATTAAACGTATTGTGGTAACTACCTTTCAGGCTGTGTCCGGCACG
GGCGTAAACGCGGTAGATGAGCTGCAAACCCAAACCCGCCAGCTCCTTGACGGACAGAAAGCGGTTGCCCATGTATATTC
CCACCAGATTGCCTTTAATGTGCTGCCGGAGATTGACGTTTTTCTGGACAGCGGCTATACCAAGGAAGAATGGAAAATGC
TGGAAGAAACCCGCAAGATTATGCATGCTGACAACATACAGCTTTCAGCTACCTGCGTAAGAGTACCGGTTATCACCGGC
CATTCTGAAGCTGTAACTATAGAATTTGAACGTCCCATGGAGCCGGAACAGGCCCGGGATATACTCCTTCGGTCACCGGG
TATAAAAGTACTGGACGAACCGGCTGTCAAACTTTATCCGCACCCCTGGCTGGCCACCGGTACAGACGAGGTATTTGTGG
GACGGATACGCAAAGACATTTCCAACCCCAATGGTTTGGTTATGTGGGTGGTGGCGGACAATGTCCGGAAAGGCGCGGCC
CTAAACGCCGTCCAGATTGCCGAAGAACTGGTCAACCGCGGCATGATAGGAGGTTAA

Upstream 100 bases:

>100_bases
TGTTATATGCCCGGTGTGGTACTGGCGATAAAAGAAATAGTCCAAACCAAAGGTTTTGTTTTCGGTCTGGACAAACTGCT
TAAGCTTTAGGAGGCAGTCC

Downstream 100 bases:

>100_bases
GATGAAAGAATTAGGCAGGCTGATTACGGCCATGGTAACCCCGTTTAAAAAAGACGGGACAGTAGATTATGCCCAGGCTC
AGAAACTGGCTCTGGGACTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MGYRVAIVGATGMVGQEFIKVLEKRDFPMDTVSLLASDRSAGKKMMVKGEEIEVRETAYDSFNNVDIALFSAGADISRHF
APIAAQHKAIVVDNSAAFRMDPKVPLVVPEVNIEDITRHKGIIANPNCSTIQMVVALYPLHKVNPIKRIVVTTFQAVSGT
GVNAVDELQTQTRQLLDGQKAVAHVYSHQIAFNVLPEIDVFLDSGYTKEEWKMLEETRKIMHADNIQLSATCVRVPVITG
HSEAVTIEFERPMEPEQARDILLRSPGIKVLDEPAVKLYPHPWLATGTDEVFVGRIRKDISNPNGLVMWVVADNVRKGAA
LNAVQIAEELVNRGMIGG

Sequences:

>Translated_338_residues
MGYRVAIVGATGMVGQEFIKVLEKRDFPMDTVSLLASDRSAGKKMMVKGEEIEVRETAYDSFNNVDIALFSAGADISRHF
APIAAQHKAIVVDNSAAFRMDPKVPLVVPEVNIEDITRHKGIIANPNCSTIQMVVALYPLHKVNPIKRIVVTTFQAVSGT
GVNAVDELQTQTRQLLDGQKAVAHVYSHQIAFNVLPEIDVFLDSGYTKEEWKMLEETRKIMHADNIQLSATCVRVPVITG
HSEAVTIEFERPMEPEQARDILLRSPGIKVLDEPAVKLYPHPWLATGTDEVFVGRIRKDISNPNGLVMWVVADNVRKGAA
LNAVQIAEELVNRGMIGG
>Mature_337_residues
GYRVAIVGATGMVGQEFIKVLEKRDFPMDTVSLLASDRSAGKKMMVKGEEIEVRETAYDSFNNVDIALFSAGADISRHFA
PIAAQHKAIVVDNSAAFRMDPKVPLVVPEVNIEDITRHKGIIANPNCSTIQMVVALYPLHKVNPIKRIVVTTFQAVSGTG
VNAVDELQTQTRQLLDGQKAVAHVYSHQIAFNVLPEIDVFLDSGYTKEEWKMLEETRKIMHADNIQLSATCVRVPVITGH
SEAVTIEFERPMEPEQARDILLRSPGIKVLDEPAVKLYPHPWLATGTDEVFVGRIRKDISNPNGLVMWVVADNVRKGAAL
NAVQIAEELVNRGMIGG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=36.4985163204748, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=26.7605633802817, Blast_Score=98, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=397, Percent_Identity=29.9748110831234, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37259; Mature: 37128

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRVAIVGATGMVGQEFIKVLEKRDFPMDTVSLLASDRSAGKKMMVKGEEIEVRETAYD
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCEEEEHHHHCC
SFNNVDIALFSAGADISRHFAPIAAQHKAIVVDNSAAFRMDPKVPLVVPEVNIEDITRHK
CCCCCEEEEEECCCCHHHHHCCHHCCCEEEEEECCCEEEECCCCCEEECCCCHHHHHHCC
GIIANPNCSTIQMVVALYPLHKVNPIKRIVVTTFQAVSGTGVNAVDELQTQTRQLLDGQK
CEEECCCCHHHHHHHHHHCHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHH
AVAHVYSHQIAFNVLPEIDVFLDSGYTKEEWKMLEETRKIMHADNIQLSATCVRVPVITG
HHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEC
HSEAVTIEFERPMEPEQARDILLRSPGIKVLDEPAVKLYPHPWLATGTDEVFVGRIRKDI
CCCEEEEEECCCCCHHHHHHHHHCCCCCCEECCCCEEECCCCCEECCCCHHHHHHHHHHH
SNPNGLVMWVVADNVRKGAALNAVQIAEELVNRGMIGG
CCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GYRVAIVGATGMVGQEFIKVLEKRDFPMDTVSLLASDRSAGKKMMVKGEEIEVRETAYD
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCEEEEHHHHCC
SFNNVDIALFSAGADISRHFAPIAAQHKAIVVDNSAAFRMDPKVPLVVPEVNIEDITRHK
CCCCCEEEEEECCCCHHHHHCCHHCCCEEEEEECCCEEEECCCCCEEECCCCHHHHHHCC
GIIANPNCSTIQMVVALYPLHKVNPIKRIVVTTFQAVSGTGVNAVDELQTQTRQLLDGQK
CEEECCCCHHHHHHHHHHCHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHH
AVAHVYSHQIAFNVLPEIDVFLDSGYTKEEWKMLEETRKIMHADNIQLSATCVRVPVITG
HHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEC
HSEAVTIEFERPMEPEQARDILLRSPGIKVLDEPAVKLYPHPWLATGTDEVFVGRIRKDI
CCCEEEEEECCCCCHHHHHHHHHCCCCCCEECCCCEEECCCCCEECCCCHHHHHHHHHHH
SNPNGLVMWVVADNVRKGAALNAVQIAEELVNRGMIGG
CCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]