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The map label for this gene is degP [C]

Identifier: 57234203

GI number: 57234203

Start: 940964

End: 942085

Strand: Direct

Name: degP [C]

Synonym: DET1037

Alternate gene names: 57234203

Gene position: 940964-942085 (Clockwise)

Preceding gene: 57234204

Following gene: 57234184

Centisome position: 64.02

GC content: 50.89

Gene sequence:

>1122_bases
ATGAAAAAGAAACAAAAATTATTAAGTCTGTTTCTGGGCATAGTACTTGTTGTTAGTGTTCTCAGCGGAGGCTGTGATTA
CTTATCCCAGCCTATAAACTCTGACAATACCGACAGCACTTCTACCCCTATTGATGCAGACTGGACATTCCCCACTCCCC
AGCAGAATCTGCCGGAACTGGCCAACTATGCCATGGTGGTTGCCATGGTAAAACCAGCCGTGGTAGCGGTAGATGTGGAA
TACATAACCCAGGATATATTCGGCCGCCAAACGGTTGCCGTAGCCTCAGGTTCGGGTTTCATAATAGACCCCAGCGGCTA
TATTATTACCAACAACCACGTAGTTGAAGGCGGAAGCACTGTCACCGTCACCCTTTCAGACGGCCGTACCTTTACCGCCA
GCCAGGTGGTAACAGATTCACGCACAGACCTGGCGGTAATCAAGGTGGATACACTGGGTGAAGACCTGCCGTTTGTATAT
ATAGGTGATTCGTCAGCTTTGGAAGTAGGCGAACCGGTGGCGGCTATCGGCAATGCATTGGGGCTGGGGATAACCATGAA
AGGCGGCTGGATAAGCCGTCTGGATGCCCAGATAACCGTTGACCAGAGTGTAACCCTGTACGGTTTGATAGGTACAGATG
TAGCCATAAACGAAGGCAATTCCGGCGGCCCGCTGGTAAATATGGCCGGTGAGGTTATCGGCATTACCTCTGCCAAAATA
GCGGAAGTGGGGGTGGAAGGGGTAGGCTACGCTATAAATATAAACTCCGCCCGCACCTTCATTGAAGAGCTGGTCAAAAA
AGGCTATATTACCCGGCCTTTTATGGGAGTGGCCGGCATACTGACCGTAGACAGTTCAATCCAGTCATACTTCAGGCTGG
GCATAGACAGAGGGGTGCTTATCCGGGGCGTGTCTGAAGGCGGACCCGCCGAAAAAGCAGGTCTAATGGCAAATGATGTT
ATTCTGGCCATAAACGGCCAGCCAGTGCTGACTGATGAAGAACTGATACTAGCTATCCACGGCAAAAAGATAGGCGATAA
AATAGAGGTCAGCTATTTCCGGGACGGAGTAACCGCTACTGTCACTCTGACACTGGCAGAGACCCCGCCGCCGGAAAGCT
AG

Upstream 100 bases:

>100_bases
AGGAGGTAGGGGTGGAGGGCATCGGCTATGCTATCAGCCTGTATATAGCTTTGCCCATTATCAATAACCTTATCTCCCAG
CTGCCGGCTTGAGCAAAACT

Downstream 100 bases:

>100_bases
TTTTTTAGTTTTTTAGCGTGCCACCCACAGGCTTAGGGAGTGGCCGTCAATATCCAGACTTTCAGCATACGCCCCTTCGG
GGGCGTTTCCCTTTATAAGC

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKKKQKLLSLFLGIVLVVSVLSGGCDYLSQPINSDNTDSTSTPIDADWTFPTPQQNLPELANYAMVVAMVKPAVVAVDVE
YITQDIFGRQTVAVASGSGFIIDPSGYIITNNHVVEGGSTVTVTLSDGRTFTASQVVTDSRTDLAVIKVDTLGEDLPFVY
IGDSSALEVGEPVAAIGNALGLGITMKGGWISRLDAQITVDQSVTLYGLIGTDVAINEGNSGGPLVNMAGEVIGITSAKI
AEVGVEGVGYAININSARTFIEELVKKGYITRPFMGVAGILTVDSSIQSYFRLGIDRGVLIRGVSEGGPAEKAGLMANDV
ILAINGQPVLTDEELILAIHGKKIGDKIEVSYFRDGVTATVTLTLAETPPPES

Sequences:

>Translated_373_residues
MKKKQKLLSLFLGIVLVVSVLSGGCDYLSQPINSDNTDSTSTPIDADWTFPTPQQNLPELANYAMVVAMVKPAVVAVDVE
YITQDIFGRQTVAVASGSGFIIDPSGYIITNNHVVEGGSTVTVTLSDGRTFTASQVVTDSRTDLAVIKVDTLGEDLPFVY
IGDSSALEVGEPVAAIGNALGLGITMKGGWISRLDAQITVDQSVTLYGLIGTDVAINEGNSGGPLVNMAGEVIGITSAKI
AEVGVEGVGYAININSARTFIEELVKKGYITRPFMGVAGILTVDSSIQSYFRLGIDRGVLIRGVSEGGPAEKAGLMANDV
ILAINGQPVLTDEELILAIHGKKIGDKIEVSYFRDGVTATVTLTLAETPPPES
>Mature_373_residues
MKKKQKLLSLFLGIVLVVSVLSGGCDYLSQPINSDNTDSTSTPIDADWTFPTPQQNLPELANYAMVVAMVKPAVVAVDVE
YITQDIFGRQTVAVASGSGFIIDPSGYIITNNHVVEGGSTVTVTLSDGRTFTASQVVTDSRTDLAVIKVDTLGEDLPFVY
IGDSSALEVGEPVAAIGNALGLGITMKGGWISRLDAQITVDQSVTLYGLIGTDVAINEGNSGGPLVNMAGEVIGITSAKI
AEVGVEGVGYAININSARTFIEELVKKGYITRPFMGVAGILTVDSSIQSYFRLGIDRGVLIRGVSEGGPAEKAGLMANDV
ILAINGQPVLTDEELILAIHGKKIGDKIEVSYFRDGVTATVTLTLAETPPPES

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=281, Percent_Identity=37.3665480427046, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24308541, Length=297, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI22129776, Length=293, Percent_Identity=32.7645051194539, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7019477, Length=319, Percent_Identity=33.8557993730408, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1786356, Length=277, Percent_Identity=37.1841155234657, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789629, Length=274, Percent_Identity=37.2262773722628, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789630, Length=338, Percent_Identity=34.3195266272189, Blast_Score=149, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24646839, Length=297, Percent_Identity=34.006734006734, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 39111; Mature: 39111

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKQKLLSLFLGIVLVVSVLSGGCDYLSQPINSDNTDSTSTPIDADWTFPTPQQNLPEL
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ANYAMVVAMVKPAVVAVDVEYITQDIFGRQTVAVASGSGFIIDPSGYIITNNHVVEGGST
HHHHEEEEECCCEEEEEEHHHHHHHHCCCEEEEEECCCCEEECCCCEEEECCEEECCCCE
VTVTLSDGRTFTASQVVTDSRTDLAVIKVDTLGEDLPFVYIGDSSALEVGEPVAAIGNAL
EEEEECCCCEEEHHEEEECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHCCHH
GLGITMKGGWISRLDAQITVDQSVTLYGLIGTDVAINEGNSGGPLVNMAGEVIGITSAKI
EEEEEECCCCEEEEEEEEEECCCEEEEEEEECEEEEECCCCCCCEEEECCCEEEECCHHH
AEVGVEGVGYAININSARTFIEELVKKGYITRPFMGVAGILTVDSSIQSYFRLGIDRGVL
HHCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCHHHEEEEEECHHHHHHHHHCCCCCEE
IRGVSEGGPAEKAGLMANDVILAINGQPVLTDEELILAIHGKKIGDKIEVSYFRDGVTAT
EEECCCCCCCHHCCEEECCEEEEECCCEEEECCEEEEEEECCCCCCEEEEEEEECCCEEE
VTLTLAETPPPES
EEEEEECCCCCCC
>Mature Secondary Structure
MKKKQKLLSLFLGIVLVVSVLSGGCDYLSQPINSDNTDSTSTPIDADWTFPTPQQNLPEL
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ANYAMVVAMVKPAVVAVDVEYITQDIFGRQTVAVASGSGFIIDPSGYIITNNHVVEGGST
HHHHEEEEECCCEEEEEEHHHHHHHHCCCEEEEEECCCCEEECCCCEEEECCEEECCCCE
VTVTLSDGRTFTASQVVTDSRTDLAVIKVDTLGEDLPFVYIGDSSALEVGEPVAAIGNAL
EEEEECCCCEEEHHEEEECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHCCHH
GLGITMKGGWISRLDAQITVDQSVTLYGLIGTDVAINEGNSGGPLVNMAGEVIGITSAKI
EEEEEECCCCEEEEEEEEEECCCEEEEEEEECEEEEECCCCCCCEEEECCCEEEECCHHH
AEVGVEGVGYAININSARTFIEELVKKGYITRPFMGVAGILTVDSSIQSYFRLGIDRGVL
HHCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCHHHEEEEEECHHHHHHHHHCCCCCEE
IRGVSEGGPAEKAGLMANDVILAINGQPVLTDEELILAIHGKKIGDKIEVSYFRDGVTAT
EEECCCCCCCHHCCEEECCEEEEECCCEEEECCEEEEEEECCCCCCEEEEEEEECCCEEE
VTLTLAETPPPES
EEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA