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The map label for this gene is regX3 [H]

Identifier: 57234165

GI number: 57234165

Start: 958881

End: 959564

Strand: Direct

Name: regX3 [H]

Synonym: DET1058

Alternate gene names: 57234165

Gene position: 958881-959564 (Clockwise)

Preceding gene: 57234166

Following gene: 57234164

Centisome position: 65.24

GC content: 49.56

Gene sequence:

>684_bases
ATGTCTAAGAAAATACTGATAGCCGATGATGAGAATAAAATAGCCGAAATCCTTAAAGCCTATCTTGAACGCGAAGGCTT
TAAGGTGAGCGTTACCTATAATGGCAAAGAGGCCCTGGCAAAATTCCGTGAAGAGAACCCCGACCTGATAATACTTGACC
TGATGCTGCCCGAAATATCCGGCTGGGATGTCTGCCGCGAAATCCGCAAGGAAAGCCGCGTGCCTATAATCATGCTTACC
GCCCGGGATGAACTTACCGACAAGCTGATAGGGCTGGAAATAGGGGCGGATGACTATATGACCAAACCCTTTGAGGCTAA
AGAACTGGTAGCCCGCGCCAAAGTCCAGCTGAGGCGGTCTGAACACACCCCTGCTTCCGAGCCGGTACTGGTTATTGACC
GCCTGGAAATAGATACGGAACGGCGTTTGGTAAAAATGGACGGGGAGAATATAGACCTGACCGCTACCGAATTTGATATA
CTGGCAAATCTGGCCGCAAGCCCGGGGCGGGTTTTCTCCCGTATGCAAATACTGGACAAACTGGGTGAGGCTTACGAAGG
CTATGAACGCACTATAGACAGCCACATTAAAAATCTGCGTAAAAAAATAGAGCCCGACCCCGAATCCCCAGCCTATATCC
TGACCGTACACGGGGTAGGTTACAAGATGAAAGACAAAGGGTAA

Upstream 100 bases:

>100_bases
CTGCCGGGGCTGTGCAATATTATAGCCGGTAAAGATGGGGGCAGGCCCTAAAAGCCTGCCCCTTGCCGTTTGGCAGTTTA
CATTATAATATGAGAAGAAT

Downstream 100 bases:

>100_bases
AAGAGCGTGTCCCGCTTAAGCTATAAAATTTTCGGTGCCCTGCTGCTGACTGTTTTGCTGTCGGTGGGTCTTACTTCGTT
TGCCGCCAACCAGCTGACCG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSKKILIADDENKIAEILKAYLEREGFKVSVTYNGKEALAKFREENPDLIILDLMLPEISGWDVCREIRKESRVPIIMLT
ARDELTDKLIGLEIGADDYMTKPFEAKELVARAKVQLRRSEHTPASEPVLVIDRLEIDTERRLVKMDGENIDLTATEFDI
LANLAASPGRVFSRMQILDKLGEAYEGYERTIDSHIKNLRKKIEPDPESPAYILTVHGVGYKMKDKG

Sequences:

>Translated_227_residues
MSKKILIADDENKIAEILKAYLEREGFKVSVTYNGKEALAKFREENPDLIILDLMLPEISGWDVCREIRKESRVPIIMLT
ARDELTDKLIGLEIGADDYMTKPFEAKELVARAKVQLRRSEHTPASEPVLVIDRLEIDTERRLVKMDGENIDLTATEFDI
LANLAASPGRVFSRMQILDKLGEAYEGYERTIDSHIKNLRKKIEPDPESPAYILTVHGVGYKMKDKG
>Mature_226_residues
SKKILIADDENKIAEILKAYLEREGFKVSVTYNGKEALAKFREENPDLIILDLMLPEISGWDVCREIRKESRVPIIMLTA
RDELTDKLIGLEIGADDYMTKPFEAKELVARAKVQLRRSEHTPASEPVLVIDRLEIDTERRLVKMDGENIDLTATEFDIL
ANLAASPGRVFSRMQILDKLGEAYEGYERTIDSHIKNLRKKIEPDPESPAYILTVHGVGYKMKDKG

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=42.6086956521739, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=41.7777777777778, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=38.2222222222222, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=39.0350877192982, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=38.695652173913, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=36.1990950226244, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=36.5217391304348, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=38.1165919282511, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=34.3891402714932, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=35.0877192982456, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=35.1111111111111, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=36.322869955157, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=31.0344827586207, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=34.3891402714932, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=36.1111111111111, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=28.030303030303, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=28.7037037037037, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=114, Percent_Identity=35.0877192982456, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25846; Mature: 25715

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKILIADDENKIAEILKAYLEREGFKVSVTYNGKEALAKFREENPDLIILDLMLPEIS
CCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCC
GWDVCREIRKESRVPIIMLTARDELTDKLIGLEIGADDYMTKPFEAKELVARAKVQLRRS
CHHHHHHHHHHCCCCEEEEECCHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
EHTPASEPVLVIDRLEIDTERRLVKMDGENIDLTATEFDILANLAASPGRVFSRMQILDK
CCCCCCCCEEEEEEEEECCCCEEEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
LGEAYEGYERTIDSHIKNLRKKIEPDPESPAYILTVHGVGYKMKDKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEECCCC
>Mature Secondary Structure 
SKKILIADDENKIAEILKAYLEREGFKVSVTYNGKEALAKFREENPDLIILDLMLPEIS
CCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCC
GWDVCREIRKESRVPIIMLTARDELTDKLIGLEIGADDYMTKPFEAKELVARAKVQLRRS
CHHHHHHHHHHCCCCEEEEECCHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
EHTPASEPVLVIDRLEIDTERRLVKMDGENIDLTATEFDILANLAASPGRVFSRMQILDK
CCCCCCCCEEEEEEEEECCCCEEEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
LGEAYEGYERTIDSHIKNLRKKIEPDPESPAYILTVHGVGYKMKDKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA