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The map label for this gene is baeS [H]

Identifier: 57234164

GI number: 57234164

Start: 959571

End: 960992

Strand: Direct

Name: baeS [H]

Synonym: DET1059

Alternate gene names: 57234164

Gene position: 959571-960992 (Clockwise)

Preceding gene: 57234165

Following gene: 57234163

Centisome position: 65.29

GC content: 53.38

Gene sequence:

>1422_bases
GTGTCCCGCTTAAGCTATAAAATTTTCGGTGCCCTGCTGCTGACTGTTTTGCTGTCGGTGGGTCTTACTTCGTTTGCCGC
CAACCAGCTGACCGCCAGCCAGTTCCGCCAGTATATTATCCGGGGGAATACCGAATTTATAACCAGCGTGGAAAGTGCAC
TGGGTACATATTATGCCCAATATCAAGGCTGGGATAACGTAAATGGTGTCCTTATCCAGCTGCTGGGCAGTAACGGCGGG
CGTTTAGTATTAAGCGATGCCAGCGGGCTGATAGTAGCTGACACCCAAAACAAATGGATAGGCTACCAGACAGACGAATA
CAGCCTGTCAAACGGTACTTTGATAAGCATTTCGGGTACAGATGCAGGCTATCTCTACTGGATTGGCAGCCAGGGCAGCG
GCTCCGGCAGCGGTTACGGTAAAGGGATGCAGAGCGGGCAGAACAATAGCGGTAATGCCGCTGCTGGCATAATCAGCGAA
TCCCAGCAGCAACTGCTGGATGAAATGAACAGGTCTATCTGGCTGTCCGGGGGCTTAGCCGGTCTGGCGGCCCTGGGTCT
GGGGCTGCTGCTGGCCAGCCAGATTATCCGTCCGCTTAAAGCCCTCAGCCGGAGTGCCAGACGGATTGCCGGGGGAGAGC
TTTCCCAGCGGGTAAAGGTAGACTCCCGTGACGAACTGGGCGAACTGGCTGAAAGCTTCAACCACATGGCCCAAAGCCTG
GAAACCAACGAACAGTCACGCCAGAGACTGCTGGCTGATATTGCCCATGAACTTCGTACCCCACTTACAGTTATTGAGGG
GACCGTAGACGGAATACTGGACGGGGTATTTGAGGCTGATGCCCAGCACCTTACCACTATCAAAGAAGAATCCGCCACCC
TTACCCGCCTTATAAAGGACCTCCGGGATATATCTCTGGCTGAATCCGGCAAACTCAAGCTGGAAATGACCCAGCTGGAT
ATCGCAGACATTATCCGCCGTCAGGCCAAACAGGCATCTATACTGGCCAAAGACAAATCTATTGCCCTATTAAGTGATAT
TCCCGCTAATCTATCTACCGTTACGGGTGATGCCACCCGCTTAAACCAGATAACAGCCAACCTGCTCAGTAATGCCCTGC
GGCACACACCTGCCGGCGGGCAAATCAGCCTCAGCCTGAAAAATATGCTTTACCGGGATAAACCCGGGATTATGGTATCC
GTAACTGACAACGGAGAGGGGATACCACCGGCAGACTTACCCCATATTTTTGACCGCTTTTACCGGGTAAATACGTCCAG
AGCCCGAAGCGAAGGCGGCAGCGGGCTTGGTCTGGCTATTGTAAAAGAGATGGCAGAAGCCCACGGCGGTTATGTCTGGG
CCGAAAGCTTACTTGGGAAAGGCAGCACCTTTAACTACTGGCTGCCTGCCAGCCATACCTGA

Upstream 100 bases:

>100_bases
AAATCTGCGTAAAAAAATAGAGCCCGACCCCGAATCCCCAGCCTATATCCTGACCGTACACGGGGTAGGTTACAAGATGA
AAGACAAAGGGTAAAAGAGC

Downstream 100 bases:

>100_bases
TATCCCAACTTGAAAAAACCGCCTGATAATCTGAAAACTACCCCTTTCCCCCGGCAGCTATGTAAACTGCAAATACTGTT
AAATACAACCTGGTGTGCAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSRLSYKIFGALLLTVLLSVGLTSFAANQLTASQFRQYIIRGNTEFITSVESALGTYYAQYQGWDNVNGVLIQLLGSNGG
RLVLSDASGLIVADTQNKWIGYQTDEYSLSNGTLISISGTDAGYLYWIGSQGSGSGSGYGKGMQSGQNNSGNAAAGIISE
SQQQLLDEMNRSIWLSGGLAGLAALGLGLLLASQIIRPLKALSRSARRIAGGELSQRVKVDSRDELGELAESFNHMAQSL
ETNEQSRQRLLADIAHELRTPLTVIEGTVDGILDGVFEADAQHLTTIKEESATLTRLIKDLRDISLAESGKLKLEMTQLD
IADIIRRQAKQASILAKDKSIALLSDIPANLSTVTGDATRLNQITANLLSNALRHTPAGGQISLSLKNMLYRDKPGIMVS
VTDNGEGIPPADLPHIFDRFYRVNTSRARSEGGSGLGLAIVKEMAEAHGGYVWAESLLGKGSTFNYWLPASHT

Sequences:

>Translated_473_residues
MSRLSYKIFGALLLTVLLSVGLTSFAANQLTASQFRQYIIRGNTEFITSVESALGTYYAQYQGWDNVNGVLIQLLGSNGG
RLVLSDASGLIVADTQNKWIGYQTDEYSLSNGTLISISGTDAGYLYWIGSQGSGSGSGYGKGMQSGQNNSGNAAAGIISE
SQQQLLDEMNRSIWLSGGLAGLAALGLGLLLASQIIRPLKALSRSARRIAGGELSQRVKVDSRDELGELAESFNHMAQSL
ETNEQSRQRLLADIAHELRTPLTVIEGTVDGILDGVFEADAQHLTTIKEESATLTRLIKDLRDISLAESGKLKLEMTQLD
IADIIRRQAKQASILAKDKSIALLSDIPANLSTVTGDATRLNQITANLLSNALRHTPAGGQISLSLKNMLYRDKPGIMVS
VTDNGEGIPPADLPHIFDRFYRVNTSRARSEGGSGLGLAIVKEMAEAHGGYVWAESLLGKGSTFNYWLPASHT
>Mature_472_residues
SRLSYKIFGALLLTVLLSVGLTSFAANQLTASQFRQYIIRGNTEFITSVESALGTYYAQYQGWDNVNGVLIQLLGSNGGR
LVLSDASGLIVADTQNKWIGYQTDEYSLSNGTLISISGTDAGYLYWIGSQGSGSGSGYGKGMQSGQNNSGNAAAGIISES
QQQLLDEMNRSIWLSGGLAGLAALGLGLLLASQIIRPLKALSRSARRIAGGELSQRVKVDSRDELGELAESFNHMAQSLE
TNEQSRQRLLADIAHELRTPLTVIEGTVDGILDGVFEADAQHLTTIKEESATLTRLIKDLRDISLAESGKLKLEMTQLDI
ADIIRRQAKQASILAKDKSIALLSDIPANLSTVTGDATRLNQITANLLSNALRHTPAGGQISLSLKNMLYRDKPGIMVSV
TDNGEGIPPADLPHIFDRFYRVNTSRARSEGGSGLGLAIVKEMAEAHGGYVWAESLLGKGSTFNYWLPASHT

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=477, Percent_Identity=29.559748427673, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1786600, Length=264, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786783, Length=400, Percent_Identity=29, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=31.8996415770609, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=32.4427480916031, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789149, Length=346, Percent_Identity=29.4797687861272, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787894, Length=271, Percent_Identity=28.7822878228782, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790861, Length=389, Percent_Identity=27.5064267352185, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=31.7391304347826, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=31.0043668122271, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=33.4615384615385, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=31.4159292035398, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=32.034632034632, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=295, Percent_Identity=24.406779661017, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=28.5067873303167, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789808, Length=283, Percent_Identity=27.208480565371, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790551, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=428, Percent_Identity=24.0654205607477, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=287, Percent_Identity=25.0871080139373, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=265, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=281, Percent_Identity=24.9110320284698, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50752; Mature: 50621

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSYKIFGALLLTVLLSVGLTSFAANQLTASQFRQYIIRGNTEFITSVESALGTYYAQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YQGWDNVNGVLIQLLGSNGGRLVLSDASGLIVADTQNKWIGYQTDEYSLSNGTLISISGT
HCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCEECCCCCCEECCCCEEEEEECC
DAGYLYWIGSQGSGSGSGYGKGMQSGQNNSGNAAAGIISESQQQLLDEMNRSIWLSGGLA
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCHH
GLAALGLGLLLASQIIRPLKALSRSARRIAGGELSQRVKVDSRDELGELAESFNHMAQSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ETNEQSRQRLLADIAHELRTPLTVIEGTVDGILDGVFEADAQHLTTIKEESATLTRLIKD
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LRDISLAESGKLKLEMTQLDIADIIRRQAKQASILAKDKSIALLSDIPANLSTVTGDATR
HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHH
LNQITANLLSNALRHTPAGGQISLSLKNMLYRDKPGIMVSVTDNGEGIPPADLPHIFDRF
HHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHH
YRVNTSRARSEGGSGLGLAIVKEMAEAHGGYVWAESLLGKGSTFNYWLPASHT
HHCCCHHHHCCCCCCHHHHHHHHHHHHCCCEEEHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure 
SRLSYKIFGALLLTVLLSVGLTSFAANQLTASQFRQYIIRGNTEFITSVESALGTYYAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YQGWDNVNGVLIQLLGSNGGRLVLSDASGLIVADTQNKWIGYQTDEYSLSNGTLISISGT
HCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCEECCCCCCEECCCCEEEEEECC
DAGYLYWIGSQGSGSGSGYGKGMQSGQNNSGNAAAGIISESQQQLLDEMNRSIWLSGGLA
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCHH
GLAALGLGLLLASQIIRPLKALSRSARRIAGGELSQRVKVDSRDELGELAESFNHMAQSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ETNEQSRQRLLADIAHELRTPLTVIEGTVDGILDGVFEADAQHLTTIKEESATLTRLIKD
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LRDISLAESGKLKLEMTQLDIADIIRRQAKQASILAKDKSIALLSDIPANLSTVTGDATR
HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHH
LNQITANLLSNALRHTPAGGQISLSLKNMLYRDKPGIMVSVTDNGEGIPPADLPHIFDRF
HHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHH
YRVNTSRARSEGGSGLGLAIVKEMAEAHGGYVWAESLLGKGSTFNYWLPASHT
HHCCCHHHHCCCCCCHHHHHHHHHHHHCCCEEEHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]