Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 57234033

GI number: 57234033

Start: 1124972

End: 1125571

Strand: Direct

Name: yggV [C]

Synonym: DET1226

Alternate gene names: 57234033

Gene position: 1124972-1125571 (Clockwise)

Preceding gene: 57234041

Following gene: 57234032

Centisome position: 76.54

GC content: 52.5

Gene sequence:

>600_bases
ATGCCCAAGCTCCTGCTGGCAAGCAACAACCGGGGCAAGCTGAGAGAATATGCTTCTCTCCTTAGCGGTTCGGGTTTTGA
GCTTGTCACACCGGCAGATATGGGTATAGATATAACAGTTGCCGAAACCGGCACTACATTTGAAGAGAATGCCCGCTTGA
AAGCCGCCGCTCTGGCGGAAGCAAGCGGGATTCTTACTTTGGCAGATGACTCCGGTCTGGCAGTAGACGCTCTGGGGGGT
GAACCCGGGGTCTATTCCGCCCGCTATGCCGGGGAAAACGCTACGGATACAGACCGGAATGCATATCTTCTGTCTAAAAT
GCACACTATCCCCGCTGAAAAACGCACCGCCCGTTTCTGTTGTGTAATCGCCATTGCCCAGCCGGGCCATATCATCGCCA
CCTTTGAGGGTACTTGCGAAGGATTTATAAGCACTGAACCCCGCGGCACTAATGGATTTGGCTATGACCCCGTTTTTTAC
CTGCCGGAATACGGTAAAACTATGGCCGAACTCCCGTCTGAAATAAAAAACAGCATTTCCCACCGGTCTATAGCCGCCCA
AAAAGCCAGCCGGTTTCTGATCCAAATAGCCACTAGCTAG

Upstream 100 bases:

>100_bases
TGAGCCCCATCGCCTGCCGCTGGAGGAAATGGAATACACCACCATGCCTCAGGTATCCAAGAAACTGGCCGGACGCTTTA
AACCCCTGGAAGACTAGTTT

Downstream 100 bases:

>100_bases
TTAAGCTACACCAAATAAATTTACACACTCTGCTCTTTTTTTAATCCCGTTTTTATTCCTTGATAAACTATTTACTGCCT
CATTTTGAGCACAAAAATAT

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPKLLLASNNRGKLREYASLLSGSGFELVTPADMGIDITVAETGTTFEENARLKAAALAEASGILTLADDSGLAVDALGG
EPGVYSARYAGENATDTDRNAYLLSKMHTIPAEKRTARFCCVIAIAQPGHIIATFEGTCEGFISTEPRGTNGFGYDPVFY
LPEYGKTMAELPSEIKNSISHRSIAAQKASRFLIQIATS

Sequences:

>Translated_199_residues
MPKLLLASNNRGKLREYASLLSGSGFELVTPADMGIDITVAETGTTFEENARLKAAALAEASGILTLADDSGLAVDALGG
EPGVYSARYAGENATDTDRNAYLLSKMHTIPAEKRTARFCCVIAIAQPGHIIATFEGTCEGFISTEPRGTNGFGYDPVFY
LPEYGKTMAELPSEIKNSISHRSIAAQKASRFLIQIATS
>Mature_198_residues
PKLLLASNNRGKLREYASLLSGSGFELVTPADMGIDITVAETGTTFEENARLKAAALAEASGILTLADDSGLAVDALGGE
PGVYSARYAGENATDTDRNAYLLSKMHTIPAEKRTARFCCVIAIAQPGHIIATFEGTCEGFISTEPRGTNGFGYDPVFYL
PEYGKTMAELPSEIKNSISHRSIAAQKASRFLIQIATS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=189, Percent_Identity=49.7354497354497, Blast_Score=176, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21171; Mature: 21040

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLLLASNNRGKLREYASLLSGSGFELVTPADMGIDITVAETGTTFEENARLKAAALAE
CCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHHH
ASGILTLADDSGLAVDALGGEPGVYSARYAGENATDTDRNAYLLSKMHTIPAEKRTARFC
CCCEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCCEEEEHHHHCCCCCCCCCEEE
CVIAIAQPGHIIATFEGTCEGFISTEPRGTNGFGYDPVFYLPEYGKTMAELPSEIKNSIS
EEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
HRSIAAQKASRFLIQIATS
HHHHHHHHHCEEEEEEECC
>Mature Secondary Structure 
PKLLLASNNRGKLREYASLLSGSGFELVTPADMGIDITVAETGTTFEENARLKAAALAE
CCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHHH
ASGILTLADDSGLAVDALGGEPGVYSARYAGENATDTDRNAYLLSKMHTIPAEKRTARFC
CCCEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCCEEEEHHHHCCCCCCCCCEEE
CVIAIAQPGHIIATFEGTCEGFISTEPRGTNGFGYDPVFYLPEYGKTMAELPSEIKNSIS
EEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
HRSIAAQKASRFLIQIATS
HHHHHHHHHCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA